Eva Grüner
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View article: Mpox-Specific Immune Responses Elicited by Vaccination or Infection in People With HIV
Mpox-Specific Immune Responses Elicited by Vaccination or Infection in People With HIV Open
In the recent mpox outbreak, people with human immunodeficiency virus (PWH) were at high risk both for contracting infection and for a more severe disease course. We studied cellular and humoral immune responses elicited by mpox infection …
View article: Persistent immune abnormalities discriminate post-COVID syndrome from convalescence
Persistent immune abnormalities discriminate post-COVID syndrome from convalescence Open
Background Innate lymphoid cells (ILCs) are key organizers of tissue immune responses and regulate tissue development, repair, and pathology. Persistent clinical sequelae beyond 12 weeks following acute COVID-19 disease, named post-COVID s…
View article: Modification of the penicillin-binding-protein 3 as a source of resistance to broad-spectrum cephalosporins in <i>Escherichia coli</i>
Modification of the penicillin-binding-protein 3 as a source of resistance to broad-spectrum cephalosporins in <i>Escherichia coli</i> Open
Multidrug-resistant Gram-negative bacteria are one of the major threats to human health, largely due to the dissemination of some high-risk successful multidrug-resistant clones. 1 Of particular concern is the resistance to ß-lactams, beca…
View article: Persistent immune abnormalities discriminate post-COVID syndrome from convalescence
Persistent immune abnormalities discriminate post-COVID syndrome from convalescence Open
Innate lymphoid cells (ILCs) are key organizers of tissue immune responses and regulate tissue development, repair, and pathology. Persistent clinical sequelae beyond 12 weeks following acute COVID-19 disease, named post-COVID syndrome (PC…
View article: Characterization of SARS-CoV-2 Escape Mutants to a Pair of Neutralizing Antibodies Targeting the RBD and the NTD
Characterization of SARS-CoV-2 Escape Mutants to a Pair of Neutralizing Antibodies Targeting the RBD and the NTD Open
Mutations in the spike protein of SARS-CoV-2 can lead to evasion from neutralizing antibodies and affect the efficacy of passive and active immunization strategies. Immunization of mice harboring an entire set of human immunoglobulin varia…
View article: A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS‐CoV‐2 infection model
A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS‐CoV‐2 infection model Open
TRIANNI mice carry an entire set of human immunoglobulin V region gene segments and are a powerful tool to rapidly isolate human monoclonal antibodies. After immunizing these mice with DNA encoding the spike protein of SARS‐CoV‐2 and boost…
View article: A pair of non-competing neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model
A pair of non-competing neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model Open
TRIANNI mice carry an entire set of human immunoglobulin V region gene segments and are a powerful tool to rapidly generate human monoclonal antibodies. After immunizing these mice against the spike protein of SARS-CoV-2, we identified 29 …