Enrique Gómez‐Barrena
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Guided Personalized Surgery (GPS) in Posterostabilized Total Knee Replacement: A Radiological Study Open
Background: Surgical accuracy in total knee replacement (TKR) may vary with the surgeon, the patient preoperative deformity, and the guiding system to perform the procedure. Navigation systems attempt to increase the intraoperative informa…
In vivo reduction of biofilm seeded on orthopaedic implants Open
Aims Electromagnetic induction heating has demonstrated in vitro antibacterial efficacy over biofilms on metallic biomaterials, although no in vivo studies have been published. Assessment of side effects, including thermal necrosis of adja…
View article: New materials and complications of prostheses in humans: situation in Spain
New materials and complications of prostheses in humans: situation in Spain Open
Prostheses or implantable medical devices (IMDs) are parts made of natural or artificial materials intended to replace a body structure and therefore must be well tolerated by living tissues. The types of IMDs currently available and usabl…
Long bone uninfected non-union: grafting techniques Open
Long bone non-unions represent a serious clinical and socioeconomical problem due to the prolonged episodes, frequent sequelae, and variable treatment effectiveness. Bone grafts, classically involving the autologous iliac crest graft as th…
Association between Bone Turnover Markers and Fracture Healing in Long Bone Non-Union: A Systematic Review Open
Background: Fracture healing is a very complex and well-orchestrated regenerative process involving many cell types and molecular pathways. Despite the high efficiency of this process, unsatisfying healing outcomes, such as non-union, occu…
Biofilm on total joint replacement materials can be reduced through electromagnetic induction heating using a portable device Open
Background: Periprosthetic joint infection is a serious complication following joint replacement. The development of bacterial biofilms bestows antibiotic resistance and restricts treatment via implant retention surgery. Electromagnetic in…
Volume and location of bone regeneration after autologous expanded mesenchymal stromal cells in hip osteonecrosis Open
Aims Successful cell therapy in hip osteonecrosis (ON) may help to avoid ON progression or total hip arthroplasty (THA), but the achieved bone regeneration is unclear. The aim of this study was to evaluate amount and location of bone regen…
Complications and surgical treatment after pathological fracture associated to HIV secondary disease. A case report Open
Due to advances in retroviral treatment, human immunodeficiency virus (HIV)-related disease may become chronic and the patient survival has substantially increased. Osteoarticular disease in those patients include multifocal osteonecrosis …
Extensor mechanism ruptures Open
Native patellar tendon injuries are seen in younger patients compared to quadriceps tendon ruptures. Up to a third of the patients may have local (antecedent tendinopathy and cortisone injections) or systemic risk factors (obesity, diabete…
Explant analysis and implant registries are both needed to further improve patient safety Open
In the early days of total joint replacement, implant fracture, material problems and wear presented major problems for the long-term success of the operation. Today, failures directly related to the implant comprise only 2–3% of the reaso…
View article: Prevention of Periprosthetic Joint Infection in Total Hip and Knee Replacement: One European Consensus
Prevention of Periprosthetic Joint Infection in Total Hip and Knee Replacement: One European Consensus Open
Periprosthetic joint infection (PJI) is a devastating complication in total hip and knee replacement. Its prevention is key to decrease the incidence and avoid some consequences that seriously impact patients and health systems. In view of…
One-Year, Efficacy and Safety Open Label Study, with a Single Injection of a New Hyaluronan for Knee OA: The SOYA Trial Open
With just a single intra-articular injection, this not controlled trial suggests that MPS-HA2% is effective 12 months after the procedure in most cases. Patient tolerability and safety were both optimal (NCT03852914).
