F. Roblot
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View article: Guidelines for Lyme borreliosis: treatment
Guidelines for Lyme borreliosis: treatment Open
The aim of the clinical practice guideline is to support healthcare professionals in the diagnosis and management of patients with proven or suspected Lyme borreliosis (LB). The guideline provides an evidence-based algorithm for antibiotic…
View article: Prediction of higher ceftazidime–avibactam concentrations in the human renal interstitium compared with unbound plasma using a minimal physiologically based pharmacokinetic model developed in rats and pigs through microdialysis
Prediction of higher ceftazidime–avibactam concentrations in the human renal interstitium compared with unbound plasma using a minimal physiologically based pharmacokinetic model developed in rats and pigs through microdialysis Open
Last resort antibiotics, like ceftazidime–avibactam (CZA), were used to treat urinary tract infections caused by multidrug-resistant bacteria. However, no data on tissue distribution were available. Our aim was to describe the in vivo kidn…
View article: One year of SARS-CoV-2 circulation in the Nouvelle-Aquitaine region, February 2021–2022, France
One year of SARS-CoV-2 circulation in the Nouvelle-Aquitaine region, February 2021–2022, France Open
Background Since 2021, 3 variants of concern (VOC) have spread to France, causing successive epidemic waves. Objectives To describe the features of Alpha, Delta and Omicron VOC circulation in the Nouvelle-Aquitaine region, France, between …
View article: Outcome of febrile neutropenic patients treated for bacteriuria in hematology
Outcome of febrile neutropenic patients treated for bacteriuria in hematology Open
View article: Discussions of Antibiotic Resistance on Social Media Platforms: Text Mining and Mixed Methods Content Analysis Study
Discussions of Antibiotic Resistance on Social Media Platforms: Text Mining and Mixed Methods Content Analysis Study Open
Background With the increasing popularity of web 2.0 apps, social media has made it possible for individuals to post messages on antibiotic ineffectiveness. In such online conversations, patients discuss their quality of life (QoL). Social…
View article: Avis relatif à la conduite à tenir pour les cas confirmés d’infection àMonkeypox virus (MPXV) à risque de forme grave et pour lespersonnes contacts à risque d’infection par MPXV: AVIS du HCSP
Avis relatif à la conduite à tenir pour les cas confirmés d’infection àMonkeypox virus (MPXV) à risque de forme grave et pour lespersonnes contacts à risque d’infection par MPXV: AVIS du HCSP Open
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View article: Risk factors for biliary stent infections in malignant biliary obstruction secondary to unresectable malignancies
Risk factors for biliary stent infections in malignant biliary obstruction secondary to unresectable malignancies Open
View article: Social Media Platforms Listening Study on Antibiotic Resistance: Quantitative and Qualitative Findings (Preprint)
Social Media Platforms Listening Study on Antibiotic Resistance: Quantitative and Qualitative Findings (Preprint) Open
BACKGROUND With the increasing popularity of Web 2.0 applications, social media has made it possible for individuals to post messages on antibiotic ineffectiveness. In such online conversations, patients discuss their quality of life. Soc…
View article: Outcome of Febrile Neutropenic Patients Treated for Bacteriuria in Hematology
Outcome of Febrile Neutropenic Patients Treated for Bacteriuria in Hematology Open
IntroductionPositive urine sample is a frequent finding in post-chemotherapy febrile neutropenia (FN) and can lead to prolonged antibiotic therapy. The aim of this study was to assess the outcome of bacteriuria episodes in FN patients rece…
View article: Efficacy of antibiotic short course for bloodstream infections in acute myeloid leukemia patients with febrile neutropenia: A retrospective comparative study
Efficacy of antibiotic short course for bloodstream infections in acute myeloid leukemia patients with febrile neutropenia: A retrospective comparative study Open
View article: Late Onset of Chronic Granulomatous Disease Revealed by Paecilomyces lilacinus Cutaneous Infection
Late Onset of Chronic Granulomatous Disease Revealed by Paecilomyces lilacinus Cutaneous Infection Open
Chronic granulomatous disease (CGD) is an inherited immunodeficiency due to defective leukocyte NADPH responsible for recurrent infections and aberrant inflammation. Mutations in the CYBB gene are responsible for the X-linked CGD and accou…
View article: Post-herpetic encephalitis cerebral abscess: Viral reactivation or latency site within central nervous system?
Post-herpetic encephalitis cerebral abscess: Viral reactivation or latency site within central nervous system? Open
View article: Late-Onset of Chronic Granulomatous Disease Revealed By Paecilomyces Lilacinus Cutaneous Infection
Late-Onset of Chronic Granulomatous Disease Revealed By Paecilomyces Lilacinus Cutaneous Infection Open
Chronic granulomatous disease (CGD) is an inherited immunodeficiency due to defective leukocyte NADPH responsible for recurrent infections and aberrant inflammation. Mutations in the CYBB gene are responsible for the X-linked CGD and accou…
View article: Chlorhexidine plus alcohol versus povidone iodine plus alcohol, combined or not with innovative devices, for prevention of short-term peripheral venous catheter infection and failure (CLEAN 3 study): an investigator-initiated, open-label, single centre, randomised-controlled, two-by-two factorial trial
Chlorhexidine plus alcohol versus povidone iodine plus alcohol, combined or not with innovative devices, for prevention of short-term peripheral venous catheter infection and failure (CLEAN 3 study): an investigator-initiated, open-label, single centre, randomised-controlled, two-by-two factorial trial Open
View article: Why Methodology Is Important: Coffee as a Candidate Treatment for COVID-19?
