Eun‐Seok Shin
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View article: Diagnostic Performance of Angiography-Derived FFR According to the Analysis Factors
Diagnostic Performance of Angiography-Derived FFR According to the Analysis Factors Open
ClinicalTrials.gov Identifier: NCT06305572.
View article: Delineating coronary epicardial stenosis status from microvascular dysfunction using pressure-drop coefficient from multicenter ILIAS registry
Delineating coronary epicardial stenosis status from microvascular dysfunction using pressure-drop coefficient from multicenter ILIAS registry Open
View article: Drug‐Coated Balloon‐Based Versus Drug‐Eluting Stent‐Only Treatment for Large Vessel Coronary Artery Disease
Drug‐Coated Balloon‐Based Versus Drug‐Eluting Stent‐Only Treatment for Large Vessel Coronary Artery Disease Open
Background Drug‐coated balloon (DCB) treatment has shown outcomes comparable to drug‐eluting stent (DES) in small vessel coronary disease. However, evidence for its application in large vessel coronary artery disease (CAD) remains limited.…
View article: Identification of reactive CpGs and RNA expression in early COVID-19 through cis-eQTM analysis reflecting disease severity and recovery
Identification of reactive CpGs and RNA expression in early COVID-19 through cis-eQTM analysis reflecting disease severity and recovery Open
Multi-omics analyses of severe COVID-19 cases are crucial in deciphering the complex interplay between genetic and epigenetic factors. Here, we present an analysis of Expression Quantitative Trait Methylation (eQTM) to investigate the comp…
View article: Plaque vulnerability and thrombus formation according to area stenosis in chronic stable angina
Plaque vulnerability and thrombus formation according to area stenosis in chronic stable angina Open
View article: Drug-Coated Balloons-Based Intervention for Coronary Artery Disease
Drug-Coated Balloons-Based Intervention for Coronary Artery Disease Open
Drug-coated balloons (DCBs) provide a stent-free alternative, reducing risks like stent thrombosis and in-stent restenosis and the need for prolonged dual antiplatelet therapy. Recent studies show that DCBs can be effective and safe across…
View article: Definitions and standardized endpoints for the use of drug-coated balloon in coronary artery disease: consensus document of the Drug Coated Balloon Academic Research Consortium
Definitions and standardized endpoints for the use of drug-coated balloon in coronary artery disease: consensus document of the Drug Coated Balloon Academic Research Consortium Open
The Drug Coated Balloon Academic Research Consortium project originated from the lack of standardization and comparability between studies using drug-coated balloons in the treatment of obstructive coronary artery disease. This document is…
View article: Predictors of optimal angiographic lesion outcomes in drug-coated balloon treatment for de novo coronary artery disease
Predictors of optimal angiographic lesion outcomes in drug-coated balloon treatment for de novo coronary artery disease Open
Drug-coated balloon (DCB) treatment is an emerging strategy for de novo coronary artery disease (CAD), but procedural optimization remains uncertain. This study analyzed 317 patients who underwent DCB-based intervention for de novo CAD and…
View article: Healthome Polygon Framework: Comprehensive and Multi-dimensional Health Quantification Framework Using Artificial Intelligence and Multiomics Data
Healthome Polygon Framework: Comprehensive and Multi-dimensional Health Quantification Framework Using Artificial Intelligence and Multiomics Data Open
Background Quantifying human health and disease necessitates a transformative framework capable of integrating diverse biomedical data in a standardized manner. Such a system could enable precise preemptive health and disease prevention th…
View article: Identification of 17 novel epigenetic biomarkers associated with anxiety disorders using differential methylation analysis followed by machine learning-based validation
Identification of 17 novel epigenetic biomarkers associated with anxiety disorders using differential methylation analysis followed by machine learning-based validation Open
Our findings support the potential of blood liquid biopsy in enhancing the clinical utility of anxiety disorder diagnostics. This unique set of epigenetic biomarkers holds the potential for early diagnosis, prediction of treatment efficacy…
View article: Drug-Coated Balloon-Based Intervention for De Novo Acute Myocardial Infarction
Drug-Coated Balloon-Based Intervention for De Novo Acute Myocardial Infarction Open
In patients with de novo AMI, DCB-based PCI showed more favorable clinical outcomes after 2 years of follow-up compared to conventional DES-only PCI. DCB-based PCI may serve as a safe and effective alternative to DES-only PCI in carefully …
View article: Prognostic Value of Postpercutaneous Coronary Intervention Murray-Law-Based Quantitative Flow Ratio
Prognostic Value of Postpercutaneous Coronary Intervention Murray-Law-Based Quantitative Flow Ratio Open
In patients with intermediate lesions who underwent PCI with contemporary imaging or physiology guidance, lower post-PCI μQFR values predict subsequent adverse events. (Fractional FLow Reserve And IVUS for Clinical OUtcomes in Patients Wit…
View article: Comparison of Thick Biolimus A9-Eluting Stent and Thin Zotarolimus-Eluting Stent in Multi-Vessel Percutaneous Coronary Intervention
Comparison of Thick Biolimus A9-Eluting Stent and Thin Zotarolimus-Eluting Stent in Multi-Vessel Percutaneous Coronary Intervention Open
ClinicalTrials.gov Identifier: NCT01947439.