View article: The contribution of the histopathological examination to the diagnosis of adverse local tissue reactions in arthroplasty
The contribution of the histopathological examination to the diagnosis of adverse local tissue reactions in arthroplasty Open
The histopathological examination of the periprosthetic soft tissue and bone has contributed to the identification and description of the morphological features of adverse local tissue reactions (ALTR)/adverse reactions to metallic debris …
Both younger and elderly patients in pain are willing to undergo knee replacement despite the COVID‐19 pandemic: a study on surgical waiting lists Open
Purpose To identify factors influencing patient’s availability to re‐schedule primary total knee replacement (TKR) or revision (RKR) surgery after the lockdown (March–May 2020) during the COVID‐19 pandemic. Methods A prospective cohort stu…
Epidemiology of long bone non-unions in Spain Open
Epidemiological and ecological studies on long bone non-unions (NU) are scarce, based on different populations and methodologies. The aim of this study was to produce a descriptive analysis of the femur, tibia, and humerus non-union epidem…
Implantation of autologous Expanded Mesenchymal Stromal Cells in Hip Osteonecrosis through Percutaneous Forage: Evaluation of the Operative Technique Open
Bone forage to treat early osteonecrosis of the femoral head (ONFH) has evolved as the channel to percutaneously deliver cell therapy into the femoral head. However, its efficacy is variable and the drivers towards higher efficacy are curr…
View article: Osteonecrosis of the Femoral Head Safely Healed with Autologous, Expanded, Bone Marrow-Derived Mesenchymal Stromal Cells in a Multicentric Trial with Minimum 5 Years Follow-Up
Osteonecrosis of the Femoral Head Safely Healed with Autologous, Expanded, Bone Marrow-Derived Mesenchymal Stromal Cells in a Multicentric Trial with Minimum 5 Years Follow-Up Open
Background: Osteonecrosis (ON) of the femoral head represents a potentially severe disease of the hip where the lack of bone regeneration may lead to femoral head collapse and secondary osteoarthritis, with serious pain and disability. The…
An update about molecular biology techniques to detect orthopaedic implant-related infections Open
Despite different criteria to diagnose a prosthetic joint infection (PJI), aetiological diagnosis of the causing microorganism remains essential to guide treatment. Molecular-biology-based PJI diagnosis is progressing (faster, higher speci…
Frontiers in non-union research Open
Multifactorial aetiology defines non-unions, with a biological and a mechanical distortion of the timeline of bone healing. Research on new advances to increase osteogenesis and promote non-union healing is strongly directed towards new fo…
Resuming elective hip and knee arthroplasty after the first phase of the SARS-CoV-2 pandemic: the European Hip Society and European Knee Associates recommendations Open
Purpose The Covid-19 pandemic has disrupted health care systems all over the world. Elective surgical procedures have been postponed and/or cancelled. Consensus is, therefore, required related to the factors that need to be in place before…
Recommendations for resuming elective hip and knee arthroplasty in the setting of the SARS-CoV-2 pandemic: the European Hip Society and European Knee Associates Survey of Members Open
Purpose The COVID-19 pandemic has disrupted the health care system around the entire globe. A consensus is needed about resuming total hip and knee procedures. The European Hip Society (EHS) and the European Knee Association (EKA) formed a…
Resuming hip and knee arthroplasty after COVID-19: ethical implications for wellbeing, safety and the economy Open
Reinstating elective hip and knee arthroplasty services presents significant challenges. We need to be honest about the scale of the obstacles ahead and realise that the health challenges and economic consequences of the COVID-19 pandemic …
Defining the Most Effective Patient Blood Management Combined with Tranexamic Acid Regime in Primary Uncemented Total Hip Replacement Surgery Open
The application of patient blood management (PBM) combined with tranexamic acid administration (TXA) results in decreased total blood loss volume (TVB) and transfusions in total hip replacements (THRs). Dosages, timing, and routes of admin…
Limiting spread of COVID-19 in an orthopaedic department—a perspective from Spain Open
Besides national and international recommendations, orthopaedic departments face significant changes in daily activity and serious issues to maintain their standards in musculoskeletal care during the pandemic Covid-19 crisis that we are f…
Complications in Total Joint Arthroplasties Open
Total joint arthroplasties (TJA) are today considered highly successful operations [...]
CORR Insights®: High Oxidation Stability of Tea Polyphenol-stabilized Highly Crosslinked UHMWPE Under an in Vitro Aggressive Oxidative Condition Open
Where Are We Now? The risks associated with polyethylene oxidation, including wear and osteolysis, prompted the use of polyethylene crosslinking as a way to improve wear performance. This was followed by thermal treatments, which decreased…