Why Methodology Is Important: Coffee as a Candidate Treatment for COVID-19? Open
Background: During this pandemic situation, some studies have led to hasty conclusions about Corona Virus Disease-19 (COVID-19) treatment, due to a lack of methodology. This pedagogic study aimed to highlight potential biases in research o…
View article: Trends in Antibiotic Consumption and Resistance in France Over 20 Years: Large and Continuous Efforts but Contrasting Results
Trends in Antibiotic Consumption and Resistance in France Over 20 Years: Large and Continuous Efforts but Contrasting Results Open
Background Antimicrobial resistance (AMR) is a serious threat to humanity. This paper describes the French efforts made since 2001 and presents data on antimicrobial consumption (AC) and AMR. Methods We gathered all data on AC and AMR reco…
View article: Effet de la 1,3,7-Trimethylxanthine en cas de maladie COVID-19. Étude bicentrique comparative : réduction de la durée d’hospitalisation
Effet de la 1,3,7-Trimethylxanthine en cas de maladie COVID-19. Étude bicentrique comparative : réduction de la durée d’hospitalisation Open
View article: Blood glucose levels and COVID-19. Reply to Sardu C, D’Onofrio N, Balestrieri ML et al [letter] and Lepper PM, Bals R, Jüni P et al [letter]
Blood glucose levels and COVID-19. Reply to Sardu C, D’Onofrio N, Balestrieri ML et al [letter] and Lepper PM, Bals R, Jüni P et al [letter] Open
View article: Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO study
Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO study Open
View article: Observational study of vaccination in cancer patients: How can vaccine coverage be improved?
Observational study of vaccination in cancer patients: How can vaccine coverage be improved? Open
View article: Vaccination of cancer patients treated with chemotherapy: A survey among general practitioners
Vaccination of cancer patients treated with chemotherapy: A survey among general practitioners Open
View article: Overcoming stability challenges during continuous intravenous administration of high-dose amoxicillin using portable elastomeric pumps
Overcoming stability challenges during continuous intravenous administration of high-dose amoxicillin using portable elastomeric pumps Open
While treatment of serious infectious diseases may require high-dose amoxicillin, continuous infusion may be limited by lack of knowledge regarding the chemical stability of the drug. Therefore, we have performed a comprehensive study so a…
View article: Lyme borreliosis and other tick-borne diseases. Guidelines from the French scientific societies (II). Biological diagnosis, treatment, persistent symptoms after documented or suspected Lyme borreliosis
Lyme borreliosis and other tick-borne diseases. Guidelines from the French scientific societies (II). Biological diagnosis, treatment, persistent symptoms after documented or suspected Lyme borreliosis Open
View article: Lyme borreliosis and other tick-borne diseases. Guidelines from the French Scientific Societies (I): prevention, epidemiology, diagnosis
Lyme borreliosis and other tick-borne diseases. Guidelines from the French Scientific Societies (I): prevention, epidemiology, diagnosis Open
View article: Prognosis of Streptococcus pneumoniae endocarditis in France, a multicenter observational study (2000–2015)
Prognosis of Streptococcus pneumoniae endocarditis in France, a multicenter observational study (2000–2015) Open
View article: Review of European and American guidelines for the diagnosis of Lyme borreliosis
Review of European and American guidelines for the diagnosis of Lyme borreliosis Open
View article: Metrics to assess the quantity of antibiotic use in the outpatient setting: a systematic review followed by an international multidisciplinary consensus procedure
Metrics to assess the quantity of antibiotic use in the outpatient setting: a systematic review followed by an international multidisciplinary consensus procedure Open
A small set of consensually validated metrics to assess the quantity of antibiotic use in the outpatient setting was obtained, enabling (inter)national comparisons. The OQMs will help build a global conceptual framework for responsible ant…
View article: Quality indicators assessing antibiotic use in the outpatient setting: a systematic review followed by an international multidisciplinary consensus procedure
Quality indicators assessing antibiotic use in the outpatient setting: a systematic review followed by an international multidisciplinary consensus procedure Open
We identified a set of 32 outpatient QIs to measure the appropriateness of antibiotic use. These QIs can be used to identify targets for improvement and to evaluate the effects of antibiotic stewardship interventions.
View article: Osteoarticular manifestations of Q fever: a case series and literature review
Osteoarticular manifestations of Q fever: a case series and literature review Open
View article: Thrombosis and antiphospholipid antibody syndrome during acute Q fever
Thrombosis and antiphospholipid antibody syndrome during acute Q fever Open
Q fever is a neglected and potentially fatal disease. During acute Q fever, antiphospholipid antibodies are very prevalent and have been associated with fever, thrombocytopenia, acquired heart valve disease, and progression to chronic endo…