View article: Clinical impact of drug-coated balloon treatment of coronary artery disease in elderly patients
Clinical impact of drug-coated balloon treatment of coronary artery disease in elderly patients Open
The DCB-based PCI reduced stent burden, particularly in the usage of small diameter stents, and was associated with lower risks of MACE, target vessel revascularization, and major bleeding compared to DES-only PCI in elderly patients.
View article: Effectiveness of a Zotarolimus-Eluting Stent (Resolute Onyx<sup>TM</sup>) in Patients With Diffuse Long Coronary Artery Disease: Intravascular Ultrasound-guided vs. Angiography-guided Percutaneous Coronary Intervention
Effectiveness of a Zotarolimus-Eluting Stent (Resolute Onyx<sup>TM</sup>) in Patients With Diffuse Long Coronary Artery Disease: Intravascular Ultrasound-guided vs. Angiography-guided Percutaneous Coronary Intervention Open
View article: A Prospective Randomized Trial Comparing 2 Different Paclitaxel-Coated Balloons in De Novo Coronary Artery Disease
A Prospective Randomized Trial Comparing 2 Different Paclitaxel-Coated Balloons in De Novo Coronary Artery Disease Open
View article: Predictors of Optimal Angiographic Lesion Outcomes in Drug-Coated Balloon Treatment for De Novo Coronary Artery Disease: Insights from a Prospective Study and Intravascular Ultrasound Subgroup Analysis
Predictors of Optimal Angiographic Lesion Outcomes in Drug-Coated Balloon Treatment for De Novo Coronary Artery Disease: Insights from a Prospective Study and Intravascular Ultrasound Subgroup Analysis Open
Drug-coated balloon (DCB) treatment is an emerging strategy for de novo coronary artery disease (CAD), but procedural optimization remains uncertain. This study analyzed 317 patients who underwent DCB-based intervention for de novo CAD and…
View article: Safety and Efficacy of Pivot-Balloon for Severe Tricuspid Regurgitation: The First-in-Man Experiences
Safety and Efficacy of Pivot-Balloon for Severe Tricuspid Regurgitation: The First-in-Man Experiences Open
ClinicalTrials.gov Identifier: NCT05648838.
View article: Cost-effectiveness of Fractional Flow Reserve Versus Intravascular Ultrasound to Guide Percutaneous Coronary Intervention: Results From the FLAVOUR Study
Cost-effectiveness of Fractional Flow Reserve Versus Intravascular Ultrasound to Guide Percutaneous Coronary Intervention: Results From the FLAVOUR Study Open
ClinicalTrials.gov Identifier: NCT02673424.
