Evan P. Gallagher
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View article: A Note on the Honey Bee Parasitic Phorid Fly (Apocephalus borealis Brues) in an Urban Ecosystem
A Note on the Honey Bee Parasitic Phorid Fly (Apocephalus borealis Brues) in an Urban Ecosystem Open
The honey bee is a crucial pollinator in urban ecosystems but faces multiple challenges, including habitat degradation, pollution, and parasitism by species such as the phorid fly, Apocephalus borealis Brues (Diptera: Phoridae). This study…
View article: A sense of place: Pink salmon use a magnetic map for orientation
A sense of place: Pink salmon use a magnetic map for orientation Open
The use of “map-like” information from Earth's magnetic field for orientation has been shown in diverse taxa, but questions remain regarding the function of such maps. We used a “magnetic displacement” experiment to demonstrate that juveni…
View article: CRISPR-Generated Nrf2a Loss- and Gain-of-Function Mutants Facilitate Mechanistic Analysis of Chemical Oxidative Stress-Mediated Toxicity in Zebrafish
CRISPR-Generated Nrf2a Loss- and Gain-of-Function Mutants Facilitate Mechanistic Analysis of Chemical Oxidative Stress-Mediated Toxicity in Zebrafish Open
The transcription factor Nrf2a induces a cellular antioxidant response and provides protection against chemical-induced oxidative stress, as well as playing a critical role in development and disease. Zebrafish are a powerful model to stud…
View article: Review of and Recommendations for Monitoring Contaminants and their Effects in the San Francisco Bay−Delta
Review of and Recommendations for Monitoring Contaminants and their Effects in the San Francisco Bay−Delta Open
Legacy and current-use contaminants enter into and accumulate throughout the San Francisco Bay−Delta (Bay−Delta), and are present at concentrations with known effects on species important to this diverse watershed. There remains major unce…
View article: Kinetics of Glutathione Depletion and Antioxidant Gene Expression as Indicators of Chemical Modes of Action Assessed <i>in Vitro</i> in Mouse Hepatocytes with Enhanced Glutathione Synthesis
Kinetics of Glutathione Depletion and Antioxidant Gene Expression as Indicators of Chemical Modes of Action Assessed <i>in Vitro</i> in Mouse Hepatocytes with Enhanced Glutathione Synthesis Open
Here we report a vertically integrated in vitro - in silico study that aims to elucidate the molecular initiating events involved in the induction of oxidative stress (OS) by seven diverse chemicals (cumene hydroperoxide, t-butyl hydropero…
View article: The safer chemical design game. Gamification of green chemistry and safer chemical design concepts for high school and undergraduate students
The safer chemical design game. Gamification of green chemistry and safer chemical design concepts for high school and undergraduate students Open
Green chemistry can strongly attract students to chemistry. We, therefore, developed a green chemistry educational game that motivates students at the undergraduate and advanced high school levels to consider green chemistry and sustainabi…
View article: Elevated carbon dioxide alters neural signaling and anti-predator behaviors in ocean phase coho salmon (Oncorhynchus kisutch)
Elevated carbon dioxide alters neural signaling and anti-predator behaviors in ocean phase coho salmon (Oncorhynchus kisutch) Open
Elevated levels of CO2 have been shown to disrupt numerous neurological sensory systems in marine fish. This is of concern as Pacific salmon rely heavily on an important neurosensory system for survival, the olfactory system. In this study…
View article: The Molecular Design Research Network
The Molecular Design Research Network Open
Herein, we provide an overview of a research network that is aimed at fostering interdisciplinary collaboration between chemists and toxicologists with the goal of rationally designing safer commercial chemicals. The collaborative is the M…
View article: A targeted gene expression platform allows for rapid analysis of chemical-induced antioxidant mRNA expression in zebrafish larvae
A targeted gene expression platform allows for rapid analysis of chemical-induced antioxidant mRNA expression in zebrafish larvae Open
Chemical-induced oxidative stress and the biochemical pathways that protect against oxidative damage are of particular interest in the field of toxicology. To rapidly identify oxidative stress-responsive gene expression changes in zebrafis…
View article: From the Cover: Cadmium Exposure Differentially Alters Odorant-Driven Behaviors and Expression of Olfactory Receptors in Juvenile Coho Salmon<i>(Oncorhynchus kisutch)</i>
From the Cover: Cadmium Exposure Differentially Alters Odorant-Driven Behaviors and Expression of Olfactory Receptors in Juvenile Coho Salmon<i>(Oncorhynchus kisutch)</i> Open
Salmon exposed to waterborne metals can experience olfactory impairment leading to disrupted chemosensation. In the current study, we investigated the effects of cadmium (Cd) on salmon olfactory function by modeling an exposure scenario wh…
View article: Dual NRF2 paralogs in Coho salmon and their antioxidant response element targets
Dual NRF2 paralogs in Coho salmon and their antioxidant response element targets Open
The transcription factor NFE2L2 (Nuclear Factor, Erythroid 2-Like 2, or NRF2) plays a key role in maintaining the redox state within cells. Characterization of this pathway has extended to fish, most notably zebrafish (Danio rerio), in whi…
View article: Olfactory Transcriptional Analysis of Salmon Exposed to Mixtures of Chlorpyrifos and Malathion Reveal Novel Molecular Pathways of Neurobehavioral Injury
Olfactory Transcriptional Analysis of Salmon Exposed to Mixtures of Chlorpyrifos and Malathion Reveal Novel Molecular Pathways of Neurobehavioral Injury Open
Pacific salmon exposed to sublethal concentrations of organophosphate pesticides (OP) have impaired olfactory function that can lead to loss of behaviors that are essential for survival. These exposures often involve mixtures and can occur…