Eva Maxfield Brown
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View article: Collecting Qualitative Data at Scale with Large Language Models: A Case Study
Collecting Qualitative Data at Scale with Large Language Models: A Case Study Open
Chatbots have shown promise as tools to scale qualitative data collection. Recent advances in Large Language Models (LLMs) could accelerate this process by allowing researchers to easily deploy sophisticated interviewing chatbots. We test …
View article: Measuring Software Innovation with Open Source Software Development Data
Measuring Software Innovation with Open Source Software Development Data Open
Existing innovation metrics inadequately capture software innovation, creating blind spots for researchers and policymakers seeking to understand and foster technological innovation in an increasingly software-defined economy. This paper i…
View article: Laboratory-Scale AI: Open-Weight Models are Competitive with ChatGPT Even in Low-Resource Settings
Laboratory-Scale AI: Open-Weight Models are Competitive with ChatGPT Even in Low-Resource Settings Open
The rapid proliferation of generative AI has raised questions about the\ncompetitiveness of lower-parameter, locally tunable, open-weight models\nrelative to high-parameter, API-guarded, closed-weight models in terms of\nperformance, domai…
View article: The Impact of iBuying is About More Than Just Racial Disparities: Evidence from Mecklenburg County, NC
The Impact of iBuying is About More Than Just Racial Disparities: Evidence from Mecklenburg County, NC Open
Instant buyers (iBuyers)—companies that buy and sell homes based on automated valuation models (AVMs)—now hold more than 5% market share in some USA cities. In this work, we investigate the fairness of iBuyers by constructing a dataset tha…
View article: Biomedical Open Source Software: Crucial Packages and Hidden Heroes
Biomedical Open Source Software: Crucial Packages and Hidden Heroes Open
Despite the importance of scientific software for research, it is often not formally recognized and rewarded. This is especially true for foundational libraries, which are hidden below packages visible to the users (and thus doubly hidden,…
View article: Mapping variation in the morphological landscape of human cells with optical pooled CRISPRi screening
Mapping variation in the morphological landscape of human cells with optical pooled CRISPRi screening Open
The contributions of individual genes to cell-scale morphology and cytoskeletal organization are challenging to define due to the wide intercellular variation of these complex phenotypes. We leveraged the controlled nature of image-based p…
View article: Mapping variation in the morphological landscape of human cells with optical pooled CRISPRi screening
Mapping variation in the morphological landscape of human cells with optical pooled CRISPRi screening Open
The contributions of individual genes to cell-scale morphology and cytoskeletal organization are challenging to define due to the wide intercellular variation of these complex phenotypes. We leveraged the controlled nature of image-based p…
View article: A Dependency Graph for 460,000 Papers and Their Software Mentions from the CZI Software Mentions Dataset
A Dependency Graph for 460,000 Papers and Their Software Mentions from the CZI Software Mentions Dataset Open
Using the CZI Software Mentions Dataset and ecosyste.ms we create a graph of papers, their mentioned software, and recursive dependencies of each piece of software across 466,000 papers and three software registries (PyPI, CRAN, and BioCon…
View article: A Dependency Graph for 460,000 Papers and Their Software Mentions from the CZI Software Mentions Dataset
A Dependency Graph for 460,000 Papers and Their Software Mentions from the CZI Software Mentions Dataset Open
Using the CZI Software Mentions Dataset and ecosyste.ms we create a graph of papers, their mentioned software, and recursive dependencies of each piece of software across 466,000 papers and three software registries (PyPI, CRAN, and BioCon…
View article: Collecting Qualitative Data at Scale with Large Language Models: A Case Study
Collecting Qualitative Data at Scale with Large Language Models: A Case Study Open
Chatbots have shown promise as tools to scale qualitative data collection. Recent advances in Large Language Models (LLMs) could accelerate this process by allowing researchers to easily deploy sophisticated interviewing chatbots. We test …
View article: Deactivation with and without Representation: The Role of Dispute Arbitration for Seattle Rideshare Drivers
Deactivation with and without Representation: The Role of Dispute Arbitration for Seattle Rideshare Drivers Open
For drivers who depend on an app in order to make a living, losing access to their account (or, being deactivated) is the equivalent of being digitally fired. Transportation Network Companies (TNCs) like Uber or Lyft justify frequent and p…
