Éva Pállinger
YOU?
Author Swipe
View article: Pattern of Regulatory T Cells, Resident Memory T Cells, and Exhausted T Cells in Human Pericardial Fluid Samples of Cardiovascular Patients
Pattern of Regulatory T Cells, Resident Memory T Cells, and Exhausted T Cells in Human Pericardial Fluid Samples of Cardiovascular Patients Open
This study investigates T cell subsets in pericardial fluid samples obtained from heart transplantation donors, heart transplantation recipients, and coronary artery bypass graft patients. Using flow cytometry, we characterized regulatory …
View article: Comparative Study of Ferrocene- and Indene-Based Tamoxifen Derivatives of Different Molecular Flexibility on High-Mortality Cancer Cell Lines
Comparative Study of Ferrocene- and Indene-Based Tamoxifen Derivatives of Different Molecular Flexibility on High-Mortality Cancer Cell Lines Open
Tamoxifen is a well-established selective estrogen receptor modulator (SERM) widely used in breast cancer treatment, yet its efficacy varies across tumor types. To enhance its antitumor potential, we previously synthesized and investigated…
View article: Isolation and Characterization of Tissue-Derived Extracellular Vesicles from Mouse Lymph Nodes
Isolation and Characterization of Tissue-Derived Extracellular Vesicles from Mouse Lymph Nodes Open
Extracellular vesicles (EVs) are lipid membrane-enclosed particles released by all cells and can be isolated from various sources, even from solid tissues. This study focuses on isolating and characterizing EVs from mouse lymph nodes (LNs)…
View article: Effects of light exposure during IVF: transcriptomic analysis of murine embryos and embryo-derived EVs
Effects of light exposure during IVF: transcriptomic analysis of murine embryos and embryo-derived EVs Open
Introduction Light exposure of embryos during assisted reproduction affects embryo quality and implantation capacity in a wavelength dependent manner. We investigated the molecular mechanism of these light-induced changes through the compa…
View article: Proteomic analysis of plasma-derived extracellular vesicles: pre- and postprandial comparisons
Proteomic analysis of plasma-derived extracellular vesicles: pre- and postprandial comparisons Open
Extracellular vesicles (EVs) are key in intercellular communication, carrying biomolecules like nucleic acids, lipids, and proteins. This study investigated postprandial characteristics and proteomic profiles of blood-derived EVs in health…
View article: Associations between Various Inflammatory Markers and Carotid Findings in a Voluntary Asymptomatic Population Sample
Associations between Various Inflammatory Markers and Carotid Findings in a Voluntary Asymptomatic Population Sample Open
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide, and atherosclerosis is the key factor promoting its development. Carotid intima-media thickening and the presence of carotid plaques are important indi…
View article: Circulating pre- and postprandial extracellular vesicle proteomic profiles
Circulating pre- and postprandial extracellular vesicle proteomic profiles Open
Extracellular vesicles (EVs) are key in intercellular communication, carrying biomolecules like nucleic acids, lipids, and proteins. This study investigated postprandial characteristics and proteomic profiles of circulating large extracell…
View article: Effect of hypercholesterolemia on circulating and cardiomyocyte-derived extracellular vesicles
Effect of hypercholesterolemia on circulating and cardiomyocyte-derived extracellular vesicles Open
View article: Flow Cytometry-Based Assay to Detect Alpha Galactosidase Enzymatic Activity at the Cellular Level
Flow Cytometry-Based Assay to Detect Alpha Galactosidase Enzymatic Activity at the Cellular Level Open
Background: Fabry disease is a progressive, X chromosome-linked lysosomal storage disorder with multiple organ dysfunction. Due to the absence or reduced activity of alpha-galactosidase A (AGAL), glycosphingolipids, primarily globotriaosyl…
View article: Review of: "[Case Study] Targeting the Warburg Effect with the Glucose Mutation Theory: A Case Study of 36-Year-Old Female Treated for Stage IV Metastatic TPBCUsing Glucosodiene Over a 15-Day Period"
Review of: "[Case Study] Targeting the Warburg Effect with the Glucose Mutation Theory: A Case Study of 36-Year-Old Female Treated for Stage IV Metastatic TPBCUsing Glucosodiene Over a 15-Day Period" Open
Potential competing interests: No potential competing interests to declare.Cancer is one of the leading causes of death worldwide.There is increased evidence that the currently used cancer treatments, including surgery, radiation, and chem…
