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View article: Beetroot Juice Supplementation as a Healthy Aging Strategy Through Improving Physical Performance and Cognitive Functions: A Systematic Review
Beetroot Juice Supplementation as a Healthy Aging Strategy Through Improving Physical Performance and Cognitive Functions: A Systematic Review Open
Background: Findings show that beetroot-derived nitrates can improve endurance, oxygen efficiency, muscular power, recovery and cardiovascular function, particularly in recreationally active or moderately trained individuals. However, resu…
View article: Establishment of Shoot Cultures of Nepeta curviflora Boiss., Scale-Up in a Nutrient Sprinkle Bioreactor and Phytochemical Analysis
Establishment of Shoot Cultures of Nepeta curviflora Boiss., Scale-Up in a Nutrient Sprinkle Bioreactor and Phytochemical Analysis Open
Shoot cultures of Nepeta curviflora were used to test the effect of 6-benzylaminopurine (BAP) and riboside 6-benzylaminopurine (r-BAP) on the growth and production of phenolic compounds. The best multiplication was achieved on agar Murashi…
View article: Effect of Ginseng Supplementation on Exercise Endurance as a Support for Cardiovascular Disease Management: A Systematic Review and Meta-Analysis
Effect of Ginseng Supplementation on Exercise Endurance as a Support for Cardiovascular Disease Management: A Systematic Review and Meta-Analysis Open
Ginseng has multi-directional pharmacological properties. Some data suggest that ginseng can enhance physical endurance, which, in turn, leads to protection of the cardiovascular system. However, not all experiments are conclusive. For thi…
View article: Carvacrol as a Stimulant of the Expression of Key Genes of the Ginsenoside Biosynthesis Pathway and Its Effect on the Production of Ginseng Saponins in Panax quinquefolium Hairy Root Cultures
Carvacrol as a Stimulant of the Expression of Key Genes of the Ginsenoside Biosynthesis Pathway and Its Effect on the Production of Ginseng Saponins in Panax quinquefolium Hairy Root Cultures Open
The accumulation of ginsenosides (triterpenic saponins) was determined in Panax quinquefolium hairy root cultures subjected to an elicitation process using carvacrol at 5, 10, 25, 50, 100, 250, and 500 μM concentrations during 24 and 72 h …
View article: Antioxidant and Anti-inflammatory Effects of α-Lipoic Acid on Lipopolysaccharide-induced Oxidative Stress in Rat Kidney
Antioxidant and Anti-inflammatory Effects of α-Lipoic Acid on Lipopolysaccharide-induced Oxidative Stress in Rat Kidney Open
α-Lipoic acid (α-LA) is a naturally occurring organosulfur component. Oxidative stress plays an essential role in the pathogenesis of various diseases, such as kidney and cardiovascular diseases, diabetes, neurodegenerative disorders, canc…
View article: Upscaling biomass production of rosmarinic acid-rich hairy root cultures of Agastache rugosa
Upscaling biomass production of rosmarinic acid-rich hairy root cultures of Agastache rugosa Open
Agastache rugosa (Fisch. & C.A.Mey.) Kuntze known as Korean Mint is a medicinal and aromatic plant containing rosmarinic acid as a major bioactive polyphenol but its content in this herbal drug is variable. Plant in vitro culture is one of…
View article: Linalool as a novel natural factor enhancing ginsenoside production in hairy root cultures of American ginseng
Linalool as a novel natural factor enhancing ginsenoside production in hairy root cultures of American ginseng Open
Ginsenosides are triterpenoid saponins, accumulated in root of Panax qiunquefolius . These secondary metabolites have numerous pharmacological properties such as: antimicrobial, antioxidant, anti-inflammation, anticancer. They have been fo…
View article: Improved efficacy of eugenol and <i>trans</i>-anethole in combination with octenidine dihydrochloride against <i>Candida albicans</i> and <i>Candida parapsilosis</i>
Improved efficacy of eugenol and <i>trans</i>-anethole in combination with octenidine dihydrochloride against <i>Candida albicans</i> and <i>Candida parapsilosis</i> Open
Candidiasis is a fungal infection caused by yeasts from the Ogenus Candida. Considering increasing antifungal resistance rates the activity was analyzed of natural compounds to eradicate Candida spp. The aim of the study was to check the a…
View article: Linalool as a novel natural factor enhancing ginsenoside production in hairy root cultures of American ginseng
Linalool as a novel natural factor enhancing ginsenoside production in hairy root cultures of American ginseng Open
Ginsenosides are triterpenoid saponins that are accumulated in root of Panax qiunquefolius . These secondary metabolites have numerous pharmacological properties such as: antimicrobial, antioxidant, anti-inflammation, anticancer. They have…
