Evan Lewis
YOU?
Author Swipe
View article: Ethanol self-administration reduced the efficacy of a behavioral intervention to decrease cocaine choice in socially housed male and female monkeys
Ethanol self-administration reduced the efficacy of a behavioral intervention to decrease cocaine choice in socially housed male and female monkeys Open
In the clinical population, cocaine is frequently used sequentially or simultaneously with alcohol, and this pattern is linked to poorer treatment outcomes for cocaine use disorder (CUD). Yet, the impact of ethanol on cocaine reinforcement…
View article: ‘Functional mushrooms saved my daughter’s Life’: A preliminary mixed methods survey study of Reishi (Ganoderma lucidum) and lion’s mane (Hericium erinaceus) for epilepsy
‘Functional mushrooms saved my daughter’s Life’: A preliminary mixed methods survey study of Reishi (Ganoderma lucidum) and lion’s mane (Hericium erinaceus) for epilepsy Open
View article: 19 patients report seizure freedom with medical cannabis oil treatment for drug-resistant epilepsy: a case series
19 patients report seizure freedom with medical cannabis oil treatment for drug-resistant epilepsy: a case series Open
Purpose Seizure freedom (SF) is the primary goal of epilepsy treatment. More treatments that produce SF in drug-resistant epilepsy (DRE) are needed. Cannabis-based products for medicinal use (CBPMs) containing cannabidiol (CBD) and Δ9-tetr…
View article: A multi-centre, tolerability study of a cannabidiol-enriched Cannabis Herbal Extract for chronic headaches in adolescents: The CAN-CHA protocol
A multi-centre, tolerability study of a cannabidiol-enriched Cannabis Herbal Extract for chronic headaches in adolescents: The CAN-CHA protocol Open
Introduction Cannabis products have been used in the management of headaches in adults and may play a role in pediatric chronic pain. Canadian pediatricians report increasing use of cannabis for the management of chronic headaches, despite…
View article: <scp>IRF2BPL</scp>‐Related Disorder, Causing Neurodevelopmental Disorder with Regression, Abnormal Movements, Loss of Speech and Seizures (<scp>NEDAMSS</scp>) Is Characterized by Pathology Consistent with <scp>DRPLA</scp>
<span>IRF2BPL</span>‐Related Disorder, Causing Neurodevelopmental Disorder with Regression, Abnormal Movements, Loss of Speech and Seizures (<span>NEDAMSS</span>) Is Characterized by Pathology Consistent with <span>DRPLA</span> Open
Background Childhood neurodegenerative diseases often pose a challenge to clinicians to diagnose because of the degree of genetic heterogeneity and variable presentations. Here, we present a child with progressive neurodegeneration consist…
View article: Exploring psychedelic-assisted therapy in the treatment of functional seizures: A review of underlying mechanisms and associated brain networks
Exploring psychedelic-assisted therapy in the treatment of functional seizures: A review of underlying mechanisms and associated brain networks Open
Functional seizures (FS), the most common subtype of functional neurological disorder (FND), cause serious neurological disability and significantly impact quality of life. Characterized by episodic disturbances of functioning that resembl…
View article: Psychedelics, epilepsy, and seizures: a review
Psychedelics, epilepsy, and seizures: a review Open
Psychedelic compounds have been utilized by humans for centuries for medicinal, religious, and tribal purposes. Clinical trial data starting from the early 2000s and continuing today indicates that psychedelics are a clinically efficacious…
View article: A Multi-Centre, Tolerability Study of a Cannabidiol-enriched Cannabis Herbal Extract for Chronic Headaches in Adolescents: the CAN-CHA Protocol
A Multi-Centre, Tolerability Study of a Cannabidiol-enriched Cannabis Herbal Extract for Chronic Headaches in Adolescents: the CAN-CHA Protocol Open
