Eva-Maria Siegmann
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View article: Effects of an App-Based Mindfulness Intervention during Pregnancy on the Infant’s Prenatal Androgen Exposure: A Randomized Controlled Pilot Trial
Effects of an App-Based Mindfulness Intervention during Pregnancy on the Infant’s Prenatal Androgen Exposure: A Randomized Controlled Pilot Trial Open
Prenatal androgen exposure modulates the development of the brain, with lasting effects on its function and behavior over the infant’s life span. Environmental factors during pregnancy, in particular maternal stress, have been shown to inf…
View article: New ways to cope with depression—study protocol for a randomized controlled mixed methods trial of bouldering psychotherapy (BPT) and mental model therapy (MMT)
New ways to cope with depression—study protocol for a randomized controlled mixed methods trial of bouldering psychotherapy (BPT) and mental model therapy (MMT) Open
Background Due to the growing gap between the demand and supply of therapeutic services for people suffering from depression, with this study, we are investigating the effectiveness and factors of influence of new approaches in group treat…
View article: Reconceptualization of the Erlangen Score for the Assessment of Dementia Risk: The ERlangen Score
Reconceptualization of the Erlangen Score for the Assessment of Dementia Risk: The ERlangen Score Open
Background: The established Erlangen Score (ES) for the interpretation of cerebrospinal fluid (CSF) biomarkers in the diagnostics of Alzheimer’s disease (AD) uses markers of amyloidopathy and tauopathy, equally weighted to form an easy-int…
View article: The Effect of Digital Mindfulness Interventions on Depressive, Anxiety, and Stress Symptoms in Pregnant Women: A Systematic Review and Meta-Analysis
The Effect of Digital Mindfulness Interventions on Depressive, Anxiety, and Stress Symptoms in Pregnant Women: A Systematic Review and Meta-Analysis Open
Introduction. Pregnancy is a unique time in a woman’s life that can be both exciting and challenging. It is also a period that can be associated with significant stress, anxiety, and depression, which can have negative consequences for bot…
View article: Digit Ratio (2D:4D) Is Not Associated with Alzheimer’s Disease in the Elderly
Digit Ratio (2D:4D) Is Not Associated with Alzheimer’s Disease in the Elderly Open
The development of Alzheimer’s disease (AD) is influenced by sex hormones—estrogens and androgens in particular. However, the impact of prenatal sex hormone exposure is less clear; very few investigations have examined the relationship bet…
View article: Psychometric properties of the German Penn Alcohol Craving Scale
Psychometric properties of the German Penn Alcohol Craving Scale Open
Craving for alcohol is an important diagnostic criterion in alcohol use disorder (AUD) and an established predictor of future relapse. The 5-item Penn Alcohol Craving Scale (PACS) is one of the most widely used questionnaires to quantify c…
View article: PASSED: Brain atrophy in non-demented individuals in a long-term longitudinal study from two independent cohorts
PASSED: Brain atrophy in non-demented individuals in a long-term longitudinal study from two independent cohorts Open
Introduction Alzheimer’s disease (AD) is indicated by a decrease in amyloid beta 42 (Aβ42) level or the Aβ42/Aβ40 ratio, and by increased levels of Tau with phosphorylated threonine at position 181 (pTau181) in cerebrospinal fluid (CSF) ye…
View article: Amyloid-β levels and cognitive trajectories in non-demented pTau181-positive subjects without amyloidopathy
Amyloid-β levels and cognitive trajectories in non-demented pTau181-positive subjects without amyloidopathy Open
Phosphorylated Tau181 (pTau181) in CSF and recently in plasma has been associated with Alzheimer’s disease. In the absence of amyloidopathy, individuals with increased total Tau levels and/or temporal lobe atrophy experience no or only mil…
View article: Association of Depression and Anxiety Disorders With Autoimmune Thyroiditis
Association of Depression and Anxiety Disorders With Autoimmune Thyroiditis Open
This meta-analysis establishes the association between AIT and depression and anxiety disorders. Patients with AIT exhibit an increased chance of developing symptoms of depression and anxiety or of receiving a diagnosis of depression and a…