Eva K. Pillai
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View article: Environmental stiffness regulates neuronal maturation via Piezo1-mediated transthyretin activity
Environmental stiffness regulates neuronal maturation via Piezo1-mediated transthyretin activity Open
View article: Prioritising Sexual and Reproductive Health on a Female Inpatient Psychiatric Ward: A Quality Improvement Project
Prioritising Sexual and Reproductive Health on a Female Inpatient Psychiatric Ward: A Quality Improvement Project Open
Aims: Serious mental illness is associated with higher rates of sexual assault and gynaecological cancers, alongside pre-menstrual disorders and the menopause which can be implicated in psychiatric presentation, relapse or treatment resist…
View article: The association between relapse and the outcome of schizophrenia and recurrent psychotic disorders
The association between relapse and the outcome of schizophrenia and recurrent psychotic disorders Open
Background Having a relapse of schizophrenia or recurrent psychosis is feared by patients, can cause social and personal disruption and has been suggested to cause long-term deterioration, possibly because of a toxic biological process. Ai…
View article: Environmental stiffness regulates neuronal maturation via Piezo1-mediated TTR activity
Environmental stiffness regulates neuronal maturation via Piezo1-mediated TTR activity Open
During brain development, neurons extend axons to connect to their target cells while initiating a maturation process during which neurons start expressing voltage-gated ion channels, form synapses, express synaptic transmitters and recept…
View article: Long-range chemical signalling <i>in vivo</i> is regulated by mechanical signals
Long-range chemical signalling <i>in vivo</i> is regulated by mechanical signals Open
Biological processes are regulated by chemical and mechanical signals, yet the interaction between these signalling modalities remains poorly understood. Using the developing Xenopus laevis brain as a model system, we identified a critical…
View article: Mechanics in the nervous system: From development to disease
Mechanics in the nervous system: From development to disease Open
View article: Data set accompanying the paper "Effective cell membrane tension is independent of polyacrylamide substrate stiffness"
Data set accompanying the paper "Effective cell membrane tension is independent of polyacrylamide substrate stiffness" Open
This data set contains the data presented in the publication "Effective cell membrane tension is independent of polyacrylamide substrate stiffness". It consists of optical tweezers data and traction force microscopy data of 3T3 fibroblasts…
View article: Data set accompanying the paper "Effective cell membrane tension is independent of polyacrylamide substrate stiffness"
Data set accompanying the paper "Effective cell membrane tension is independent of polyacrylamide substrate stiffness" Open
This data set contains the data presented in the publication "Effective cell membrane tension is independent of polyacrylamide substrate stiffness". This consists of Optical Tweezers data as well as Traction Force Microscopy of 3T3 fibrobl…
View article: Data set accompanying the paper "Effective cell membrane tension is independent of polyacrylamide substrate stiffness"
Data set accompanying the paper "Effective cell membrane tension is independent of polyacrylamide substrate stiffness" Open
This data set contains the data presented in the publication "Effective cell membrane tension is independent of polyacrylamide substrate stiffness". It consists of optical tweezers data and traction force microscopy data of 3T3 fibroblasts…
View article: Effective cell membrane tension is independent of polyacrylamide substrate stiffness
Effective cell membrane tension is independent of polyacrylamide substrate stiffness Open
Most animal cells are surrounded by a cell membrane and an underlying actomyosin cortex. Both structures are linked, and they are under tension. In-plane membrane tension and cortical tension both influence many cellular processes, includi…
View article: Effective cell membrane tension is independent of polyacrylamide substrate stiffness
Effective cell membrane tension is independent of polyacrylamide substrate stiffness Open
Most animal cells are surrounded by a cell membrane and an underlying actomyosin cortex. Both structures are linked, and they are under tension. In-plane membrane tension and cortical tension both influence many cellular processes, includi…
View article: Interplay between Piezo1-mediated mechanosensing and the chemical guidance cue Semaphorin3A during development of the embryonic nervous system
Interplay between Piezo1-mediated mechanosensing and the chemical guidance cue Semaphorin3A during development of the embryonic nervous system Open
During nervous system development, growing neurons extend axons over long distances to defined targets. Despite decades of research dedicated to understanding how neurons are guided along the correct pathways, we still do not fully underst…
View article: Rapid changes in tissue mechanics regulate cell behaviour in the developing embryonic brain
Rapid changes in tissue mechanics regulate cell behaviour in the developing embryonic brain Open
Tissue mechanics is important for development; however, the spatio-temporal dynamics of in vivo tissue stiffness is still poorly understood. We here developed tiv-AFM, combining time-lapse in vivo atomic force microscopy with upright fluor…
View article: Author response: Rapid changes in tissue mechanics regulate cell behaviour in the developing embryonic brain
Author response: Rapid changes in tissue mechanics regulate cell behaviour in the developing embryonic brain Open
Article Figures and data Abstract eLife digest Main text Data availability References Decision letter Author response Article and author information Metrics Abstract Tissue mechanics is important for development; however, the spatio-tempor…
View article: Mechanosensing is critical for axon growth in the developing brain
Mechanosensing is critical for axon growth in the developing brain Open
View article: Linkage and association analysis of ADHD endophenotypes in extended and multigenerational pedigrees from a genetic isolate
Linkage and association analysis of ADHD endophenotypes in extended and multigenerational pedigrees from a genetic isolate Open