Eva Decroli
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View article: Liothyronine Therapy in Hypothyroidism
Liothyronine Therapy in Hypothyroidism Open
Hypothyroidism is a clinical condition characterized by reduced production of thyroid hormones and is among the most common endocrine disorders, affecting about 3% of the general population, with a higher prevalence in women (5.1%) than in…
View article: The Role of Genomic Sequencing in Diabetes Mellitus
The Role of Genomic Sequencing in Diabetes Mellitus Open
Diabetes Mellitus is a chronic metabolic disorder caused by impaired insulin secretion and/or insulin resistance. Genetic testing through genomic sequencing is one of the modalities available for diabetes mellitus. Genomic sequencing is th…
View article: Marine-Lenhart Syndrome: Current Perspectives on Diagnosis and Management
Marine-Lenhart Syndrome: Current Perspectives on Diagnosis and Management Open
Marine-Lenhart syndrome (MLS) is an uncommon disorder characterised by the concurrent presence of Graves’ disease and hyperfunctioning thyroid nodules. Its global prevalence ranges between 2.7- 4.1% of Graves’ disease cases, presenting sig…
View article: CHARCOT ARTHROPATHY IN A CONTROLLED DIABETIC PATIENT
CHARCOT ARTHROPATHY IN A CONTROLLED DIABETIC PATIENT Open
INTRODUCTION/BACKGROUNDCharcot arthropathy is a severe complication of diabetes which is often diagnosed late, characterized by a red, warm, and swollen foot with bone abnormalities on imaging. Most studies report elevated HbA1c as a risk …
View article: AN UNUSUAL CASE PRESENTATION
AN UNUSUAL CASE PRESENTATION Open
INTRODUCTION/BACKGROUNDLung adenocarcinoma is a prevalent subtype of lung cancer known for its capacity to metastasize to various organs. In patients diagnosed with this cancer, thyroid nodules pose diagnostic challenges, as they may indic…
View article: PARATHYROID ADENOMA WITH PATHOLOGICAL FRACTURE IN YOUNG ADULT
PARATHYROID ADENOMA WITH PATHOLOGICAL FRACTURE IN YOUNG ADULT Open
INTRODUCTION/BACKGROUNDPrimary hyperparathyroidism is a condition of hypercalcemia caused by an increase in parathyroid hormone (PTH) levels. The most common cause of primary hyperparathyroidism is parathyroid adenoma (85%). Primary hyperp…
View article: PERMANENT CENTRAL DIABETES INSIPIDUS IN A POST TRANSSPHENOIDAL SURGERY PATIENT
PERMANENT CENTRAL DIABETES INSIPIDUS IN A POST TRANSSPHENOIDAL SURGERY PATIENT Open
INTRODUCTION/BACKGROUNDDiabetes insipidus (DI) is a disorder characterized by the excretion of large volumes of hypotonic urine. Four types of DI must be differentiated: central DI (cDI), nephrogenic DI (nDI), gestational DI, and primary p…
View article: PITUITARY HYPOPLASIA PRESENTING WITH HYPOPITUITARISM
PITUITARY HYPOPLASIA PRESENTING WITH HYPOPITUITARISM Open
INTRODUCTION/BACKGROUNDHypopituitarism is a deficiency of one or more hormones secreted by the anterior or posterior pituitary gland. It is a rare condition, with a prevalence of 46 cases per 100,000 population. It can be caused by several…
View article: MACROPROLACTINOMA IN A POST-MENOPAUSAL WOMAN
MACROPROLACTINOMA IN A POST-MENOPAUSAL WOMAN Open
INTRODUCTION/BACKGROUNDProlactinoma is a type of benign pituitary tumor that secretes prolactin derived from lactotropes and constitutes 50% of all pituitary adenomas. Microprolactinoma (diameter <10 mm) is the more common type and rarely …
View article: Difference Analysis of N-Terminal B-Type Natriuretic Peptide, High-Sensitivity Troponin I, and Endothelin-1 Levels in Patients With Normotensive and Hypertensive Acute Heart Failure
Difference Analysis of N-Terminal B-Type Natriuretic Peptide, High-Sensitivity Troponin I, and Endothelin-1 Levels in Patients With Normotensive and Hypertensive Acute Heart Failure Open
In patients with normotensive AHF, higher levels of hs-troponin I were observed, with no significant differences in other cardiac biomarkers. A higher proportion of males and a lower prevalence of hypertension as a risk factor were also no…
View article: In-hospital mortality and its determinant factors among patients with sepsis
In-hospital mortality and its determinant factors among patients with sepsis Open
BACKGROUNDSepsis is a heterogeneous syndrome characterized by a variety of clinical features. Multiple studies have identified sepsis as the leading cause of death in hospitalized patients. A comprehensive report on the incidence, clinical…
View article: Lifestyle of type 2 diabetes mellitus patients with peripheral neuropathy: Phenomenological study
Lifestyle of type 2 diabetes mellitus patients with peripheral neuropathy: Phenomenological study Open
