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View article: 67 national-level factors potentially related to the incidence of kidney replacement therapy across Europe
67 national-level factors potentially related to the incidence of kidney replacement therapy across Europe Open
Background Kidney replacement therapy (KRT) incidence varies considerably across European countries. We aimed to provide an overview of factors potentially related to KRT incidence for all individual European countries and across low, midd…
View article: Measures of wave intensity as a non-invasive surrogate for cardiac function predicts mortality in haemodialysis patients
Measures of wave intensity as a non-invasive surrogate for cardiac function predicts mortality in haemodialysis patients Open
Background Risk prediction in haemodialysis (HD) patients is challenging due to the impact of the dialysis regime on the patient's volume status and the complex interplay with cardiac function, comorbidities and hypertension. Cardiac funct…
View article: #1767 Effect of heart failure and atrial fibrillation on cardiorespiratory fitness in hemodialysis patients
#1767 Effect of heart failure and atrial fibrillation on cardiorespiratory fitness in hemodialysis patients Open
Background and Aims Heart failure (HF) and atrial fibrillation (AF) are highly prevalent in hemodialysis. They are well-known significant modifiers of the disease associations with cardiovascular outcomes, but there is a lack of evidence r…
View article: #1555 The effects of different interdialytic intervals on cardiorespiratory fitness assessed with CPET in hemodialysis patients
#1555 The effects of different interdialytic intervals on cardiorespiratory fitness assessed with CPET in hemodialysis patients Open
Background and Aims Long interdialytic interval in thrice-weekly hemodialysis is associated with excess cardiovascular and all-cause mortality risk. Impaired cardiorespiratory fitness is a strong predictor of mortality in hemodialysis. Thi…
View article: Different Interdialytic Intervals and Cardiorespiratory Fitness in Patients Undergoing Hemodialysis
Different Interdialytic Intervals and Cardiorespiratory Fitness in Patients Undergoing Hemodialysis Open
Key Points This is the first study exploring differences in cardiorespiratory fitness assessed with cardiopulmonary exercise testing between the 2-day and the 3-day interdialytic interval. The 3-day interdialytic interval was associated wi…
View article: Uromodulin biology
Uromodulin biology Open
Uromodulin is a kidney-specific glycoprotein which is exclusively produced by the epithelial cells lining the thick ascending limb and early distal convoluted tubule. It is currently recognized as a multifaceted player in kidney physiology…
View article: Cardiorespiratory fitness assessed with cardiopulmonary exercise testing in patients with juvenile idiopathic arthritis: a systematic review and meta-analysis
Cardiorespiratory fitness assessed with cardiopulmonary exercise testing in patients with juvenile idiopathic arthritis: a systematic review and meta-analysis Open
Objectives JIA is the most common type of arthritis in children and adolescents, causing joint damage, chronic pain and disability. Deconditioning is also prevalent in patients with JIA due to both inactivity and the disease progression, r…
View article: #6355 EFFECTS OF SODIUM-GLUCOSE CO-TRANSPORTER 2 INHIBITORS ON HEART FAILURE IN CHRONIC KIDNEYDISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS
#6355 EFFECTS OF SODIUM-GLUCOSE CO-TRANSPORTER 2 INHIBITORS ON HEART FAILURE IN CHRONIC KIDNEYDISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS Open
Background and Aims Sodium-glucose co-transporter 2 (SGLT-2) inhibitors significantly reduce the risk for hospitalizations for heart failure (HF) in patients with diabetes, and HF; findings in patients with chronic kidney disease (CKD) are…
