Luca Cozzi
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View article: Bilateral breast treatment in a single arc using RapidArc Dynamic: A planning comparison with conventional volumetric modulated arc therapy
Bilateral breast treatment in a single arc using RapidArc Dynamic: A planning comparison with conventional volumetric modulated arc therapy Open
Purpose Synchronous bilateral breast cancer (SBBC) presents significant radiotherapy planning challenges due to complex target volumes near critical organs. This study evaluated RapidArc Dynamic (RAD), a novel technique integrating dynamic…
View article: Effective spot size parameters for Acuros dose calculation algorithm using enhanced leaf modelling: Estimation based on small rectangular MLC fields
Effective spot size parameters for Acuros dose calculation algorithm using enhanced leaf modelling: Estimation based on small rectangular MLC fields Open
Background and Purpose Small field dosimetry plays a critical role in stereotactic radiotherapy, particularly for elongated fields shaped by multileaf collimators (MLCs). This study aims to optimize the Effective Spot Size (ESS) parameters…
View article: Species-specific N-glycan patterns in animal and human breast milk samples
Species-specific N-glycan patterns in animal and human breast milk samples Open
The main components of milk are protein, fat and carbohydrates. Glycans are complex carbohydrate structures covalently bound to proteins and lipids or exist freely in solutions. The function of glycans in nature is to contribute to structu…
View article: PIPELINE FOR MEASURING RESIDUAL TUMOUR VOLUME IN PATIENTS WITH GLIOBLASTOMA BASED ON A DIFFUSION TENSOR TISSUE SIGNATURE
PIPELINE FOR MEASURING RESIDUAL TUMOUR VOLUME IN PATIENTS WITH GLIOBLASTOMA BASED ON A DIFFUSION TENSOR TISSUE SIGNATURE Open
AIMS Glioblastoma is the most common malignant primary brain tumour in adults. It has a poor prognosis despite surgery and chemoradiotherapy. Extent of resection is an important modifiable prognostic factor. The latest Response Assessment i…
View article: Two‐step beam geometry optimization for volumetric modulated arc therapy gantry angles in breast treatments
Two‐step beam geometry optimization for volumetric modulated arc therapy gantry angles in breast treatments Open
Background In partial arc volumetric modulated arc therapy (VMAT) for treating breast cancer, setting up the limiting gantry positions of the treatment machine is a nontrivial yet repetitive and time‐consuming task during planning. Templat…
View article: Small elongated MLC fields: Novel equivalent square field formula and output factors
Small elongated MLC fields: Novel equivalent square field formula and output factors Open
Purpose This study evaluates different approaches for estimating the equivalent square field size (ESF) to derive the Output Correction Factors (OCF) according to the IAEA TRS‐483 protocol, for small fields, focusing on rectangular fields …
View article: Cardiac Exposure Related to Adjuvant Radiotherapy in Patients Affected by Thymoma: A Dosimetric Comparison of Photon or Proton Intensity-Modulated Therapy
Cardiac Exposure Related to Adjuvant Radiotherapy in Patients Affected by Thymoma: A Dosimetric Comparison of Photon or Proton Intensity-Modulated Therapy Open
Background: Radiotherapy for thymoma is delivered post-operatively in selected cases. Given the particular location of the thymic bed and the excellent prognosis, late cardiac toxicities may be an issue. The purpose of this retrospective d…
View article: Evaluation of ion recombination and polarity effect on photon depth dose measurements using mini‐ and micro‐ion chamber
Evaluation of ion recombination and polarity effect on photon depth dose measurements using mini‐ and micro‐ion chamber Open
Purpose To investigate the effect of ion recombination () and polarity () correction factors on percentage depth dose (PDD) curves for three ion chambers, using flat and flattening filter free (FFF) beams, across different broad field size…
View article: Dataset related to article "Knowledge-based DVH estimation and optimization for breast VMAT plans with and without avoidance sectors"
Dataset related to article "Knowledge-based DVH estimation and optimization for breast VMAT plans with and without avoidance sectors" Open
<p>This record contains raw data related to article "Knowledge-based DVH estimation and optimization for breast VMAT plans with and without avoidance sectors"</p><p><strong> Abstract</strong></p><…
View article: Dataset related to article "Predictive value of clinical and radiomic features for radiation therapy response in patients with lymph node-positive head and neck cancer"
Dataset related to article "Predictive value of clinical and radiomic features for radiation therapy response in patients with lymph node-positive head and neck cancer" Open
<p><strong> Abstract</strong></p><p>Background: Prediction of survival and radiation therapy response is challenging in head and neck cancer with metastatic lymph nodes (LNs). Here we developed novel radi…
View article: Dataset related to article "Stereotactic Body Radiation Therapy for Lung Metastases From Sarcoma in Oligometastatic Patients: A Phase 2 Study"
Dataset related to article "Stereotactic Body Radiation Therapy for Lung Metastases From Sarcoma in Oligometastatic Patients: A Phase 2 Study" Open
<p>This record contains raw data related to article "Stereotactic Body Radiation Therapy for Lung Metastases From Sarcoma in Oligometastatic Patients: A Phase 2 Study"</p><p>Abstract</p><p><strong>Purpos…
View article: Dataset related to article "Radiosurgery of limited brain metastases from primary solid tumor: results of the randomized phase III trial (NCT02355613) comparing treatments executed with a specialized or a C-arm linac-based platform"
Dataset related to article "Radiosurgery of limited brain metastases from primary solid tumor: results of the randomized phase III trial (NCT02355613) comparing treatments executed with a specialized or a C-arm linac-based platform" Open
