Éva Pintye
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View article: The BACH1–HMOX1 Regulatory Axis Is Indispensable for Proper Macrophage Subtype Specification and Skeletal Muscle Regeneration
The BACH1–HMOX1 Regulatory Axis Is Indispensable for Proper Macrophage Subtype Specification and Skeletal Muscle Regeneration Open
The infiltration and subsequent in situ subtype specification of monocytes to effector/inflammatory and repair macrophages is indispensable for tissue repair upon acute sterile injury. However, the chromatin-level mediators and regulatory …
View article: <i>In situ</i> macrophage phenotypic transition is affected by altered cellular composition prior to acute sterile muscle injury
<i>In situ</i> macrophage phenotypic transition is affected by altered cellular composition prior to acute sterile muscle injury Open
Key points The in situ phenotypic switch of macrophages is delayed in acute injury following irradiation. The combination of bone marrow transplantation and local muscle radiation protection allows for the identification of a myeloid cell …