Eui‐Kyung Lee
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View article: Lifetime economic burden of hemophilia using a nationwide real-world healthcare data
Lifetime economic burden of hemophilia using a nationwide real-world healthcare data Open
Background Patients with hemophilia require lifelong treatment, but the real-world lifetime economic burden of hemophilia remains unclear. This study aims to estimate the lifetime economic burden of hemophilia using real-world data, accoun…
View article: Predictive model of public health impact of herpes zoster vaccination and related costs for adults aged ≥50 years in Republic of Korea
Predictive model of public health impact of herpes zoster vaccination and related costs for adults aged ≥50 years in Republic of Korea Open
Given the rapidly aging population in South Korea, the growing incidence and burden of herpes zoster (HZ) increase the need for HZ prevention. However, the public health impact of HZ vaccination has not been assessed in South Korea. This p…
View article: Comparison of Cost-Effectiveness Between Digital Health Interventions and Pharmacotherapy for Depression: Systematic Review
Comparison of Cost-Effectiveness Between Digital Health Interventions and Pharmacotherapy for Depression: Systematic Review Open
Background Owing to the unique characteristics of digital health interventions (DHIs), a tailored approach to economic evaluation is needed—one that is distinct from that used for pharmacotherapy. However, the absence of clear guidelines i…
View article: Comparative Effectiveness of Direct Oral Anticoagulants and Warfarin on Venous Thromboembolism in Cancer Patients
Comparative Effectiveness of Direct Oral Anticoagulants and Warfarin on Venous Thromboembolism in Cancer Patients Open
Introduction Venous thromboembolism (VTE) is a leading cause of mortality in cancer patients, and a substantial number of patients are being treated with oral anticoagulants. We aim to assess the comparative effectiveness of direct oral an…
View article: Assessing the impact of aggressive versus intermediate LDL-C goal achievement in Asian adults: a retrospective cohort study using national health insurance service-senior cohort
Assessing the impact of aggressive versus intermediate LDL-C goal achievement in Asian adults: a retrospective cohort study using national health insurance service-senior cohort Open
View article: Economic Burden of Cardiovascular Risk Factors in Patients with Ischemic Stroke Using Nationwide Claims Data in South Korea
Economic Burden of Cardiovascular Risk Factors in Patients with Ischemic Stroke Using Nationwide Claims Data in South Korea Open
View article: Factors associated with COVID-19 vaccination rates in countries with different income levels: a panel analysis
Factors associated with COVID-19 vaccination rates in countries with different income levels: a panel analysis Open
Vaccination rate and their associated factors differed across income levels. There is no universal strategy for boosting vaccination rates during a pandemic. Consequently, country specific approaches, including promotional programs to rais…
View article: Despite the pandemic: upward trajectories of medication adherence and persistence in patients with dyslipidemia
Despite the pandemic: upward trajectories of medication adherence and persistence in patients with dyslipidemia Open
Background Dyslipidemia, a major cardiovascular risk factor, requires consistent medication adherence, but new patients often struggle due to its asymptomatic nature. The COVID-19 pandemic has disrupted global healthcare. This study examin…
View article: Lipid-Based Nanoparticles Fused with Natural Killer Cell Plasma Membrane Proteins for Triple-Negative Breast Cancer Therapy
Lipid-Based Nanoparticles Fused with Natural Killer Cell Plasma Membrane Proteins for Triple-Negative Breast Cancer Therapy Open
Immunotherapy combined with chemicals and genetic engineering tools is emerging as a promising strategy to treat triple-negative breast cancer (TNBC), which is more aggressive with poorer progress than other breast cancer subtypes. In this…
View article: Factors Influencing Drug Shortages and Their Resolution in South Korean Community Pharmacies
Factors Influencing Drug Shortages and Their Resolution in South Korean Community Pharmacies Open
This study examines the influence of pharmacy purchasing power on drug shortages, identifying proximity to healthcare facilities and communication with prescribers as factors affecting the resolution rates. These findings provide valuable …