View article: The Effect of Herbal Supplements on Blood Pressure: Systematic Review and Meta-Analysis
The Effect of Herbal Supplements on Blood Pressure: Systematic Review and Meta-Analysis Open
Herbal supplements rich in phenolic compounds are evidenced to have a protective effect against cardiovascular diseases. Therefore, they are suggested to be included in diets for people with hypertension (HT). HT is a global health problem…
View article: Elicitation of solid callus cultures of Salvia miltiorrhiza Bunge with salicylic acid and a synthetic auxin (1-naphthaleneacetic acid)
Elicitation of solid callus cultures of Salvia miltiorrhiza Bunge with salicylic acid and a synthetic auxin (1-naphthaleneacetic acid) Open
The presented study analyses the influence of salicylic acid (SA) and the synthetic auxin 1-naphthaleneacetic acid (NAA) on total tanshinone level and on dihydrotanshinone (DHT), cryptotanshinone (CT), tanshinine I (TI) and tanshinone IIA …
View article: Physical activity of future health care professionals: adherence to current recommendations
Physical activity of future health care professionals: adherence to current recommendations Open
This study revealed a low level of leisure time PA among the students, and no habit of regular PA. Some changes in medical education should be suggested to include physical education as a long-term subject in medical school curricula. Futu…
View article: Panax quinquefolium L. Ginsenosides from Hairy Root Cultures and Their Clones Exert Cytotoxic, Genotoxic and Pro-Apoptotic Activity towards Human Colon Adenocarcinoma Cell Line Caco-2
Panax quinquefolium L. Ginsenosides from Hairy Root Cultures and Their Clones Exert Cytotoxic, Genotoxic and Pro-Apoptotic Activity towards Human Colon Adenocarcinoma Cell Line Caco-2 Open
American ginseng, Panax quinquefolium (L.), is traditionally used in folk medicine. It exhibits a range of anti-inflammatory, hepatoprotective, anti-diabetic, anti-obesity, anti-hyperlipidemic and anti-carcinogenic effects. Its main compon…
View article: The time spent sitting does not always mean a low level of physical activity.
The time spent sitting does not always mean a low level of physical activity. Open
Background: The problem of spending most of the day in a sitting position concerns all people, regardless of their age. Unfortunately, this trend is more and more often observed among young people. The aim of the study was to assess self-r…
View article: Ginsenoside and phenolic compounds in hydromethanolic extracts of American ginseng cell cultures and their antioxidant properties
Ginsenoside and phenolic compounds in hydromethanolic extracts of American ginseng cell cultures and their antioxidant properties Open
The present study was performed to investigate the antioxidant properties of callus and suspension culture extracts of Panax quinquefolium (American ginseng). The ginsenoside content and the total phenolic content (TPC) in these cultures w…
View article: Panax quinquefolium hairy root extracts and their effect in connections with antibiotics against pathogenic bacteria – preliminary study
Panax quinquefolium hairy root extracts and their effect in connections with antibiotics against pathogenic bacteria – preliminary study Open
The aim of the present study was to determine the level of ginsenosides in extracts from hairy root A, B, G clones of Panax quinquefolium and their action with antibiotics against clinical bacterial isolates. The content of ginsenosides (…
View article: The content of triterpene saponins and phenolic compounds in American ginseng hairy root extracts and their antioxidant and cytotoxic properties
The content of triterpene saponins and phenolic compounds in American ginseng hairy root extracts and their antioxidant and cytotoxic properties Open
Panax quinquefolium is a perennial herb of the Araliaceae family native to North America. Its roots have been used in traditional and Chinese medicine. The aim of this study was to determine the phenolic profile of methanolic extracts of P…
View article: American Ginseng (Panax quinquefolium L.) as a Source of Bioactive Phytochemicals with Pro-Health Properties
American Ginseng (Panax quinquefolium L.) as a Source of Bioactive Phytochemicals with Pro-Health Properties Open
Panax quinquefolium L. (American Ginseng, AG) is an herb characteristic for regions of North America and Asia. Due to its beneficial properties it has been extensively investigated for decades. Nowadays, it is one of the most commonly appl…
View article: Synergistic effect of fennel essential oil and hydrogenperoxide on bacterial biofilm
Synergistic effect of fennel essential oil and hydrogenperoxide on bacterial biofilm Open
Combination of fennel essential oil containing nearly 80% trans-anethole and H2O2 represents a potential for further basic and applied research on wound management.