Objective: To explore the lifestyle-related characteristics of people having type 2 diabetes mellitus with peripheral neuropathy.Method: The phenomenological study was conducted from July 5 to September 18, 2021, at Sadabuan Health Centre,…
View article: Body mass index and total testosterone level in obese male pre-diabetic patients: correlation with homeostasis model assessment of insulin resistance
Body mass index and total testosterone level in obese male pre-diabetic patients: correlation with homeostasis model assessment of insulin resistance Open
Link of Video Abstract: https://www.youtube.com/watch?v=zABLxwmAXtA Introduction: Men with comorbidities are typically more likely to have testosterone insufficiency. In this study, total testosterone levels in obese male pre-diabetic pati…
View article: Dietary Regulation As A Factor Predicting Quality of Life in Diabetic Peripheral Neuropathy Patients
Dietary Regulation As A Factor Predicting Quality of Life in Diabetic Peripheral Neuropathy Patients Open
Diabetic peripheral neuropathy is a complication of diabetes mellitus with the number of sufferers continuing to increase from time to time. A decrease in quality of life occurs as this disease progresses, both in physical, mental, and soc…
View article: Spiritual Experience of Type 2 Diabetes Mellitus Patients: Phenomenological Study
Spiritual Experience of Type 2 Diabetes Mellitus Patients: Phenomenological Study Open
Diabetes mellitus is a chronic disease that every sufferer must undergo this condition for life. Spirituality is an aspect that cannot be separated from diabetics in living their lives. This study aims to explore the spiritual aspects of d…
View article: Comorbidities of Gestational Diabetes Mellitus and Urinary Tract Infection: A Case Report
Comorbidities of Gestational Diabetes Mellitus and Urinary Tract Infection: A Case Report Open
Background: Gestational diabetes mellitus (GDM) is defined as a condition of glucose intolerance that is found during pregnancy. In pregnant women, urinary tract infection (UTI) is one of the most common bacterial infections that can be fo…
View article: Correlation between Insulin Resistance with Soluble CD40 Ligand and Plasminogen Activator Inhibitor-1 Plasma in Pre-diabetic Patients
Correlation between Insulin Resistance with Soluble CD40 Ligand and Plasminogen Activator Inhibitor-1 Plasma in Pre-diabetic Patients Open
BACKGROUND: The main condition of pre-diabetes is insulin resistance that can lead to a prothrombotic state. AIM: This study aims to correlate insulin resistance with soluble CD40 ligand (sCD40L) and plasminogen activator inhibitor-1 (PAI-…
View article: The Risk Factors of Coronary Heart Disease and its Relationship with Endothelial Nitric Oxide Synthase
The Risk Factors of Coronary Heart Disease and its Relationship with Endothelial Nitric Oxide Synthase Open
BACKGROUND: Coronary heart disease (CHD) is the leading cause of death and start with injury to the endothelium of a coronary artery. The common feature of endothelial dysfunction is a decrease of nitric oxide (NO) bioavailability that reg…
View article: Expression of CCL27 in Middle Ear Cholesteatoma
Expression of CCL27 in Middle Ear Cholesteatoma Open
BACKGROUND: Cholesteatoma is a lesion of the temporal bone lined by stratified squamous epithelium that contains desquamated keratin. Cholesteatoma is considered more aggressive during childhood. The molecular mechanism of the pathogenesis…
View article: COVID-19 dengan Komorbid Tuberkulosis Paru dan Diabetes Melitus
COVID-19 dengan Komorbid Tuberkulosis Paru dan Diabetes Melitus Open
A 61-year-old man was admitted a confirmed COVID-19 with comorbid pulmonary tuberculosis and type 2 diabetes mellitus. The patient was given favipiravir therapy, category 1 of antituberculosis drug, and insulin therapy. The patient respond…
View article: Characteristics of Non-Alcoholic Fatty Liver Disease Patients at Dr. M. Djamil General Hospital Padang
Characteristics of Non-Alcoholic Fatty Liver Disease Patients at Dr. M. Djamil General Hospital Padang Open
Background: Non-Alcoholic Fatty Liver Disease (NAFLD) is emerging as chronic liver disease, both in developed and developing countries. NAFLD affects up to 25% population worldwide. The incidence of NAFLD associated with various risk facto…
View article: THE ROLE OF INTERLEUKIN-4 GENE PROMOTER POLYMORPHISMS IN GRAVES’ DISEASE
THE ROLE OF INTERLEUKIN-4 GENE PROMOTER POLYMORPHISMS IN GRAVES’ DISEASE Open
Objective: This study was conducted to prove the role of interleukin-4 gene promoter polymorphisms in Graves’ disease patients in M Djamil General Hospital Padang, Indonesia.