View article: Lipid-based nanoparticles mimicking natural killer cells for triple- negative breast cancer therapy
Lipid-based nanoparticles mimicking natural killer cells for triple- negative breast cancer therapy Open
Introduction: Immunotherapy combined with chemicals and genetic engineering tools is emerging as a promising strategy to treat triple-negative breast cancer (TNBC), which is more aggressive with poorer progress than other breast cancer sub…
View article: Lipid profile changes induced by glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: a systematic review and network meta-analysis
Lipid profile changes induced by glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: a systematic review and network meta-analysis Open
This study was conducted to investigate the effects of glucagon-like peptide-1 receptor (GLP-1) agonists on the lipid profiles of patients with type 2 diabetes. We retrieved the data of phase 3 randomized controlled trials on GLP-1 agonist…
View article: Evaluation of changes in the clinical benefits of oncology drugs over time following reimbursement using the ASCO-VF and the ESMO-MCBS
Evaluation of changes in the clinical benefits of oncology drugs over time following reimbursement using the ASCO-VF and the ESMO-MCBS Open
View article: Comparison of partitioned survival modeling with state transition modeling approaches with or without consideration of brain metastasis: a case study of Osimertinib versus pemetrexed-platinum
Comparison of partitioned survival modeling with state transition modeling approaches with or without consideration of brain metastasis: a case study of Osimertinib versus pemetrexed-platinum Open
View article: A nationwide analysis of the treatment patterns, survival, and medical costs in Korean patients with relapsed or refractory diffuse large B-cell lymphoma
A nationwide analysis of the treatment patterns, survival, and medical costs in Korean patients with relapsed or refractory diffuse large B-cell lymphoma Open
Background Approximately one-third of patients with diffuse large B-cell lymphoma (DLBCL) are refractory to treatment or experience relapse after initial therapy. Unfortunately, treatment options for older patients and those who experience…
View article: Cost-effectiveness of improving patients’ adherence to tuberculosis treatment in South Korea using discrete event simulation
Cost-effectiveness of improving patients’ adherence to tuberculosis treatment in South Korea using discrete event simulation Open
Improvements in adherence to TB treatment through the current TB program were cost-effective. The DES model accurately reflected the real world. Commitment programs to improve patient adherence may help manage TB nationwide.
View article: Lipid-Based Nanoparticles Mimicking Natural Killer Cells for Triple-Negative Breast Cancer Therapy
Lipid-Based Nanoparticles Mimicking Natural Killer Cells for Triple-Negative Breast Cancer Therapy Open
View article: Comparison of Perceived Importance and Performance of Community Pharmacists’ Role in South Korea During the Coronavirus Disease 2019 Pandemic
Comparison of Perceived Importance and Performance of Community Pharmacists’ Role in South Korea During the Coronavirus Disease 2019 Pandemic Open
Objective: This study aimed to identify the roles of community pharmacists (CPs) during the coronavirus disease 2019 (COVID-19) pandemic, the differences in their role performance compared with their perceived importance, and limiting fact…
View article: Comparison of factors affecting turnover intention by job field in biopharmaceutical industry in Korea: A questionnaire-based study
Comparison of factors affecting turnover intention by job field in biopharmaceutical industry in Korea: A questionnaire-based study Open
Background Excessive turnover in the biopharmaceutical industry can negatively impact public health and corporate management. This study aims to determine the difference in turnover intention by job field and compare the factors affecting …
View article: Factors influencing drug switching and changes in low-density lipoprotein-cholesterol levels with atorvastatin: a real-world observational study
Factors influencing drug switching and changes in low-density lipoprotein-cholesterol levels with atorvastatin: a real-world observational study Open
View article: Concomitant Use of Proton Pump Inhibitors and Palbociclib Among Patients With Breast Cancer
Concomitant Use of Proton Pump Inhibitors and Palbociclib Among Patients With Breast Cancer Open
Importance Proton pump inhibitors (PPIs) are commonly used drugs to relieve gastrointestinal tract symptoms, but their acid-inhibitory action negatively affects the bioavailability and clinical outcomes of orally administered concomitant d…