Introduction Cannabis products have been used in the management of headaches in adults and may play a role in pediatric chronic pain. Canadian pediatricians report increasing use of cannabis for the management of chronic headaches, despite…
View article: Development of an online calculator for the prediction of seizure freedom following pediatric hemispherectomy using the Hemispherectomy Outcome Prediction Scale (HOPS)
Development of an online calculator for the prediction of seizure freedom following pediatric hemispherectomy using the Hemispherectomy Outcome Prediction Scale (HOPS) Open
Objectives Although hemispheric surgeries are among the most effective procedures for drug‐resistant epilepsy (DRE) in the pediatric population, there is a large variability in seizure outcomes at the group level. A recently developed HOPS…
View article: Case report: Improvement in refractory functional seizures, depression, and quality of life with ketamine-assisted therapy
Case report: Improvement in refractory functional seizures, depression, and quality of life with ketamine-assisted therapy Open
Functional seizures, a primary subtype of functional neurological disorder (FND), are a known cause of serious neurological disability with an increasing awareness of their impact amongst the neuroscience community. Situated at the interse…
View article: Legends to Supplementary Figures from Antitumor Activity of a Kinesin Inhibitor
Legends to Supplementary Figures from Antitumor Activity of a Kinesin Inhibitor Open
Legends to Supplementary Figures from Antitumor Activity of a Kinesin Inhibitor
View article: Supplementary Fig. 2 from Antitumor Activity of a Kinesin Inhibitor
Supplementary Fig. 2 from Antitumor Activity of a Kinesin Inhibitor Open
Supplementary Fig. 2 from Antitumor Activity of a Kinesin Inhibitor
View article: Supplementary Fig. 3 from Antitumor Activity of a Kinesin Inhibitor
Supplementary Fig. 3 from Antitumor Activity of a Kinesin Inhibitor Open
Supplementary Fig. 3 from Antitumor Activity of a Kinesin Inhibitor
View article: Data from Antitumor Activity of a Kinesin Inhibitor
Data from Antitumor Activity of a Kinesin Inhibitor Open
Several members of the kinesin family of microtubule motor proteins play essential roles in mitotic spindle function and are potential targets for the discovery of novel antimitotic cancer therapies. KSP, also known as HsEg5, is a k…
View article: Legends to Supplementary Figures from Antitumor Activity of a Kinesin Inhibitor
Legends to Supplementary Figures from Antitumor Activity of a Kinesin Inhibitor Open
Legends to Supplementary Figures from Antitumor Activity of a Kinesin Inhibitor
View article: Supplementary Fig. 3 from Antitumor Activity of a Kinesin Inhibitor
Supplementary Fig. 3 from Antitumor Activity of a Kinesin Inhibitor Open
Supplementary Fig. 3 from Antitumor Activity of a Kinesin Inhibitor
View article: Supplementary Fig. 2 from Antitumor Activity of a Kinesin Inhibitor
Supplementary Fig. 2 from Antitumor Activity of a Kinesin Inhibitor Open
Supplementary Fig. 2 from Antitumor Activity of a Kinesin Inhibitor
View article: Data from Antitumor Activity of a Kinesin Inhibitor
Data from Antitumor Activity of a Kinesin Inhibitor Open
Several members of the kinesin family of microtubule motor proteins play essential roles in mitotic spindle function and are potential targets for the discovery of novel antimitotic cancer therapies. KSP, also known as HsEg5, is a k…
View article: Supplementary Fig. 1 from Antitumor Activity of a Kinesin Inhibitor
Supplementary Fig. 1 from Antitumor Activity of a Kinesin Inhibitor Open
Supplementary Fig. 1 from Antitumor Activity of a Kinesin Inhibitor
View article: Supplementary Fig. 1 from Antitumor Activity of a Kinesin Inhibitor
Supplementary Fig. 1 from Antitumor Activity of a Kinesin Inhibitor Open
Supplementary Fig. 1 from Antitumor Activity of a Kinesin Inhibitor
View article: Persons With Spinal Cord Injury Report Peripherally Dominant Serotonin-Like Syndrome After Use of Serotonergic Psychedelics
