Evan Korade
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View article: Activation of SIRT6 Deacetylation by DNA Strand Breaks
Activation of SIRT6 Deacetylation by DNA Strand Breaks Open
SIRT6 is an emerging regulator of longevity. Overexpression of SIRT6 extends the lifespan of mice. Conversely, SIRT6 knockout mice demonstrate severe metabolic defects and a shortened lifespan. The discrepancy between SIRT6's weak in vitro…