Francesco P. Cappuccio
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View article: World Hypertension League perspective on public health initiatives to reduce global sodium consumption: are we not seeing the elephant in the room?
World Hypertension League perspective on public health initiatives to reduce global sodium consumption: are we not seeing the elephant in the room? Open
Sodium reduction is a well-established strategy for the prevention of cardiovascular disease (CVD), yet effective implementation requires context-specific approaches. Low-sodium salt substitutes (LSSS), in which sodium chloride is partiall…
View article: Salt substitutes and misrepresentation of WHO recommendations
Salt substitutes and misrepresentation of WHO recommendations Open
View article: Nocturnal blood pressure: pathophysiology, measurement and clinical implications. Position paper of the European Society of Hypertension
Nocturnal blood pressure: pathophysiology, measurement and clinical implications. Position paper of the European Society of Hypertension Open
Interest in the pathophysiology, measurement, and clinical implications of nocturnal blood pressure (BP) has significantly increased due to its strong association with cardiovascular risk, and its importance was recognized by the 2023 Euro…
View article: Dietary risk factors for non-communicable diseases among Omani adults by latent class analysis and structural equation modelling
Dietary risk factors for non-communicable diseases among Omani adults by latent class analysis and structural equation modelling Open
Background Risk factor surveillance is vital for public health interventions in non-communicable diseases (NCD) control due to a noticeable nutrition transition among the population affecting dietary patterns. The objective was to investig…
View article: FOUND Trial: randomised controlled trial study protocol for case finding of obstructive sleep apnoea in primary care using a novel device
FOUND Trial: randomised controlled trial study protocol for case finding of obstructive sleep apnoea in primary care using a novel device Open
Introduction Obstructive sleep apnoea (OSA) is a common, but underdiagnosed, sleep disorder. If untreated, it leads to poor health outcomes, including Alzheimer’s disease, cancer, cardiovascular disease and all-cause mortality. Our aim is …
View article: Effect of timed dosing of usual antihypertensives according to patient chronotype on cardiovascular outcomes: the Chronotype sub-study cohort of the Treatment in Morning versus Evening (TIME) study
Effect of timed dosing of usual antihypertensives according to patient chronotype on cardiovascular outcomes: the Chronotype sub-study cohort of the Treatment in Morning versus Evening (TIME) study Open
The TIME study was funded by the British Heart Foundation (CS/14/1/30659) with support from the British and Irish Hypertension Society.
View article: Common Nutritional Shortcomings in Vegetarians and Vegans
Common Nutritional Shortcomings in Vegetarians and Vegans Open
The popularity of vegetarian and vegan diets is growing due to increased awareness of the environmental and health benefits of such diets. However, despite the consumption of meatless diets being associated with decreased risk of chronic d…
View article: Pertinence of Salt-Related Knowledge and Reported Behaviour on Salt Intake in Adults: A Cross-Sectional Study
Pertinence of Salt-Related Knowledge and Reported Behaviour on Salt Intake in Adults: A Cross-Sectional Study Open
The association between salt-related knowledge, attitude, behaviour (KAB) and actual salt consumption in Greek adults is uncertain. This study investigates the correlation between salt intake, gauged by 24-h urinary sodium excretion, with …
View article: Comment on: Less sodium and more potassium to reduce cardiovascular risk and the PURE study
Comment on: Less sodium and more potassium to reduce cardiovascular risk and the PURE study Open
View article: Perspectives on improving blood pressure control to reduce the clinical and economic burden of hypertension
Perspectives on improving blood pressure control to reduce the clinical and economic burden of hypertension Open
The clinical and economic burden of hypertension is high and continues to increase globally. Uncontrolled hypertension has severe but avoidable long‐term consequences, including cardiovascular diseases, which are among the most burdensome …
View article: Rising arterial stiffness with accumulating comorbidities associates with heart failure with preserved ejection fraction
Rising arterial stiffness with accumulating comorbidities associates with heart failure with preserved ejection fraction Open
Aims Comorbidities play a significant role towards the pathophysiology of heart failure with preserved ejection fraction (HFpEF), characterized by abnormal macrovascular function and altered ventricular–vascular coupling. However, our unde…
View article: Exploring educational inequalities in hypertension control, salt knowledge and awareness, and patient advice: insights from the WHO STEPS surveys of adults from nine Eastern European and Central Asian countries
Exploring educational inequalities in hypertension control, salt knowledge and awareness, and patient advice: insights from the WHO STEPS surveys of adults from nine Eastern European and Central Asian countries Open
Objective: To inform strategies aimed at improving blood pressure (BP) control and reducing salt intake, we assessed educational inequalities in high blood pressure (HBP) awareness, treatment and control; physician’s advice on salt reducti…
View article: Effect of Potassium Supplementation on Endothelial Function: A Systematic Review and Meta-Analysis of Intervention Studies
Effect of Potassium Supplementation on Endothelial Function: A Systematic Review and Meta-Analysis of Intervention Studies Open
(1) Background: Endothelial dysfunction is an early predictor of cardiovascular diseases. Although a large body of evidence shows an inverse association between potassium intake and cardiovascular risk, the studies on endothelial function …
View article: Clinicians’ and Patients’ Perceptions and Use of the Word “Cured” in Cancer Care: An Italian Survey
Clinicians’ and Patients’ Perceptions and Use of the Word “Cured” in Cancer Care: An Italian Survey Open
Background. The words “hope” and “cure” were used in a greater number of articles and sentences in narrative and editorial papers than in primary research. Despite concomitant improvements in cancer outcomes, the related reluctance to use …
View article: Comment on Hogas et al. Salt, Not Always a Cardiovascular Enemy? A Mini-Review and Modern Perspective. Medicina 2022, 58, 1175
Comment on Hogas et al. Salt, Not Always a Cardiovascular Enemy? A Mini-Review and Modern Perspective. Medicina 2022, 58, 1175 Open
Hogas et al. recently published their perspective on dietary salt in a mini review [...]
