Eva Sanchez-Quant
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View article: Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge
Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge Open
View article: High-calorie diets uncouple hypothalamic oxytocin neurons from a gut-to-brain satiation pathway via κ-opioid signaling
High-calorie diets uncouple hypothalamic oxytocin neurons from a gut-to-brain satiation pathway via κ-opioid signaling Open
View article: Additional file 3 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge
Additional file 3 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge Open
Additional file 3: Table S2. Marker genes.
View article: Additional file 6 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge
Additional file 6 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge Open
Additional file 6: Table S5. Differential expression Cocktail vs. DMSO.
View article: Additional file 11 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge
Additional file 11 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge Open
Additional file 11: Table S10. Drug Cocktail preparation
View article: Additional file 9 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge
Additional file 9 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge Open
Additional file 9: Table S8. Differential expression FFA+Cocktail vs. DMSO.
View article: Additional file 10 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge
Additional file 10 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge Open
Additional file 10: Table S9. Genes up-regulated upon Cocktail with and without FFA.
View article: Additional file 5 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge
Additional file 5 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge Open
Additional file 5: Table S4. Unique DEGs per subgroup upon Cocktail.
View article: Additional file 4 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge
Additional file 4 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge Open
Additional file 4: Table S3. ChEA3 results per subgroup.
View article: Additional file 2 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge
Additional file 2 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge Open
Additional file 2: Table S1. Metadata donors.
View article: Additional file 8 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge
Additional file 8 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge Open
Additional file 8: Table S7. Differential expression FFA vs. DMSO.
View article: Additional file 7 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge
Additional file 7 of Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge Open
Additional file 7: Table S6. Significance levels coefficient of variation
View article: Coupling of oxytocin and cholecystokinin pathways in the hypothalamus is required for gut-to-brain homeostatic feeding control
Coupling of oxytocin and cholecystokinin pathways in the hypothalamus is required for gut-to-brain homeostatic feeding control Open
Summary Oxytocin-expressing paraventricular hypothalamic neurons (PVN OT neurons) integrate afferent signals from the gut including cholecystokinin (CCK) to adjust whole-body energy homeostasis. However, the molecular underpinnings by whic…
View article: Single-cell metabolic profiling reveals subgroups of primary human hepatocytes showing heterogeneous responses to drug challenge
Single-cell metabolic profiling reveals subgroups of primary human hepatocytes showing heterogeneous responses to drug challenge Open
Xenobiotics are primarily metabolized by hepatocytes in the liver, and primary human hepatocytes (PHHs) are the gold standard model for the assessment of drug efficacy, safety and toxicity in the early phases of drug development. Recent ad…
View article: Coupling of Oxytocin and Cholecystokinin Pathways in the Hypothalamus is Required for Gut-to-Brain Homeostatic Feeding Control
Coupling of Oxytocin and Cholecystokinin Pathways in the Hypothalamus is Required for Gut-to-Brain Homeostatic Feeding Control Open
View article: Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation
Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation Open
View article: Arabidopsis ALIX Regulates Stomatal Aperture and Turnover of Abscisic Acid Receptors
Arabidopsis ALIX Regulates Stomatal Aperture and Turnover of Abscisic Acid Receptors Open
The plant endosomal trafficking pathway controls the abundance of membrane-associated soluble proteins, as shown for abscisic acid (ABA) receptors of the PYRABACTIN RESISTANCE1/PYR1-LIKE/REGULATORY COMPONENTS OF ABA RECEPTORS (PYR/PYL/RCAR…
View article: Publisher Correction: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes
Publisher Correction: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes Open
View article: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes Open
View article: Periodized low protein-high carbohydrate diet confers potent, but transient, metabolic improvements
Periodized low protein-high carbohydrate diet confers potent, but transient, metabolic improvements Open