Eui Young So
YOU?
Author Swipe
View article: Myeloid Specific Ablation of SHIP1 Boosts ex vivo Expansion and Regulatory Function of Myeloid-Derived Suppressor Cells in Inflammatory Arthritis
Myeloid Specific Ablation of SHIP1 Boosts ex vivo Expansion and Regulatory Function of Myeloid-Derived Suppressor Cells in Inflammatory Arthritis Open
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous cell population and the immunosuppressive function of MDSCs has been well established in tumor microenvironment. Recent studies show that adoptive transfer of MDSCs can ameliorat…
View article: Enabling CAR-T Cell Immunotherapy in Glioblastoma by Modifying Tumor Microenvironment via Oncolytic Adenovirus Encoding Bispecific T Cell Engager
Enabling CAR-T Cell Immunotherapy in Glioblastoma by Modifying Tumor Microenvironment via Oncolytic Adenovirus Encoding Bispecific T Cell Engager Open
Recent clinical trials show that CAR-T cell therapies can initially blunt tumor growth in glioblastoma (GBM) patients. However, the tumor microenvironment activates mechanisms that inhibit tumor-killing potential of the CAR-T cells and lim…
View article: Magnesium supplementation improves diabetic mitochondrial and cardiac diastolic function
Magnesium supplementation improves diabetic mitochondrial and cardiac diastolic function Open
In heart failure and type 2 diabetes mellitus (DM), the majority of patients have hypomagnesemia, and magnesium (Mg) supplementation has improved cardiac function and insulin resistance. Recently, we have shown that DM can cause cardiac di…
View article: Loss of lipid phosphatase SHIP1 promotes macrophage differentiation through suppression of dendritic cell differentiation
Loss of lipid phosphatase SHIP1 promotes macrophage differentiation through suppression of dendritic cell differentiation Open
SH2-containing inositol 5'-phosphatase-1 (SHIP1) deficiency in mice results in abnormal myeloid expansion, and proinflammatory conditions in the lung. However, the mechanisms involved in SHIP1-mediated regulation of myeloid differentiation…
View article: The screening of a microRNA expression during development of human macrophages and mouse dendritic cells
The screening of a microRNA expression during development of human macrophages and mouse dendritic cells Open
There is increasing evidence showing specific roles of microRNA in cell differentiation and cancer progression. Here we examine miRNA profiles during maturation of monocytes and bone marrow-derived dendritic cells (BMDCs) in human and mous…
View article: Transgenic expression of non-structural genes of Theiler’s virus suppresses initial viral replication and pathogenesis of demyelination
Transgenic expression of non-structural genes of Theiler’s virus suppresses initial viral replication and pathogenesis of demyelination Open
View article: Fibersol-2 induces apoptosis of<i>Apc</i>-deficient colorectal Cancer (SW480) cells and decreases polyp formation in<i>Apc</i>MIN mice
Fibersol-2 induces apoptosis of<i>Apc</i>-deficient colorectal Cancer (SW480) cells and decreases polyp formation in<i>Apc</i>MIN mice Open
The consumption of dietary fibers has been implicated with a lowered risk of human colorectal cancer. Proposed mechanisms involve alterations in the stool consistency, transit time, and formation of short-chain fatty acid by dietary fiber …
View article: Tumor suppression by resistant maltodextrin, Fibersol-2
Tumor suppression by resistant maltodextrin, Fibersol-2 Open
Resistant maltodextrin Fibersol-2 is a soluble and fermentable dietary fiber that is Generally Recognized As Safe (GRAS) in the United States. We tested whether Fibersol-2 contains anti-tumor activity. Human colorectal cancer cell line, HC…