View article: Abscisic Acid Regulates the 3-Hydroxy-3-methylglutaryl CoA Reductase Gene Promoter and Ginsenoside Production in Panax quinquefolium Hairy Root Cultures
Abscisic Acid Regulates the 3-Hydroxy-3-methylglutaryl CoA Reductase Gene Promoter and Ginsenoside Production in Panax quinquefolium Hairy Root Cultures Open
Panax quinquefolium hairy root cultures synthesize triterpenoid saponins named ginsenosides, that have multidirectional pharmacological activity. The first rate-limiting enzyme in the process of their biosynthesis is 3-hydroxy-3-methylglut…
View article: The Increase of Triterpene Saponin Production Induced by Trans-Anethole in Hairy Root Cultures of Panax quinquefolium
The Increase of Triterpene Saponin Production Induced by Trans-Anethole in Hairy Root Cultures of Panax quinquefolium Open
In vitro cultivation is an effective way to increase pharmaceutical production. To increase ginsenoside production in hairy root cultures of American ginseng, the present study uses trans-anethole as an elicitor. The content of nine triter…
View article: Ginsenoside content in suspension cultures of Panax quinquefolium L. cultivated in shake flasksand stirred-tank bioreactor
Ginsenoside content in suspension cultures of Panax quinquefolium L. cultivated in shake flasksand stirred-tank bioreactor Open
Plant suspension cultures are described as a source for the acquisition of medicinal secondary metabolites which in the future may become an alternative to traditional raw materials. This study demonstrates that the cell cultures of one of…
View article: Influence of methyl jasmonate on ginsenoside biosynthesis in suspension cultures of Panax quinquefolium L.
Influence of methyl jasmonate on ginsenoside biosynthesis in suspension cultures of Panax quinquefolium L. Open
Panax quinquefolium L., belonging to the Araliaceae family, along with P. ginseng is one of the well-known species of ginseng. Multidirectional pharmacological action of this plant is attributed to triterpene saponins called ginsenosides. …
View article: Antibiotic resistance among Escherichia coli urinary isolates and their susceptibility to clove essential oil
Antibiotic resistance among Escherichia coli urinary isolates and their susceptibility to clove essential oil Open
Escherichia coli is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium, which is a primary cause of urinary tract infections. Resistance to antibiotics has become a particular problem in recent decades. Consequently, …
View article: Yeast Extract Stimulates Ginsenoside Production in Hairy Root Cultures of American Ginseng Cultivated in Shake Flasks and Nutrient Sprinkle Bioreactors
Yeast Extract Stimulates Ginsenoside Production in Hairy Root Cultures of American Ginseng Cultivated in Shake Flasks and Nutrient Sprinkle Bioreactors Open
One of the most effective strategies to enhance metabolite biosynthesis and accumulation in biotechnological systems is the use of elicitation processes. This study assesses the influence of different concentrations of yeast extract (YE) o…