View article: #3042 AMBULATORY BLOOD PRESSURE LEVELS AFFECT THE ASSOCIATION OF INTRADIALYTIC HYPERTENSION WITH ADVERSE CARDIOVASCULAR EVENTS IN HEMODIALYSIS PATIENTS
#3042 AMBULATORY BLOOD PRESSURE LEVELS AFFECT THE ASSOCIATION OF INTRADIALYTIC HYPERTENSION WITH ADVERSE CARDIOVASCULAR EVENTS IN HEMODIALYSIS PATIENTS Open
Background and Aims Patients with intradialytic hypertension (IDH) display also higher ambulatory blood pressure (BP) levels during the whole 44-h interdialytic interval compared to patients without the phenomenon. Sustained high 44-h ambu…
View article: #3075 EFFECT OF KIDNEY TRANSPLANTATION ON CARDIORESPIRATORY FITNESS ASSESSED WITH CARDIOPULMONARY EXERCISE TESTING: A SYSTEMATIC REVIEW AND META-ANALYSIS
#3075 EFFECT OF KIDNEY TRANSPLANTATION ON CARDIORESPIRATORY FITNESS ASSESSED WITH CARDIOPULMONARY EXERCISE TESTING: A SYSTEMATIC REVIEW AND META-ANALYSIS Open
Background and Aims Patients with kidney failure often present with reduced functional cardiovascular reserve and exercise intolerance. Kidney transplantation is the optimal treatment for patients with end-stage kidney disease as it is ass…
View article: #5805 ACCURACY OF FIXED 24-H AMBULATORY BLOOD PRESSURE RECORDINGS FOR DIAGNOSING HIGH 48-H AMBULATORY BLOOD PRESSURE IN HEMODIALYSIS PATIENTS
#5805 ACCURACY OF FIXED 24-H AMBULATORY BLOOD PRESSURE RECORDINGS FOR DIAGNOSING HIGH 48-H AMBULATORY BLOOD PRESSURE IN HEMODIALYSIS PATIENTS Open
Background and Aims Hypertension is highly prevalent in hemodialysis patients. Ambulatory-BP-monitoring (ABPM) during the 44-h interdialytic interval is recommended for hypertension diagnosis and management in these subjects. This study as…
View article: #6379 EFFECTS OF SODIUM-GLUCOSE CO-TRANSPORTER 2 INHIBITORS ON CARDIOVASCULAR MORTALITY INCHRONIC KIDNEY DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS
#6379 EFFECTS OF SODIUM-GLUCOSE CO-TRANSPORTER 2 INHIBITORS ON CARDIOVASCULAR MORTALITY INCHRONIC KIDNEY DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS Open
Background and Aims In studies of patients with chronic kidney disease (CKD), recommended nephroprotective therapy with ACE-inhibitors or ARBs has not been shown to reduce cardiovascular (CV) events or mortality. Sodium-glucose co-transpor…
View article: #5632 THE CLINICAL AND ECONOMIC BURDEN OF CHRONIC KIDNEY DISEASE IN GREECE
#5632 THE CLINICAL AND ECONOMIC BURDEN OF CHRONIC KIDNEY DISEASE IN GREECE Open
Background and Aims Chronic Kidney Disease (CKD) is a progressive disorder with a substantial clinical and economic burden. This burden is expected to grow, mainly because of the ageing population, and the increasing incidence of diabetes …
View article: Kidney transplantation and kidney donation do not affect short-term blood pressure variability
Kidney transplantation and kidney donation do not affect short-term blood pressure variability Open
Short-term BPV did not change significantly 3 and 12 months after kidney transplantation/donation neither in KTRs nor in living kidney donors. Longitudinal studies examining associations of BPV with adverse outcomes in these individuals ar…
View article: Effect of kidney transplantation on indices of cardiorespiratory fitness assessed with cardiopulmonary exercise testing: a systematic review and meta-analysis
Effect of kidney transplantation on indices of cardiorespiratory fitness assessed with cardiopulmonary exercise testing: a systematic review and meta-analysis Open
Patients with kidney failure often present with reduced cardiovascular reserve. Kidney transplantation (KT) is the optimal treatment for patients with end-stage kidney disease as it is associated with longer survival and improved quality o…
View article: Two Cases of Autoimmune Thyroid Disorders after COVID Vaccination in Dialysis Patients
Two Cases of Autoimmune Thyroid Disorders after COVID Vaccination in Dialysis Patients Open