View article: Long-term efficacy of drug-coated balloon-based treatment for de novo left anterior descending artery disease
Long-term efficacy of drug-coated balloon-based treatment for de novo left anterior descending artery disease Open
View article: Sex Difference in 5-year Relative Survival Following Percutaneous Coronary Intervention
Sex Difference in 5-year Relative Survival Following Percutaneous Coronary Intervention Open
Background: Survival rates following percutaneous coronary intervention (PCI) show variability across studies, particularly regarding sex-specific outcomes. Relative survival analysis, which considers survival patterns in sex- and age-matc…
View article: Clopidogrel Versus Aspirin as Chronic Maintenance Antiplatelet Monotherapy in Patients After Percutaneous Coronary Intervention With Chronic Kidney Disease: A Post Hoc Analysis of the HOST‐EXAM Trial
Clopidogrel Versus Aspirin as Chronic Maintenance Antiplatelet Monotherapy in Patients After Percutaneous Coronary Intervention With Chronic Kidney Disease: A Post Hoc Analysis of the HOST‐EXAM Trial Open
Background Clopidogrel monotherapy improved clinical outcomes compared with aspirin monotherapy during a chronic maintenance period in patients who underwent coronary stenting in the HOST‐EXAM (Harmonizing Optimal Strategy for Treatment of…
View article: Impact of proton pump inhibitor use on clinical outcomes in East Asian patients receiving clopidogrel following drug-eluting stent implantation
Impact of proton pump inhibitor use on clinical outcomes in East Asian patients receiving clopidogrel following drug-eluting stent implantation Open
Background Concomitant use of clopidogrel and proton pump inhibitor (PPI) is common, but PPI may reduce the antiplatelet effects of clopidogrel in patients undergoing percutaneous coronary intervention (PCI). We evaluated the impact of PPI…
View article: Discontinuation of β-blocker therapy in stabilised patients after acute myocardial infarction (SMART-DECISION): rationale and design of the randomised controlled trial
Discontinuation of β-blocker therapy in stabilised patients after acute myocardial infarction (SMART-DECISION): rationale and design of the randomised controlled trial Open
Introduction There is a lack of evidence to support the effectiveness of prolonged β-blocker therapy after stabilisation of patients with acute myocardial infarction (AMI) without heart failure (HF) or left ventricular systolic dysfunction…
View article: Angiographic Findings and Post–Percutaneous Coronary Intervention Fractional Flow Reserve
Angiographic Findings and Post–Percutaneous Coronary Intervention Fractional Flow Reserve Open
Importance The associations between angiographic findings and post–percutaneous coronary intervention (PCI) fractional flow reserve (FFR) and their clinical relevance according to residual functional disease burden have not been thoroughly…
View article: The East Asian Paradox: An Updated Position Statement on the Challenges to the Current Antithrombotic Strategy in Patients with Cardiovascular Disease
The East Asian Paradox: An Updated Position Statement on the Challenges to the Current Antithrombotic Strategy in Patients with Cardiovascular Disease Open
East Asian patients have reduced anti-ischemic benefits and increased bleeding risk during antithrombotic therapies compared with Caucasian patients. As potent P2Y 12 receptor inhibitors (e.g., ticagrelor and prasugrel) and direct oral ant…
View article: Impact of Drug-Coated Balloon-Based Revascularization in Patients with Chronic Total Occlusions
Impact of Drug-Coated Balloon-Based Revascularization in Patients with Chronic Total Occlusions Open
Background: Percutaneous coronary intervention (PCI) with a drug-eluting stent (DES) for chronic total coronary occlusions (CTOs) improves clinical symptoms and quality of life. However, data on drug-coated balloon (DCB)-based PCI in CTO l…
View article: Impact of hyperaemic stenosis resistance on long-term outcomes of stable angina in the ILIAS Registry
Impact of hyperaemic stenosis resistance on long-term outcomes of stable angina in the ILIAS Registry Open
The present study affirms the theoretical advantages of the HSR index for the detection of ischaemia-Âinducing coronary lesions in a large CCS population. (Inclusive Invasive Physiological Assessment in Angina Syndromes Registry [ILIAS Reg…
View article: Prognostic Impact of <i>CYP2C19</i> Genotypes on Long‐Term Clinical Outcomes in Older Patients After Percutaneous Coronary Intervention
Prognostic Impact of <i>CYP2C19</i> Genotypes on Long‐Term Clinical Outcomes in Older Patients After Percutaneous Coronary Intervention Open
Background Carriers of CYP2C19 loss‐of‐function alleles have increased adverse events after percutaneous coronary intervention, but limited data are available for older patients. We aimed to evaluate the prognostic impact of CYP2C19 genoty…
View article: Different association of atherogenic index of plasma with the risk of high platelet reactivity according to the presentation of acute myocardial infarction
Different association of atherogenic index of plasma with the risk of high platelet reactivity according to the presentation of acute myocardial infarction Open