Explanipedia

Alterations in the Growth Hormone/Insulin-Like Growth Factor I Pathways in Feline GM1 Gangliosidosis1 Open

Nancy R. Cox, Nancy E. Morrison, J. L. Sartin, F. C. Buonomo, Barbara Steele , et al. · 1999

Cats affected with feline GM1 gangliosidosis, an autosomal, recessively inherited, lysosomal enzymopathy, have progressive neurological dysfunction, premature thymic involution, stunted growth, and premature death. Although increased membr…

Radiographic, Densitometric, and Biomechanical Effects of Recombinant Canine Somatotropin in an Unstable Ostectomy Gap Model of Bone Healing in Dogs Open

Darryl L. Millis, BRENT E. WTLKENS, Gregory B. Daniel, Karl F. Hübner, Archie Mathews , et al. · 1998

Objective —To determine the effect of recombinant canine somatotropin (STH) on radiographic, densitometric, and biomechanical aspects of bone healing using an unstable ostectomy gap model. Study Design —After an ostectomy of the midshaft r…

Metabolic and histologic effects of recombinant canine somatotropin on bone healing in dogs, using an unstable ostectomy gap model Open

Brent E. Wilkens, Darryl L. Millis, Gregory B. Daniel, Linda Munson, Kanaiyala R. Patel , et al. · 1996

Objective To investigate the effect of recombinant canine somatotropin (STH) on the metabolic and histologic aspects of bone healing in dogs, using an unstable os-tectomy gap model. Animals 8 mature dogs. Procedure A 3-mm ostectomy of the …

Endocrine and metabolite responses to porcine growth hormone administered by sustained release implant for different lengths of time in male pigs. Open

J. Klindt, F. C. Buonomo, T. Wise, J. T. Yen · 1996

The effects of long term administration of GH on serum concentrations of hormones and metabolites was investigated in intact and castrate male swine. At 10 weeks of age, male swine were assigned to six treatments (n = 10/group): nonimplant…

Obesity and dehydroepiandrosterone/dehydroepiandrosterone sulfate relationships in lean, obese, and meat-type cross-bred boars: responses to porcine growth hormone. Open

T. Wise, J. Klindt, F. C. Buonomo · 1995

As so many variables can affect obesity (age, genetics, health status), new directions, other than reducing or altering diet, are being pursued in controlling obesity in our society. Both dehydroepiandrosterone (DHEA) and GH have reported …

Physiologic and therapeutic roles of somatotropin effects in adult animals Open

Clifton A. Baile, F. C. Buonomo, R.J. Collier, C. L. McLaughlin · 1994

Fertility of Transgenic Female Mice Expressing Bovine Growth Hormone or Human Growth Hormone Variant Genes1 Open

Erick M. Naar, Andrzej Bartke, Subeer S. Majumdar, F. C. Buonomo, Jeung S. Yun , et al. · 1991

Although growth hormone (GH) exerts various direct and indirect stimulatory effects on gonadal development and function, excessive levels of GH in acromegalic patients and in transgenic animals are often associated with reproductive disord…

Periparturient Changes in Secretion and Mammary Uptake of Insulin and in Concentrations of Insulin and Insulin-Like Growth Factors in Milk of Dairy Cows Open

P.V. Malven, H.H. Head, R.J. Collier, F. C. Buonomo · 1987

Mammary uptake of insulin from blood was quantified near parturition in nine dairy cows, some of which were milked prepartum to induce prepartum lactogenesis. Milk samples were immunoassayed for concentrations of insulin, insulin-like grow…

Growth Hormone-Releasing Factor Effects on Pituitary Function, Growth, and Lactation Open

Clifton A. Baile, F. C. Buonomo · 1987

Growth and lactation are complex processes controlled by several metabolic hormones such as insulin, glucagon, and thyroid hormones but most notably growth hormone. Growth hormone secretion is regulated by two hypothalamic hormones, somato…

Effects of Gradation in Protein-Calorie Restriction on the Hypothalo-Pituitary-Gonadal Axis in Young Domestic Fowl Open

F. C. Buonomo, Paul Griminger, Colin G. Scanes · 1982

The effect of protein-calorie restriction on the circulating concentration of luteinizing hormone (LH) was investigated in the young domestic fowl. Two-week-old broiler chicks were fed isocaloric synthetic diets with varying levels of soy …

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