View article: Extracellular Vesicles of Patients on Peritoneal Dialysis Inhibit the TGF-β- and PDGF-B-Mediated Fibrotic Processes
Extracellular Vesicles of Patients on Peritoneal Dialysis Inhibit the TGF-β- and PDGF-B-Mediated Fibrotic Processes Open
Among patients on peritoneal dialysis (PD), 50–80% will develop peritoneal fibrosis, and 0.5–4.4% will develop life-threatening encapsulating peritoneal sclerosis (EPS). Here, we investigated the role of extracellular vesicles (EVs) on the…
View article: Growth and differentiation factor-15: A link between inflammaging and cardiovascular disease
Growth and differentiation factor-15: A link between inflammaging and cardiovascular disease Open
Age-related disorders are closely linked to the accumulation of senescent cells. The senescence-associated secretory phenotype (SASP) sustains and progresses chronic inflammation, which is involved in cellular and tissue dysfunction. SASP-…
View article: Recipient Pericardial Apolipoprotein Levels Might Be an Indicator of Worse Outcomes after Orthotopic Heart Transplantation
Recipient Pericardial Apolipoprotein Levels Might Be an Indicator of Worse Outcomes after Orthotopic Heart Transplantation Open
Background: End-stage heart failure (ESHF) leads to hypoperfusion and edema formation throughout the body and is accompanied by neurohormonal and immunological alterations. Orthotopic heart transplantation (HTX) has been used as a benefici…
View article: Extracellular vesicles of patients on peritoneal dialysis inhibit the TGF-β and PDGF-B mediated fibrotic processes
Extracellular vesicles of patients on peritoneal dialysis inhibit the TGF-β and PDGF-B mediated fibrotic processes Open
Background: Peritoneal fibrosis develops in 50%-80%, and life-threatening encapsulating peritoneal sclerosis (EPS) in 0.5-4.4% of the patients on peritoneal dialysis (PD). Here we investigated the role of extracellular vesicles (EVs) on th…
View article: Terhesség az immunsejtek szemszögéből
Terhesség az immunsejtek szemszögéből Open
A magzat immunológiai felismerése a sikeres terhesség feltétele. Ennek alapját a decidualizáció teremti meg, melynek révén létrejön az embrió befogadására alkalmas szöveti környezet. A decidualizáció során kialakuló speciális szövet endokr…
View article: Long-term shelf-life liposomes for delivery of prednisolone and budesonide
Long-term shelf-life liposomes for delivery of prednisolone and budesonide Open
Liposomes are nanoscale drug delivery systems built up from lipid layers and are able to spontaneously self-assemble in an aqueous environment. Both hydrophilic and hydrophobic drugs can be delivered by liposomes and this kind of nanoformu…
View article: Recipient Pericardial Apolipoprotein Levels Might Be an Indicator of Worse Outcomes after Orthotopic Heart Transplantation
Recipient Pericardial Apolipoprotein Levels Might Be an Indicator of Worse Outcomes after Orthotopic Heart Transplantation Open
End-stage heart failure (ESHF) leads to hypoperfusion and edema formation in the whole body and is accompanied by neurohormonal and immunological alterations. Orthotopic heart transplantation (HTX) has been used as a beneficial option for …
View article: Association of growth and differentiation factor-15 with coronary artery calcium score and ankle-brachial index in a middle-aged and elderly Caucasian population sample free of manifest cardiovascular disease
Association of growth and differentiation factor-15 with coronary artery calcium score and ankle-brachial index in a middle-aged and elderly Caucasian population sample free of manifest cardiovascular disease Open
View article: Ergolide Mediates Anti-Cancer Effects on Metastatic Uveal Melanoma Cells and Modulates their Cellular and Extracellular Vesicle proteomes
Ergolide Mediates Anti-Cancer Effects on Metastatic Uveal Melanoma Cells and Modulates their Cellular and Extracellular Vesicle proteomes Open
Underlying dataset and extended dataset of the results described in the article "Ergolide Mediates Anti-Cancer Effects on Metastatic Uveal Melanoma Cells and Modulates their Cellular and Extracellular Vesicle proteomes".
View article: Ergolide Mediates Anti-Cancer Effects on Metastatic Uveal Melanoma Cells and Modulates their Cellular and Extracellular Vesicle proteomes
Ergolide Mediates Anti-Cancer Effects on Metastatic Uveal Melanoma Cells and Modulates their Cellular and Extracellular Vesicle proteomes Open
Underlying dataset and extended dataset of the results described in the article "Ergolide Mediates Anti-Cancer Effects on Metastatic Uveal Melanoma Cells and Modulates their Cellular and Extracellular Vesicle proteomes".