Persons With Spinal Cord Injury Report Peripherally Dominant Serotonin-Like Syndrome After Use of Serotonergic Psychedelics Open
Psychedelic-assisted therapy (PAT) may treat various mental health conditions. Despite its promising therapeutic signal across mental health outcomes, less attention is paid on its potential to provide therapeutic benefits across complex m…
View article: Letter to the editor on “Geotemporospatial and causal inferential epidemiological overview and survey of USA cannabis, cannabidiol and cannabinoid genotoxicity expressed in cancer incidence 2003–2017, parts 1–3”
Letter to the editor on “Geotemporospatial and causal inferential epidemiological overview and survey of USA cannabis, cannabidiol and cannabinoid genotoxicity expressed in cancer incidence 2003–2017, parts 1–3” Open
View article: CJN volume 49 issue 4 Cover and Front matter
CJN volume 49 issue 4 Cover and Front matter Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
View article: Sex differences in the developing brain impact stress-induced epileptogenicity following hyperthermia-induced seizures
Sex differences in the developing brain impact stress-induced epileptogenicity following hyperthermia-induced seizures Open
Febrile seizures (FS) are common, affecting 2-5% of children between the ages of 3 months and 6 years. Complex FS occur in 10% of patients with FS and are strongly associated with mesial temporal lobe epilepsy. Current research suggests th…
View article: Improving the regulation of medical cannabis in Canada to better serve pediatric patients
Improving the regulation of medical cannabis in Canada to better serve pediatric patients Open
Key points Children with chronic debilitating illness and pain are increasingly using cannabis for medical purposes, particularly when conventional treatment options have limited benefit or substantial adverse effects. Caregivers are becom…
View article: Comparison of the real‐world effectiveness of vertical versus lateral functional hemispherotomy techniques for pediatric drug‐resistant epilepsy: A post hoc analysis of the HOPS study
Comparison of the real‐world effectiveness of vertical versus lateral functional hemispherotomy techniques for pediatric drug‐resistant epilepsy: A post hoc analysis of the HOPS study Open
Objective This study was undertaken to determine whether the vertical parasagittal approach or the lateral peri‐insular/peri‐Sylvian approach to hemispheric surgery is the superior technique in achieving long‐term seizure freedom. Methods …
View article: Potential Benefit of Add-on Δ9-Tetrahydrocannabinol in Pediatric Drug-Resistant Epilepsy: A Case Series
Potential Benefit of Add-on Δ9-Tetrahydrocannabinol in Pediatric Drug-Resistant Epilepsy: A Case Series Open
We present five cases of pediatric drug-resistant epilepsy (DRE) that failed management using high cannabidiol (CBD) doses, but had significant reduction in seizure frequency with reintroduction or increasing doses of tetrahydrocannabinol …
View article: Implementation of a Virtual Rapid Access Epilepsy Clinic
Implementation of a Virtual Rapid Access Epilepsy Clinic Open
An abstract is not available for this content. As you have access to this content, full HTML content is provided on this page. A PDF of this content is also available in through the ‘Save PDF’ action button.
View article: Hemispherectomy Outcome Prediction Scale: Development and validation of a seizure freedom prediction tool
Hemispherectomy Outcome Prediction Scale: Development and validation of a seizure freedom prediction tool Open
Objective To develop and validate a model to predict seizure freedom in children undergoing cerebral hemispheric surgery for the treatment of drug‐resistant epilepsy. Methods We analyzed 1267 hemispheric surgeries performed in pediatric pa…
View article: Hemispheric Surgery Outcome Prediction Scale: Development and Validation of a Seizure Freedom Prediction Tool
Hemispheric Surgery Outcome Prediction Scale: Development and Validation of a Seizure Freedom Prediction Tool Open