View article: Dietary Potassium Intake and Risk of Diabetes: A Systematic Review and Meta-Analysis of Prospective Studies
Dietary Potassium Intake and Risk of Diabetes: A Systematic Review and Meta-Analysis of Prospective Studies Open
(1) Background: Dietary potassium intake is positively associated with reduction of cardiovascular risk. Several data are available on the relationship between dietary potassium intake, diabetes risk and glucose metabolism, but with incons…
View article: Population-level salt intake in the WHO European Region in 2022: a systematic review
Population-level salt intake in the WHO European Region in 2022: a systematic review Open
Objective: The WHO recommends that adults consume less than 5 g of salt per day to reduce the risk of CVD. This study aims to examine the average population daily salt intake in the fifty-three Member States of the WHO European Region. Des…
View article: Sodium, Potassium and Iodine Intake in an Adult Population of Lithuania
Sodium, Potassium and Iodine Intake in an Adult Population of Lithuania Open
Hypertension is a leading risk factor for cardiovascular events and death. A reduction in salt intake is among the most cost-effective strategies to reduce blood pressure and the risk of cardiovascular diseases. Increasing potassium lowers…
View article: Dietary sodium and cardiovascular disease in China: addressing the authors’ response, statements and claims
Dietary sodium and cardiovascular disease in China: addressing the authors’ response, statements and claims Open
Campbell, Norman R.C.; He, Feng J.; McLean, Rachael M.; Cappuccio, Francesco P.; Woodward, Mark; MacGregor, Graham A.; Guichon, Juliet; Mitchell, Ian Author Information
View article: 2022 World Hypertension League, Resolve To Save Lives and International Society of Hypertension dietary sodium (salt) global call to action
2022 World Hypertension League, Resolve To Save Lives and International Society of Hypertension dietary sodium (salt) global call to action Open
This fact sheet and global call to action is aimed at nutrition, hypertension, cardiovascular and other health care clinicians and scientists, and health advocates, as well as the organizations to which they belong. The ‘call’ is to align …
View article: Plant-Based Dietary Patterns for Human and Planetary Health
Plant-Based Dietary Patterns for Human and Planetary Health Open
The coronavirus pandemic has acted as a reset on global economies, providing us with the opportunity to build back greener and ensure global warming does not surpass 1.5 °C. It is time for developed nations to commit to red meat reduction …
View article: Use of technology to prevent, detect, manage and control hypertension in sub-Saharan Africa: a systematic review
Use of technology to prevent, detect, manage and control hypertension in sub-Saharan Africa: a systematic review Open
Objective To identify and assess the use of technologies, including mobile health technology, internet of things (IoT) devices and artificial intelligence (AI) in hypertension healthcare in sub-Saharan Africa (SSA). Design Systematic revie…
View article: Reply to Hu et al. Significant association of obstructive sleep apnoea with increased risk for fatal COVID-19
Reply to Hu et al. Significant association of obstructive sleep apnoea with increased risk for fatal COVID-19 Open
View article: Dissecting the Polygenic Basis of Primary Hypertension: Identification of Key Pathway-Specific Components
Dissecting the Polygenic Basis of Primary Hypertension: Identification of Key Pathway-Specific Components Open
Introduction and Objectives Genome-wide association studies have identified a high number of genetic loci associated with hypertension suggesting the presence of an underlying polygenic architecture. In this study, we aimed to dissect the …
View article: Sodium and Health: Old Myths and a Controversy Based on Denial
Sodium and Health: Old Myths and a Controversy Based on Denial Open
Purpose of Review The scientific consensus on which global health organizations base public health policies is that high sodium intake increases blood pressure (BP) in a linear fashion contributing to cardiovascular disease (CVD). A modera…
View article: The use of artificial intelligence systems in diagnosis of pneumonia via signs and symptoms: A systematic review
The use of artificial intelligence systems in diagnosis of pneumonia via signs and symptoms: A systematic review Open
View article: Heart failure with preserved ejection fraction (HFpEF) pathophysiology study (IDENTIFY-HF): rise in arterial stiffness associates with HFpEF with increase in comorbidities
Heart failure with preserved ejection fraction (HFpEF) pathophysiology study (IDENTIFY-HF): rise in arterial stiffness associates with HFpEF with increase in comorbidities Open
Background There has been a shift in paradigm proposing that comorbidities play a significant role towards the pathophysiology of the heart failure with preserved ejection fraction (HFpEF) syndrome. Further, HFpEF patients have abnormal ma…
View article: Levels of dietary sodium intake: diverging associations with arterial stiffness and Atheromatosis. Concerns about the evidence review and methods
Levels of dietary sodium intake: diverging associations with arterial stiffness and Atheromatosis. Concerns about the evidence review and methods Open
View article: Dietary Sodium 'Controversy'—Issues and Potential Solutions
Dietary Sodium 'Controversy'—Issues and Potential Solutions Open
Inappropriate research methodology, lack of rigor in research, conflicts of interest and commercial bias, questions of professional conduct, and lack of policies to protect public interests are likely to contribute to the controversy about…
View article: PRESERVE: Randomized Trial of Intensive Versus Standard Blood Pressure Control in Small Vessel Disease
PRESERVE: Randomized Trial of Intensive Versus Standard Blood Pressure Control in Small Vessel Disease Open
Background and Purpose: In cerebral small vessel disease, cerebral blood flow and autoregulation are impaired and therefore excessive blood pressure reduction could possibly accelerate white matter damage and worsen outcome. The trial dete…