Ewa Migacz
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View article: S100a8 and s100a9 are elevated in aortic wall from patients with moderate-and-severe obstructive sleep apnea syndrome
S100a8 and s100a9 are elevated in aortic wall from patients with moderate-and-severe obstructive sleep apnea syndrome Open
This study provides novel evidence that S100A8 and S100A9 are overexpressed in the aortic walls of patients with moderate-to-severe OSA. These findings suggest a potential role for these proteins in OSA-related vascular inflammation and at…
View article: Elevation of CD40/CD40L Inflammatory Pathway Molecules in Carotid Plaques from Moderate-and-Severe Obstructive Sleep Apnea Patients
Elevation of CD40/CD40L Inflammatory Pathway Molecules in Carotid Plaques from Moderate-and-Severe Obstructive Sleep Apnea Patients Open
A chronic inflammatory process characteristic of obstructive sleep apnea promotes vascular endothelial dysfunction and atherogenesis. This process can lead to destabilization and rupture of cardiovascular plaques, which clinically manifest…
View article: The effect of in-lab polysomnography and home sleep polygraphy on sleep position
The effect of in-lab polysomnography and home sleep polygraphy on sleep position Open
Purpose Little is known regarding the influence of in-laboratory polysomnography (PSG) equipment on sleep position, especially on the prevalence of supine positioning, which in many cases may lead to a more severe sleep apnea diagnosis. Th…
View article: TLRs and RAGE are elevated in carotid plaques from patients with moderate-to-severe obstructive sleep apnea syndrome
TLRs and RAGE are elevated in carotid plaques from patients with moderate-to-severe obstructive sleep apnea syndrome Open
Background There is growing evidence that obstructive sleep apnea (OSA) promotes vascular endothelial dysfunction and atherogenesis. Pathways that mediate this pathology may include Toll-like receptors (TLRs) and receptor for advanced glyc…
View article: ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy
ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy Open
The nine identified human homologues of E . coli AlkB 2-oxoglutarate (2OG) and Fe(II)-dependent dioxygenase, ALKBH1-8 and FTO, display different substrate specificities and diverse biological functions. Here we discovered the combined over…
View article: RAGE and TLRs as Key Targets for Antiatherosclerotic Therapy
RAGE and TLRs as Key Targets for Antiatherosclerotic Therapy Open
Receptor for advanced glycation end-products (RAGE) and toll-like receptors (TLRs) are the key factors indicating a danger to the organism. They recognize the microbial origin pathogen-associated molecular patterns (PAMPs) or damage-associ…
View article: Successful treatment of postoperative, radiation-associated wound dehiscence around tracheostomy with negative pressure wound therapy.
Successful treatment of postoperative, radiation-associated wound dehiscence around tracheostomy with negative pressure wound therapy. Open
We present case report of 62-year-old man who underwent total laryngectomy, bilateral neck dissection and radiotherapy due to laryngeal cancer. After 11 months he was reoperated because of a local recurrence. The second procedure was compl…
View article: 1054 SLEEP DISORDERED BREATHING IN PATIENTS SCHEDULED FOR CAROTID ENDARTERECTOMY
1054 SLEEP DISORDERED BREATHING IN PATIENTS SCHEDULED FOR CAROTID ENDARTERECTOMY Open
Obstructive sleep apnea (OSA) seems to be an independent risk factor for carotid atherosclerosis, but there are limited data on the coexistence of OSA and hemodynamically significant carotid stenosis.The aim of this study was to determine …