Ewa Kisiel-Nawrot
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View article: Towards Anticancer and Antibacterial Agents: Design and Synthesis of 1,2,3-Triazol-quinobenzothiazine Derivatives
Towards Anticancer and Antibacterial Agents: Design and Synthesis of 1,2,3-Triazol-quinobenzothiazine Derivatives Open
In this paper, we describe a new method for synthesizing hybrid combinations of 1,2,3-triazoles with a tetracyclic quinobenzothiazinium system. The developed approach allowed for the production of a series of new azaphenothiazine derivativ…
View article: Anticancer Efficacy of Antibacterial Quinobenzothiazines
Anticancer Efficacy of Antibacterial Quinobenzothiazines Open
The antitumor potency of a series of designed and prepared antibacterial quinobenzothiazines was evaluated against different types of human cancer cell lines, such as glioblastoma SNB-19, lung adenocarcinoma A549 and breast cancer T47D, an…
View article: Design, Synthesis and Antimicrobial Properties of New Tetracyclic Quinobenzothiazine Derivatives
Design, Synthesis and Antimicrobial Properties of New Tetracyclic Quinobenzothiazine Derivatives Open
A new method for modifying the structure of tetracyclic quinobenzothiazinium derivatives has been developed, allowing introduction of various substituents at different positions of the benzene ring. The method consists of reacting appropri…
View article: Lack of berberine effect on bone mechanical properties in rats with experimentally induced diabetes
Lack of berberine effect on bone mechanical properties in rats with experimentally induced diabetes Open
Multidirectional health-promoting activities of some plant-derived substances make them candidates for drugs used in diabetes and its complications such as osteoporosis. Berberine is a compound for which both antidiabetic and antiosteoporo…
View article: Effects of diosgenin on the skeletal system in rats with experimental type 1 diabetes
Effects of diosgenin on the skeletal system in rats with experimental type 1 diabetes Open
There is a great interest in substances of plant origin, which may exert health-promoting activities in diabetes and its complications. Previous studies suggested that diosgenin may favorably affect both glucose metabolism and osteoporosis…