Methods: This study was conducted from August 2015 until Decemb…
View article: Correlation between Interleukin-4 Gene Promoter Polymorphisms with Thyrotropin Receptor Antibody and Transforming Growth Factor-β
Correlation between Interleukin-4 Gene Promoter Polymorphisms with Thyrotropin Receptor Antibody and Transforming Growth Factor-β Open
AIM: The aim of this study was to determine the correlation between interleukin-4 (IL-4) gene promoter polymorphisms with thyrotropin receptor antibody (TRAb) and transforming growth factor-β (TGF-β). METHODS: This study was conducted from…
View article: Vitamin D Receptor Gene Polymorphism FokI and 25-Hydroxy Vitamin D Levels among Indonesian Diabetic Foot Patients
Vitamin D Receptor Gene Polymorphism FokI and 25-Hydroxy Vitamin D Levels among Indonesian Diabetic Foot Patients Open
BACKGROUND: Vitamin D and VDRs FokI has been reported to be strongly associated with type 2 diabetes mellitus (T2DM) through controlling inflammation of endothelial cells in diabetic foot cases. AIM: This study aimed to detect Vitamin D re…
View article: The Relationship between Endothelial Nitric Oxide Synthase with Dyslipidemia in Coronary Heart Disease
The Relationship between Endothelial Nitric Oxide Synthase with Dyslipidemia in Coronary Heart Disease Open
BACKGROUND: Dyslipidemia is a medical condition that refers to an abnormal of blood lipids level, most common is hyperlipidemia. Elevation of blood lipid such as cholesterol, triglycerides, low-density lipoprotein (LDL) cholesterol, or a l…
View article: THE PROFILE OF THYROTROPIN-RELEASING HORMONE, T-REGULATOR, AND INTERLEUKIN-4 OF UNTREATED GRAVES’ DISEASE IN INDONESIA
THE PROFILE OF THYROTROPIN-RELEASING HORMONE, T-REGULATOR, AND INTERLEUKIN-4 OF UNTREATED GRAVES’ DISEASE IN INDONESIA Open
Objective: This study was conducted to the profile of hormonal and immunological aspects, which is thyrotropin-releasing hormone (TRH), T-regulator (T-reg) Forkhead box P3 (FOXP3) gene polymorphism, and interleukin-4 (IL-4) of untreated Gr…
View article: Sepsis in Latent Autoimmune Diabetes in Adults with Diabetic Ketoacidosis: A Case Report
Sepsis in Latent Autoimmune Diabetes in Adults with Diabetic Ketoacidosis: A Case Report Open
BACKGROUND: This case report intends to highlight the challenge in diagnosing type 1 diabetes on an adult patient. Latent Autoimmune Diabetes in Adult (LADA) types I diabetes Mellitus, which found in adulthood and characterised by progress…
View article: Relationship of Interleukin-6 Trans-Signaling and Coronary Heart Disease in Young Adults: a Case-Control Study in Indonesia
Relationship of Interleukin-6 Trans-Signaling and Coronary Heart Disease in Young Adults: a Case-Control Study in Indonesia Open
Interleukin-6 (IL-6) has been reported to be related to coronary heart disease (CHD). It is proposed that the IL-6 trans-signaling pathway is responsible for the inflammatory effect in diseases, including CHD. In Asian countries, CHD tends…
View article: The Effect of Thionamide to TRH, TSH, IL-4, T-REG, and Anti-TPO in Graves’ Disease
The Effect of Thionamide to TRH, TSH, IL-4, T-REG, and Anti-TPO in Graves’ Disease Open
The most common cause of hyperthyroidism is Graves' disease. TRH and TSH are hormonal factors that modulate and control thyroid function in Graves' disease. In the immunological aspect, Graves' disease is played by the role of T-reg, IL-4,…
View article: The Percentage of Depressive Symptoms in Patients with Type 2 Diabetes Mellitus in M Djamil General Hospital Padang, Indonesia
The Percentage of Depressive Symptoms in Patients with Type 2 Diabetes Mellitus in M Djamil General Hospital Padang, Indonesia Open
The objectives of this study are to find the percentage of depressive symptoms and the most appeared clinical manifestation of depressive symptoms.A total of 2016 patient with type 2 diabetes from M Djamil General Hospital had fulfilled th…