Eva Grekowitz
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View article: Development and Validation of a Disease Severity Index for Patients With Cold Urticaria
Development and Validation of a Disease Severity Index for Patients With Cold Urticaria Open
The SICU is the first validated disease-specific patient-reported outcome measure (PROM) for assessing ColdU disease severity. This PROM will facilitate patient care by evaluating disease severity and consequently better informing physicia…
View article: Validation of the Urticaria Activity Score for Cold Urticaria
Validation of the Urticaria Activity Score for Cold Urticaria Open
The ColdUAS is a newly developed PROM to assess disease activity in adolescent and adult patients with typical or atypical ColdU, tailored to the specific symptoms of these patients. The validation study confirmed its validity and reliabil…
View article: The Mastocytosis Control Test: A Patient-Reported Outcome Measure Assessing Disease Control
The Mastocytosis Control Test: A Patient-Reported Outcome Measure Assessing Disease Control Open
The MCT is a disease-specific, valid, and reliable PROM for adult patients with nonadvanced disease. It may measure and monitor disease control in routine daily practice and clinical trials.
View article: Validation of the Cholinergic Urticaria Activity Score (CholUAS)
Validation of the Cholinergic Urticaria Activity Score (CholUAS) Open
The validated CholUAS is ready for use in clinical trials and routine clinical practice.
View article: An algorithm for the diagnosis and treatment of chronic inducible urticaria, 2024 update
An algorithm for the diagnosis and treatment of chronic inducible urticaria, 2024 update Open
Chronic inducible urticaria (CIndU) is defined by pruritic wheal formation and/or angioedema in response to a definite and specific trigger.1, 2 CIndUs account for 20–30% of all cases of chronic urticaria, that is, urticaria that lasts lon…
View article: Disease modification in chronic spontaneous urticaria
Disease modification in chronic spontaneous urticaria Open
Chronic spontaneous urticaria (CSU) is a debilitating, inflammatory skin condition characterized by infiltrating immune cells. Available treatments are limited to improving the signs and symptoms. There is an unmet need to develop therapie…
View article: Anti‐KIT antibody, barzolvolimab, reduces skin mast cells and disease activity in chronic inducible urticaria
Anti‐KIT antibody, barzolvolimab, reduces skin mast cells and disease activity in chronic inducible urticaria Open
Background Chronic inducible urticaria (CIndU) is characterized by mast cell (MC)‐mediated wheals in response to triggers: cold in cold urticaria (ColdU) and friction in symptomatic dermographism (SD). KIT receptor activation by stem cell …
View article: Evidence for histamine release in chronic inducible urticaria – A systematic review
Evidence for histamine release in chronic inducible urticaria – A systematic review Open
Background Chronic inducible urticaria (CIndU) constitutes a group of nine different CIndUs in which pruritic wheals and/or angioedema occur after exposure to specific and definite triggers. Histamine released from activated and degranulat…
View article: Disease Impact, Diagnostic Delay, and Unmet Medical Needs of Patients With Cholinergic Urticaria in German-Speaking Countries
Disease Impact, Diagnostic Delay, and Unmet Medical Needs of Patients With Cholinergic Urticaria in German-Speaking Countries Open
Background Cholinergic urticaria (CholU) is a common type of chronic inducible urticaria. Little is known about the burden of the disease and its unmet medical needs. Aim To characterize the unmet medical needs of patients with CholU. Meth…