View article: Speakerbox: Few-Shot Learning for SpeakerIdentification with Transformers
Speakerbox: Few-Shot Learning for SpeakerIdentification with Transformers Open
Automated speaker identification is a modeling challenge for research when large-scale corpora, such as audio recordings or transcripts, are relied upon for evidence (e.g.Journalism, Qualitative Research, Law, etc.).To address current diff…
View article: Soft-Search: Two Datasets to Study the Identification and Production of Research Software
Soft-Search: Two Datasets to Study the Identification and Production of Research Software Open
Software is an important tool for scholarly work, but software produced for research is in many cases not easily identifiable or discoverable. A potential first step in linking research and software is software identification. In this pape…
View article: OME-Zarr: a cloud-optimized bioimaging file format with international community support
OME-Zarr: a cloud-optimized bioimaging file format with international community support Open
A growing community is constructing a next-generation file format (NGFF) for bioimaging to overcome problems of scalability and heterogeneity. Organized by the Open Microscopy Environment (OME), individuals and institutes across diverse mo…
View article: Integrated intracellular organization and its variations in human iPS cells
Integrated intracellular organization and its variations in human iPS cells Open
Understanding how a subset of expressed genes dictates cellular phenotype is a considerable challenge owing to the large numbers of molecules involved, their combinatorics and the plethora of cellular behaviours that they determine 1,2 . H…
View article: Mapping variation in the morphological landscape of human cells with optical pooled CRISPRi screening
Mapping variation in the morphological landscape of human cells with optical pooled CRISPRi screening Open
The contributions of individual genes to cell-scale morphology and cytoskeletal organization are challenging to define due to the wide intercellular variation of these complex phenotypes. We leveraged the controlled nature of image-based p…
View article: A deep generative model of 3D single-cell organization
A deep generative model of 3D single-cell organization Open
We introduce a framework for end-to-end integrative modeling of 3D single-cell multi-channel fluorescent image data of diverse subcellular structures. We employ stacked conditional β -variational autoencoders to first learn a latent repres…
View article: Council Data Project: Software for Municipal DataCollection, Analysis, and Publication
Council Data Project: Software for Municipal DataCollection, Analysis, and Publication Open
Cities, counties, and states throughout the USA are bound by law to archive recordings of public meetings.Most local governments comply with these laws by posting documents, audio, or video recordings online.As there is no set standard for…
View article: A deep generative model of 3D single-cell organization
A deep generative model of 3D single-cell organization Open
1 Abstract We introduce a framework for end-to-end integrative modeling of 3D single-cell multi-channel fluorescent image data of diverse subcellular structures. We employ stacked conditional β -variational autoencoders to first learn a la…
View article: Managing Manifests and Distributing Datasets
Managing Manifests and Distributing Datasets Open
Quilt3Distribute (Q3D) is a software application that enables the distribution of manifest style datasets which can be made of up thousands of individual files.
View article: Packaging Municipal Legislative Event Data for Reuse & Exchange
Packaging Municipal Legislative Event Data for Reuse & Exchange Open
Municipal governments in the USA are often divided between a legislative (city council) and executive (mayoral) branch. These two branches not only differ in their power to govern a municipality, but also in the way their governing activit…
View article: DSDB: Reproducible Computational Modeling
DSDB: Reproducible Computational Modeling Open
In the following abstract we describe Dataset-Database (DSDB), an open-source system for handling the provenance, versioning, de-duplication, history, and query of dynamic databases used at the Allen Institute for Cell Science. We present …
View article: ACE INHIBITORS AND ARBS INFLUENCE ON MOBILITY OUTCOMES IN OLDER ADULTS: RESULTS FROM THE LIFE TRIAL
ACE INHIBITORS AND ARBS INFLUENCE ON MOBILITY OUTCOMES IN OLDER ADULTS: RESULTS FROM THE LIFE TRIAL Open
Angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARBs), generally considered interchangeable in cardiovascular disease, are thought to preserve mobility throughout aging. Whether these drug classes exert d…