View article: Survival differences between patients with de novo and relapsed/progressed advanced non-small cell lung cancer without epidermal growth factor receptor mutations or anaplastic lymphoma kinase rearrangements
Survival differences between patients with de novo and relapsed/progressed advanced non-small cell lung cancer without epidermal growth factor receptor mutations or anaplastic lymphoma kinase rearrangements Open
View article: Estimating the Total Societal Cost of a Hexavalent Vaccine versus a Pentavalent Vaccine with Hepatitis B in South Korea
Estimating the Total Societal Cost of a Hexavalent Vaccine versus a Pentavalent Vaccine with Hepatitis B in South Korea Open
In South Korea, the ready-to-use hexavalent vaccine (against diphtheria, tetanus, pertussis, poliovirus, Haemophilus influenzae type b, and hepatitis B) is not listed despite its facility of no need to reconstitute. It, therefore, has the …
View article: Quantitative Benefit–Risk Assessment of COVID-19 Vaccines Using the Multi-Criteria Decision Analysis
Quantitative Benefit–Risk Assessment of COVID-19 Vaccines Using the Multi-Criteria Decision Analysis Open
In the early SARS-CoV-2 (COVID-19) pandemic, four major vaccines were approved despite limited efficacy and safety data through short regulatory review periods. Thus, it is necessary to assess the benefit-risk (BR) profiles of the COVID-19…
View article: Health-related quality of life in adult patients with asthma according to asthma control and severity: A systematic review and meta-analysis
Health-related quality of life in adult patients with asthma according to asthma control and severity: A systematic review and meta-analysis Open
Background: The utility values are increasingly being used in economic evaluations and health policy decision making. This study aims to conduct a systematic literature review and meta-analysis of the utility values for asthma, particularl…
View article: Visual Outcomes and Optical Quality of Accommodative, Multifocal, Extended Depth-of-Focus, and Monofocal Intraocular Lenses in Presbyopia-Correcting Cataract Surgery
Visual Outcomes and Optical Quality of Accommodative, Multifocal, Extended Depth-of-Focus, and Monofocal Intraocular Lenses in Presbyopia-Correcting Cataract Surgery Open
Importance A bayesian network meta-analysis (NMA) can help compare the various types of multifocal and monofocal intraocular lenses (IOLs) used in clinical practice. Objective To compare outcomes of presbyopia-correcting IOLs frequently re…
View article: Economic burden of brain metastases in non-small cell lung cancer patients in South Korea: A retrospective cohort study using nationwide claims data
Economic burden of brain metastases in non-small cell lung cancer patients in South Korea: A retrospective cohort study using nationwide claims data Open
Brain metastases (BM) are common in patients with non-small cell lung cancer (NSCLC). However, the pure economic burden of BM is unknown. This study aimed to evaluate the impact of BM on healthcare costs and resource utilization in patient…
View article: Understanding patient and physician responses to various cost-sharing programs for prescription drugs in South Korea: A multilevel analysis
Understanding patient and physician responses to various cost-sharing programs for prescription drugs in South Korea: A multilevel analysis Open
Introduction Patient and/or physician responses are a pivotal issue in designing rational cost-sharing programs under health insurance systems. Objectives This study aims to understand patient and/or physician responses to cost-sharing pro…
View article: Clinical manifestation, economic burden, and mortality in patients with transthyretin cardiac amyloidosis
Clinical manifestation, economic burden, and mortality in patients with transthyretin cardiac amyloidosis Open
Background Transthyretin cardiac amyloidosis, also known as transthyretin cardiomyopathy (ATTR-CM) is a poorly-recognized disease with delayed diagnosis and poor prognosis. This nationwide population-based study aimed to identify disease m…
View article: Optimal Indicator of Death for Using Real-World Cancer Patients' Data From the Healthcare System
Optimal Indicator of Death for Using Real-World Cancer Patients' Data From the Healthcare System Open
Background: Information on patient’s death is a major outcome of health-related research, but it is not always available in claim-based databases. Herein, we suggested the operational definition of death as an optimal indicator of real dea…