SARS-CoV-2 infection and vaccination have been associated with autoimmune thyroid dysfunctions. Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) and molecular mimicry have been referred to as potential causes. Such a case has n…
View article: Ambulatory blood pressure trajectories and blood pressure variability in kidney transplant recipients: a comparative study against chronic kidney disease patients
Ambulatory blood pressure trajectories and blood pressure variability in kidney transplant recipients: a comparative study against chronic kidney disease patients Open
Background: Hypertension is a major cardiovascular risk factor in both kidney transplant recipients (KTRs) and patients with chronic kidney disease (CKD). Ambulatory blood pressure monitoring (ABPM) is considered the gold-standard method f…
View article: De novo Minimal Change Disease in an Adolescent after Pfizer-BioNTech COVID-19 Vaccination: A Case Report
De novo Minimal Change Disease in an Adolescent after Pfizer-BioNTech COVID-19 Vaccination: A Case Report Open
This is the first report in an adolescent of minimal change disease (MCD) after the first injection of the BNT162b2 COVID-19 vaccine (Pfizer-BioNTech) with complete remission following steroid treatment. An 18-year-old white male with no p…
View article: Ambulatory blood pressure trajectories and blood pressure variability in kidney transplant recipients: a comparative study against haemodialysis patients
Ambulatory blood pressure trajectories and blood pressure variability in kidney transplant recipients: a comparative study against haemodialysis patients Open
Background Hypertension is the most prevalent cardiovascular risk factor in kidney transplant recipients (KTRs). Preliminary data suggest similar ambulatory blood pressure (BP) levels in KTRs and haemodialysis (HD) patients. This is the fi…
View article: Effects of different exercise programs on the cardiorespiratory reserve in HFpEF patients: a systematic review and meta-analysis
Effects of different exercise programs on the cardiorespiratory reserve in HFpEF patients: a systematic review and meta-analysis Open
HFpEF represents a heterogeneous syndrome with complex pathophysiological substrates and multiple clinical manifestations. Recently, much attention has been focused on cardiac rehabilitation programs for HFpEF patients, and several studies…
View article: Assessment of Exercise Intolerance in Patients with Pre-Dialysis CKD with Cardiopulmonary Function Testing: Translation to Everyday Practice
Assessment of Exercise Intolerance in Patients with Pre-Dialysis CKD with Cardiopulmonary Function Testing: Translation to Everyday Practice Open
Background: Chronic kidney disease (CKD) is often characterized by increased prevalence of cardiovascular risk factors and increased incidence of cardiovascular events and death. Reduced cardiovascular reserve and exercise intolerance are …
View article: P0312ALTERATIONS IN THE PROGRESS OF LYMPHOCYTE APOPTOSIS IN PRE- AND POST- DIALYSIS END STAGE RENAL DISEASE PATIENTS
P0312ALTERATIONS IN THE PROGRESS OF LYMPHOCYTE APOPTOSIS IN PRE- AND POST- DIALYSIS END STAGE RENAL DISEASE PATIENTS Open
Background and Aims Lymphocyte apoptosis, as a programmed mechanism of lymphocyte death, is essential in maintaining homeostasis and balance between inflammatory and immune reactions. Disturbances in the apoptotic progress, leading to frag…
View article: Supplementary Material for: Ambulatory Blood Pressure Trajectories and Blood Pressure Variability in Diabetic and Non-Diabetic Chronic Kidney Disease
Supplementary Material for: Ambulatory Blood Pressure Trajectories and Blood Pressure Variability in Diabetic and Non-Diabetic Chronic Kidney Disease Open
Background: Diabetic kidney disease is the leading cause of end-stage renal disease worldwide. Whether diabetes mellitus (DM) is an additional factor leading to elevated blood pressure (BP) levels and BP variability (BPV) in patients with …