<p>This record contains raw data related to article "Radiosurgery of limited brain metastases from primary solid tumor: results of the randomized phase III trial (NCT02355613) comparing treatments executed with a specialized or a C-a…
View article: Dataset related to article "The pattern of failure after Stereotactic Radiation Therapy (SRT) for oligo-metastases: predictive factors for poly-progression "
Dataset related to article "The pattern of failure after Stereotactic Radiation Therapy (SRT) for oligo-metastases: predictive factors for poly-progression " Open
This record contains raw data related to article "The pattern of failure after Stereotactic Radiation Therapy (SRT) for oligo-metastases: predictive factors for poly-progression"AbstractPurpose: Patients with oligo-metastatic disease (OMD)…
View article: Comparative dosimetric analysis of volumetric modulated arc therapy based craniospinal irradiation plans between Halcyon ring gantry and TrueBeam C-arm linear accelerator
Comparative dosimetric analysis of volumetric modulated arc therapy based craniospinal irradiation plans between Halcyon ring gantry and TrueBeam C-arm linear accelerator Open
This study evaluates the volumetric modulated arc therapy (VMAT) dosimetric comparison between Halcyon ring gantry and TrueBeam c-arm linear accelerators for craniospinal irradiation (CSI) of the neuro-axis. 25 patients, who received treat…
View article: Predictive value of clinical and radiomic features for radiation therapy response in patients with lymph node‐positive head and neck cancer
Predictive value of clinical and radiomic features for radiation therapy response in patients with lymph node‐positive head and neck cancer Open
Background Prediction of survival and radiation therapy response is challenging in head and neck cancer with metastatic lymph nodes (LNs). Here we developed novel radiomics‐ and clinical‐based predictive models. Methods Volumes of interest…
View article: Dataset related to article "Radiomics-based prognosis classification for high-risk prostate cancer treated with radiotherapy "
Dataset related to article "Radiomics-based prognosis classification for high-risk prostate cancer treated with radiotherapy " Open
This record contains raw data related to article “Radiomics-based prognosis classification for high-risk prostate cancer treated with radiotherapy" Abstract: Objective: The present study aimed to investigate if CT-based radiomics features…
View article: Dataset related to article "Radiomics-based prognosis classification for high-risk prostate cancer treated with radiotherapy "
Dataset related to article "Radiomics-based prognosis classification for high-risk prostate cancer treated with radiotherapy " Open
This record contains raw data related to article “Radiomics-based prognosis classification for high-risk prostate cancer treated with radiotherapy" Abstract: Objective: The present study aimed to investigate if CT-based radiomics features…
View article: The pattern of failure after Stereotactic Radiation Therapy (SRT) for oligometastases: predictive factors for poly progression
The pattern of failure after Stereotactic Radiation Therapy (SRT) for oligometastases: predictive factors for poly progression Open
Purpose Patients with oligometastatic disease (OMD) can be safely treated with Stereotactic Radiation Therapy (SRT). Further disease progression is common in these patients. In most cases, patients relapse again with oligometastases, howev…
View article: Training and validation of a knowledge-based dose-volume histogram predictive model in the optimisation of intensity-modulated proton and volumetric modulated arc photon plans for pleural mesothelioma patients
Training and validation of a knowledge-based dose-volume histogram predictive model in the optimisation of intensity-modulated proton and volumetric modulated arc photon plans for pleural mesothelioma patients Open
Background To investigate the performance of a narrow-scope knowledge-based RapidPlan (RP) model for optimisation of intensity-modulated proton therapy (IMPT) and volumetric modulated arc therapy (VMAT) plans applied to patients with pleur…
View article: Dataset related to article "Long term results of a phase II trial of hypofractionated adjuvant radiotherapy for early-stage breast cancer with volumetric modulated arc therapy and simultaneous integrated boost "
Dataset related to article "Long term results of a phase II trial of hypofractionated adjuvant radiotherapy for early-stage breast cancer with volumetric modulated arc therapy and simultaneous integrated boost " Open
This record contains raw data related to article “Long term results of a phase II trial of hypofractionated adjuvant radiotherapy for early-stage breast cancer with volumetric modulated arc therapy and simultaneous integrated boost" Purpos…
View article: Dataset related to article "Long term results of a phase II trial of hypofractionated adjuvant radiotherapy for early-stage breast cancer with volumetric modulated arc therapy and simultaneous integrated boost "
Dataset related to article "Long term results of a phase II trial of hypofractionated adjuvant radiotherapy for early-stage breast cancer with volumetric modulated arc therapy and simultaneous integrated boost " Open
This record contains raw data related to article “Long term results of a phase II trial of hypofractionated adjuvant radiotherapy for early-stage breast cancer with volumetric modulated arc therapy and simultaneous integrated boost" Purpos…
View article: A novel external beam radiotherapy method for cervical cancer patients using virtual straight or bending boost areas; an in-silico feasibility study
A novel external beam radiotherapy method for cervical cancer patients using virtual straight or bending boost areas; an in-silico feasibility study Open
Aim To investigate the potential role of a novel spatially fractionated radiation therapy (SFRT) method where heterogeneous dose patterns are created in target areas with virtual rods, straight or curving, of variable position, diameter, s…