Eyla C. Arteaga
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View article: Uremic serum exposure leads to differential phenotypic switch in porcine arterial and venous smooth muscle cells
Uremic serum exposure leads to differential phenotypic switch in porcine arterial and venous smooth muscle cells Open
This study was the first one to directly explore the differential response of arterial VSMCs and venous VSMCs to uremic serum exposure side by side. Both similarities and differences were detected in this in vitro study, which provides ins…
View article: Post-translational modification of H2B C-terminal helix regulates nucleosome interactions and chromatin signaling
Post-translational modification of H2B C-terminal helix regulates nucleosome interactions and chromatin signaling Open
Histone H2B contains a highly conserved C-terminal (H2B αC) helix that has been implicated in chromatin interactions and dynamics. The H2B αC helix comprising residues 105–125 is positioned adjacent to a major site of nucleosome interactio…
View article: Characterization of Protein Expression and Signaling Pathway Activation That May Contribute to Differential Biological Functions in Porcine Arterial and Venous Smooth Muscle Cells
Characterization of Protein Expression and Signaling Pathway Activation That May Contribute to Differential Biological Functions in Porcine Arterial and Venous Smooth Muscle Cells Open
Arteriovenous fistulae (AVF) are the preferred mode of dialysis vascular access but have a maturation failure rate of over 50%. Venous segment stenosis is one of the main reasons. However, the reasons for the prevalence of stenosis in the …
View article: APC/C-mediated ubiquitylation of extranucleosomal histone complexes lacking canonical degrons
APC/C-mediated ubiquitylation of extranucleosomal histone complexes lacking canonical degrons Open
View article: WCN25-4450 UREMIA, ANGIOPLASTY INJURY AND VESSEL TYPE (ARTERY VS VEIN) ACTIVATE DIFFERENTIAL GENE EXPRESSION AND PATHWAY PROFILES: ? ROLE IN VASCULAR DISEASE AND VASCULAR ACCESS DYSFUNCTION IN ESKD
WCN25-4450 UREMIA, ANGIOPLASTY INJURY AND VESSEL TYPE (ARTERY VS VEIN) ACTIVATE DIFFERENTIAL GENE EXPRESSION AND PATHWAY PROFILES: ? ROLE IN VASCULAR DISEASE AND VASCULAR ACCESS DYSFUNCTION IN ESKD Open
View article: WCN25-3906 DIFFERENTIAL GENE EXPRESSION AND SIGNAL PATHWAY ACTIVATION LEAD TO DIFFERENCES IN CELL PROLIFERATION AND MIGRATION OF VENOUS AND ARTERIAL PIG SMOOTH MUSCLE CELLS (SMC)
WCN25-3906 DIFFERENTIAL GENE EXPRESSION AND SIGNAL PATHWAY ACTIVATION LEAD TO DIFFERENCES IN CELL PROLIFERATION AND MIGRATION OF VENOUS AND ARTERIAL PIG SMOOTH MUSCLE CELLS (SMC) Open
View article: WCN25-3999 UREMIC SERUM RESULTS IN AN ACTIVATION OF PIG VENOUS AND ARTERIAL SMC: IS THIS RESPONSIBLE FOR VASCULAR ACCESS DYSFUNCTION AND AGGRESSIVE VASCULAR DISEASE IN ESKD?
WCN25-3999 UREMIC SERUM RESULTS IN AN ACTIVATION OF PIG VENOUS AND ARTERIAL SMC: IS THIS RESPONSIBLE FOR VASCULAR ACCESS DYSFUNCTION AND AGGRESSIVE VASCULAR DISEASE IN ESKD? Open
View article: Structural basis of paralog-specific KDM2A/B nucleosome recognition
Structural basis of paralog-specific KDM2A/B nucleosome recognition Open
View article: Structural basis of paralog-specific KDM2A/B nucleosome recognition
Structural basis of paralog-specific KDM2A/B nucleosome recognition Open
View article: Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity
Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity Open
A key role of chromatin kinases is to phosphorylate histone tails during mitosis to spatiotemporally regulate cell division. Vaccinia-related kinase 1 (VRK1) is a serine–threonine kinase that phosphorylates histone H3 threonine 3 (H3T3) al…
View article: A Validated Functional Analysis of Partner and Localizer of BRCA2 Missense Variants for Use in Clinical Variant Interpretation
A Validated Functional Analysis of Partner and Localizer of BRCA2 Missense Variants for Use in Clinical Variant Interpretation Open
View article: A Validated Functional Analysis of PALB2 Missense Variants for Use in Clinical Variant Interpretation
A Validated Functional Analysis of PALB2 Missense Variants for Use in Clinical Variant Interpretation Open
Clinical genetic testing readily detects germline genetic variants. Yet, the evidence available for variant classification as benign or pathogenic is often limited by the rarity of individual variants, leading to many “variant of uncertain…