Éva Rumpler
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View article: Comparing Strategies to Introduce Two New Antibiotics for Gonorrhea: A Modeling Study
Comparing Strategies to Introduce Two New Antibiotics for Gonorrhea: A Modeling Study Open
Introduction Drug resistance in Neisseria gonorrhoeae is an urgent public health threat. The anticipated approval of two new antimicrobials for gonorrhea prompts the need for evidence-based rollout strategies that minimize drug resistance.…
View article: Estrogen-Regulated Lateral Septal Kisspeptin Neurons Abundantly Project to GnRH Neurons and the Hypothalamic Supramammillary Nucleus
Estrogen-Regulated Lateral Septal Kisspeptin Neurons Abundantly Project to GnRH Neurons and the Hypothalamic Supramammillary Nucleus Open
While hypothalamic kisspeptin (KP) neurons play well-established roles in the estrogen-dependent regulation of reproduction, little is known about extrahypothalamic KP-producing (KP LS ) neurons of the lateral septum. As established previo…
View article: Equity considerations in COVID-19 vaccine allocation modelling: a literature review
Equity considerations in COVID-19 vaccine allocation modelling: a literature review Open
We conducted a literature review of COVID-19 vaccine allocation modelling papers, specifically looking for publications that considered equity. We found that most models did not take equity into account, with the vast majority of publicati…
View article: Impact of treating chronic hepatitis C with direct acting antivirals on health-related quality of life: a real-life Egyptian experience
Impact of treating chronic hepatitis C with direct acting antivirals on health-related quality of life: a real-life Egyptian experience Open
Background Chronic hepatitis C virus (HCV) infection negatively impacts health-related quality of life (HRQL). We aimed to assess patient-reported outcomes (PROs) to evaluate the impact of treating chronic HCV with directly acting antivira…
View article: Estrogen-dependent development and transcriptome regulation of the lateral septal kisspeptin system
Estrogen-dependent development and transcriptome regulation of the lateral septal kisspeptin system Open
While hypothalamic kisspeptin (KP) neurons play well-established roles in puberty and reproduction, kisspeptin neurons in the lateral septum (KP LS neurons) and other extrahypothalamic sites have received less attention. We found that the …
View article: Out-of-pocket expenditures and financial risks associated with treatment of vaccine-preventable diseases in Ethiopia: A cross-sectional costing analysis
Out-of-pocket expenditures and financial risks associated with treatment of vaccine-preventable diseases in Ethiopia: A cross-sectional costing analysis Open
Background Vaccine-preventable diseases (VPDs) remain major causes of morbidity and mortality in low- and middle-income countries (LMICs). Universal access to vaccination, besides improved health outcomes, would substantially reduce VPD-re…
View article: Fairness and efficiency considerations in COVID-19 vaccine allocation strategies: A case study comparing front-line workers and 65–74 year olds in the United States
Fairness and efficiency considerations in COVID-19 vaccine allocation strategies: A case study comparing front-line workers and 65–74 year olds in the United States Open
The COVID-19 epidemic in the United States has been characterized by two stark disparities. COVID-19 burden has been unequally distributed among racial and ethnic groups and at the same time the mortality rates have been sharply higher amo…
View article: Comparative performance of between-population vaccine allocation strategies with applications for emerging pandemics
Comparative performance of between-population vaccine allocation strategies with applications for emerging pandemics Open
To examine optimal vaccine allocation decisions across population considering the impact of characteristics of the population, vaccine pathogen, and delivery.
View article: Modeling the relative risk of incidence and mortality of select vaccine-preventable diseases by wealth group and geographic region in Ethiopia
Modeling the relative risk of incidence and mortality of select vaccine-preventable diseases by wealth group and geographic region in Ethiopia Open
Immunization is one of the most effective public health interventions, saving millions of lives every year. Ethiopia has seen gradual improvements in immunization coverage and access to child health care services; however, inequalities in …
View article: Methods for early characterisation of the severity and dynamics of SARS-CoV-2 variants: a population-based time series analysis in South Africa
Methods for early characterisation of the severity and dynamics of SARS-CoV-2 variants: a population-based time series analysis in South Africa Open
National Institute for Communicable Diseases of South Africa, South African National Government.
View article: Infectious disease dynamics and restrictions on social gathering size
Infectious disease dynamics and restrictions on social gathering size Open
To develop a model for transmission of SARS-CoV-2 during social gatherings and understand the effects of gathering size restrictions on outbreak dynamics
View article: Fairness and efficiency considerations in COVID-19 vaccine allocation strategies: a case study comparing front-line workers and 65-74 year olds in the United States
Fairness and efficiency considerations in COVID-19 vaccine allocation strategies: a case study comparing front-line workers and 65-74 year olds in the United States Open
1 Abstract The COVID-19 epidemic in the United States has been characterized by two stark disparities. COVID-19 burden has been unequally distributed among racial and ethnic groups and at the same time the mortality rates have been sharply…
View article: Infectious disease dynamics and restrictions on social gathering size
Infectious disease dynamics and restrictions on social gathering size Open
Social gatherings can be an important locus of transmission for many pathogens including SARS-CoV-2. During an outbreak, restricting the size of these gatherings is one of several non-pharmaceutical interventions available to policy-makers…
View article: Comparative performance of between-population vaccine allocation strategies with applications for emerging pandemics
Comparative performance of between-population vaccine allocation strategies with applications for emerging pandemics Open
2 Abstract Vaccine allocation decisions during emerging pandemics have proven to be challenging due to competing ethical, practical, and political considerations. Complicating decision making, policy makers need to consider vaccine allocat…
View article: Maternal Age at First Childbirth and Geographical Variation in Hepatitis B Virus Prevalence in Cameroon: Important Role of Mother-to-Child Transmission
Maternal Age at First Childbirth and Geographical Variation in Hepatitis B Virus Prevalence in Cameroon: Important Role of Mother-to-Child Transmission Open
Background The prevalence of hepatitis B virus (HBV) infection varies geographically around the world. Yet, its underlying mechanisms are unknown. Using a nationally representative population-based sample from all 58 administrative divisio…
View article: How to detect and reduce potential sources of biases in epidemiologic studies of SARS-CoV-2
How to detect and reduce potential sources of biases in epidemiologic studies of SARS-CoV-2 Open
In response to the coronavirus disease (COVID-19) pandemic, public health scientists have produced a large and rapidly expanding body of literature that aims to answer critical questions, such as the proportion of the population in a geogr…
View article: Mortality in children with sickle cell disease in mainland France from 2000 to 2015
Mortality in children with sickle cell disease in mainland France from 2000 to 2015 Open
Mortality in children with sickle cell disease in mainland France from 2000 to 2015*Were excluded patients with unknown immunization status (n=17) or patients not eligible (n=14) i.e children born before 2000 (date of licensing of PCV7) or…
View article: PF738 MORTALITY IN CHILDREN WITH SICKLE CELL DISEASE IN METROPOLITAN FRANCE FROM 2000 TO 2015
PF738 MORTALITY IN CHILDREN WITH SICKLE CELL DISEASE IN METROPOLITAN FRANCE FROM 2000 TO 2015 Open
Background: Sickle cell disease (SCD) is the most frequent genetic disease screened at birth in France. In developed countries, there has been a spectacular drop of the mortality rate during childhood. This progress has been achieved with …