View article: Different implantable electrospun meshes for simultaneous application of prednisone and doxorubicin
Different implantable electrospun meshes for simultaneous application of prednisone and doxorubicin Open
Electrospinning is widely applied to prepare nanofibers that provide high specific surfaces, enhanced bioavailability of poorly water-soluble drugs, moreover, enable several administration routes such as implantation. In this perspective, …
View article: Neutrophil-to-Lymphocyte Ratio Is an Independent Risk Factor for Coronary Artery Disease in Central Obesity
Neutrophil-to-Lymphocyte Ratio Is an Independent Risk Factor for Coronary Artery Disease in Central Obesity Open
Several inflammatory biomarkers were found to be associated with an increased risk of cardiovascular disease. Neutrophil-to-lymphocyte ratio (NLR) is a marker of subclinical inflammation that increases with the stress response. Visceral ad…
View article: Donor Pericardial Interleukin and Apolipoprotein Levels May Predict the Outcome after Human Orthotopic Heart Transplantation
Donor Pericardial Interleukin and Apolipoprotein Levels May Predict the Outcome after Human Orthotopic Heart Transplantation Open
The proinflammatory cascade that is activated at the time of brain death plays a crucial role in organ procurement. Our aim of this study was to explore the relationship between the clinical outcome of orthotopic heart transplantation, as …
View article: Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration
Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration Open
Tobacco smoking is strongly linked to vascular damage contributing to the development of hypertension, atherosclerosis, as well as increasing the risk for neurodegeneration. Still, the involvement of the innate immune system in the develop…
View article: Characterization of Electrospun Polysuccinimide‐Dopamine Conjugates and Effect on Cell Viability and Uptake
Characterization of Electrospun Polysuccinimide‐Dopamine Conjugates and Effect on Cell Viability and Uptake Open
Biocompatible nanofibrous systems made by electrospinning have been studied widely for pharmaceutical applications since they have a high specific surface and the capability to make the entrapped drug molecule amorphous, which increases bi…
View article: Upregulation of exofacial peroxiredoxin-thioredoxin system of lymphocytes and monocytes in preeclampsia
Upregulation of exofacial peroxiredoxin-thioredoxin system of lymphocytes and monocytes in preeclampsia Open
We have revealed that the level of advanced oxidation protein products is increased and the exofacial peroxiredoxin-1 and thioredoxin-1 system in lymphocytes and monocytes is upregulated in preeclampsia. In addition, the ratio of peroxired…
View article: A decidualizáció klinikai vonatkozásai
A decidualizáció klinikai vonatkozásai Open
A sikeres fogantatás és terhesség elengedhetetlen összetevője a decidualizáció, amely az endometrium szerkezeti és funkcionális átalakulását jelenti. A folyamat magában foglalja a méhnyálkahártya szerkezeti változásait, a spirális arteriol…
View article: Characterization of immune checkpoint inhibitor‐induced cardiotoxicity reveals interleukin‐17A as a driver of cardiac dysfunction after anti‐PD‐1 treatment
Characterization of immune checkpoint inhibitor‐induced cardiotoxicity reveals interleukin‐17A as a driver of cardiac dysfunction after anti‐PD‐1 treatment Open
Background and Purpose Immune checkpoint inhibitors (ICI), such as anti‐PD‐1 monoclonal antibodies, have revolutionized cancer therapy by enhancing the cytotoxic effects of T‐cells against tumours. However, enhanced T‐cell activity also ma…
View article: Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration
Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration Open
Tobacco smoking is strongly linked to vascular damage contributing to the development of hypertension, atherosclerosis, as well as an increased risk for neurodegeneration. Still, the contribution of the innate immune system to the developm…
View article: CD3+/CD56+ NKT-like Cells Show Imbalanced Control Immediately after Exercise in Delayed-Onset Muscle Soreness
CD3+/CD56+ NKT-like Cells Show Imbalanced Control Immediately after Exercise in Delayed-Onset Muscle Soreness Open
The purpose of the study was to carry out an immunophenotypical characterization with a special focus on natural killer cells of junior swimmers from the Hungarian National Swim Team before and after an intensive acute exercise. Nineteen s…