Evangelia Semizoglou
YOU?
Author Swipe
View article: A Reference Atlas of the Human Dorsal Root Ganglion
A Reference Atlas of the Human Dorsal Root Ganglion Open
Somatosensory perception largely emerges from diverse peripheral sensory neurons whose cell bodies reside in dorsal root ganglia (DRG). Damage or dysfunction of DRG neurons is a major cause of chronic pain and sensory loss. In mice, deep s…
View article: Protocol optimization improves the performance of multiplexed RNA imaging
Protocol optimization improves the performance of multiplexed RNA imaging Open
View article: Protocol Optimization Improves the Performance of Multiplexed RNA Imaging
Protocol Optimization Improves the Performance of Multiplexed RNA Imaging Open
Spatial transcriptomics has emerged as a powerful tool to define the cellular structure of diverse tissues. One such method is multiplexed error robust fluorescence in situ hybridization (MERFISH). MERFISH identifies RNAs with error tolera…
View article: <i>In vivo</i> calcium imaging reveals directional sensitivity of C‐low threshold mechanoreceptors
<i>In vivo</i> calcium imaging reveals directional sensitivity of C‐low threshold mechanoreceptors Open
C‐low threshold mechanoreceptors (C‐LTMRs) in animals (termed C‐tactile (CT) fibres in humans) are a subgroup of C‐fibre primary afferents, which innervate hairy skin and respond to low‐threshold punctate indentations and brush stimuli. Th…
View article: Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia
Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia Open
Sensory neurons in the dorsal root ganglion (DRG) and trigeminal ganglion (TG) are specialized to detect and transduce diverse environmental stimuli to the central nervous system. Single-cell RNA sequencing has provided insights into the d…
View article: Characterising the stimulus-response function of mouse C-Low threshold mechanoreceptors to mechanical stimuli<i>in vivo</i>
Characterising the stimulus-response function of mouse C-Low threshold mechanoreceptors to mechanical stimuli<i>in vivo</i> Open
C-low threshold mechanoreceptors (C-LTMRs) in animals (termed C-tactile (CT) fibres in humans) are a subgroup of C-fibre primary afferents, which innervate hairy skin and respond to low threshold punctate indentations and brush stimuli. Th…
View article: Serotonergic dysfunction impairs locomotor coordination in spinal muscular atrophy
Serotonergic dysfunction impairs locomotor coordination in spinal muscular atrophy Open
Neuromodulation by serotonin regulates the activity of neuronal networks responsible for a wide variety of essential behaviours. Serotonin (or 5-HT) typically activates metabotropic G protein-coupled receptors, which in turn initiate secon…
View article: Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia
Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia Open
Peripheral sensory neurons in the dorsal root ganglion (DRG) and trigeminal ganglion (TG) are specialized to detect and transduce diverse environmental stimuli including touch, temperature, and pain to the central nervous system. Recent ad…
View article: TRPA1 analgesia is mediated by kappa opioid receptors
TRPA1 analgesia is mediated by kappa opioid receptors Open
TRPA1 expressed in peripheral sensory neurons is important for nociception. Pharmacological inhibition or genetic ablation of TRPA1 profoundly reduces normal behavioural sensitivity to noxious cold and mechanical stimulation, as well as se…
View article: Sodium-calcium exchanger-3 regulates pain “wind-up”: From human psychophysics to spinal mechanisms
Sodium-calcium exchanger-3 regulates pain “wind-up”: From human psychophysics to spinal mechanisms Open