Fabian Grabenhorst
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View article: Preferences for fat, sugar, and oral-sensory food qualities in monkeys and humans
Preferences for fat, sugar, and oral-sensory food qualities in monkeys and humans Open
In humans and other primates, food intake depends on sophisticated, individualized preferences for nutrients and oral-sensory food qualities that guide decision-making and eating behavior. The neural and behavioral mechanisms for such prim…
View article: Value coding by primate amygdala neurons complies with economic choice theory
Value coding by primate amygdala neurons complies with economic choice theory Open
Primate amygdala neurons are implicated in coding the value of choice options for decision-making. However, it remains unclear whether amygdala value signals comply with the notion that decision makers maximize the value of rewards, as for…
View article: Dynamic coding and sequential integration of multiple reward attributes by primate amygdala neurons
Dynamic coding and sequential integration of multiple reward attributes by primate amygdala neurons Open
The value of visual stimuli guides learning, decision-making, and motivation. Although stimulus values often depend on multiple attributes, how neurons extract and integrate distinct value components from separate cues remains unclear. Her…
View article: The amygdala and the pursuit of future rewards
The amygdala and the pursuit of future rewards Open
The successful pursuit of future rewards requires forming an internal goal, followed by planning, decision-making, and progress-tracking over multiple steps. The initial step—forming goals and the plans for obtaining them—involves the subj…
View article: Perception of Motivational Type in Social Partners
Perception of Motivational Type in Social Partners Open
The quality of one’s motivation has long been established as an essential component to goal pursuit, subjective wellbeing, and other life outcomes. However, how people perceive the motivational type of social others remains poorly understo…
View article: Social Risk Coding by Amygdala Activity and Connectivity with the Dorsal Anterior Cingulate Cortex
Social Risk Coding by Amygdala Activity and Connectivity with the Dorsal Anterior Cingulate Cortex Open
Risk is a fundamental factor affecting individual and social economic decisions, but its neural correlates are largely unexplored in the social domain. The amygdala, together with the dorsal anterior cingulate cortex (dACC), is thought to …
View article: Social risk coding by amygdala activity and connectivity with dorsal anterior cingulate cortex
Social risk coding by amygdala activity and connectivity with dorsal anterior cingulate cortex Open
Risk is a fundamental factor affecting individual and social economic decisions, but its neural correlates are largely unexplored in the social domain. The amygdala, together with the dorsal anterior cingulate cortex (dACC), is thought to …
View article: Dynamic coding and sequential integration of multiple reward attributes by primate amygdala neurons
Dynamic coding and sequential integration of multiple reward attributes by primate amygdala neurons Open
The value of visual stimuli guides learning, decision-making and motivation. Although stimulus values often depend on multiple attributes, how neurons extract and integrate distinct value components from separate cues remains unclear. Here…
View article: A Neural Mechanism in the Human Orbitofrontal Cortex for Preferring High-Fat Foods Based on Oral Texture
A Neural Mechanism in the Human Orbitofrontal Cortex for Preferring High-Fat Foods Based on Oral Texture Open
Although overconsumption of high-fat foods is a major driver of weight gain, the neural mechanisms that link the oral sensory properties of dietary fat to reward valuation and eating behavior remain unclear. Here we combine novel food-engi…
View article: Nutrient-Sensitive Reinforcement Learning in Monkeys
Nutrient-Sensitive Reinforcement Learning in Monkeys Open
In reinforcement learning (RL), animals choose by assigning values to options and learn by updating these values from reward outcomes. This framework has been instrumental in identifying fundamental learning variables and their neuronal im…
View article: Mechanisms of adjustments to different types of uncertainty in the reward environment across mice and monkeys
Mechanisms of adjustments to different types of uncertainty in the reward environment across mice and monkeys Open
Despite being unpredictable and uncertain, reward environments often exhibit certain regularities, and animals navigating these environments try to detect and utilize such regularities to adapt their behavior. However, successful learning …
View article: Preferences for nutrients and sensory food qualities identify biological sources of economic values in monkeys
Preferences for nutrients and sensory food qualities identify biological sources of economic values in monkeys Open
Significance Preferences for foods high in sugar and fat are near universal and major contributors to obesity. Additionally, human food choices are sophisticated and individualistic: we choose by evaluating a food’s nutrients and sensory f…
View article: Nutrient-sensitive reinforcement learning in monkeys
Nutrient-sensitive reinforcement learning in monkeys Open
Animals make adaptive food choices to acquire nutrients that are essential for survival. In reinforcement learning (RL), animals choose by assigning values to options and update these values with new experiences. This framework has been in…
View article: Single-Dimensional Human Brain Signals for Two-Dimensional Economic Choice Options
Single-Dimensional Human Brain Signals for Two-Dimensional Economic Choice Options Open
Rewarding choice options typically contain multiple components, but neural signals in single brain voxels are scalar and primarily vary up or down. In a previous study, we had designed reward bundles that contained the same two milkshakes …
View article: Nonhuman Primates Satisfy Utility Maximization in Compliance with the Continuity Axiom of Expected Utility Theory
Nonhuman Primates Satisfy Utility Maximization in Compliance with the Continuity Axiom of Expected Utility Theory Open
Expected Utility Theory (EUT), the first axiomatic theory of risky choice, describes choices as a utility maximization process: decision makers assign a subjective value (utility) to each choice option and choose the one with the highest u…
View article: Experimentally revealed stochastic preferences for multicomponent choice options.
Experimentally revealed stochastic preferences for multicomponent choice options. Open
Realistic, everyday rewards contain multiple components. An apple has taste and size. However, we choose in single dimensions, simply preferring some apples to others. How can such single-dimensional preference relationships refer to multi…
View article: Single-dimensional human brain signals for two-dimensional economic choice options
Single-dimensional human brain signals for two-dimensional economic choice options Open
Rewarding choice options typically contain multiple components, but neural signals in single brain voxels are scalar and primarily vary up or down. In a previous study, we had designed reward bundles that contained the same two milkshakes …
View article: Non-human primates satisfy utility maximization in compliance with the continuity axiom of Expected Utility Theory
Non-human primates satisfy utility maximization in compliance with the continuity axiom of Expected Utility Theory Open
Expected Utility Theory (EUT), the first axiomatic theory of risky choice, describes choices as a utility maximization process: decision makers assign a subjective value (utility) to each choice option and choose the one with the highest u…
View article: Neural activity in human ventromedial prefrontal cortex reflecting the intention to save reward
Neural activity in human ventromedial prefrontal cortex reflecting the intention to save reward Open
Saving behavior usually requires individuals to perform several consecutive choices before collecting the final reward. The overt behavior is preceded by an intention to perform an appropriate choice sequence. We studied saving sequences f…
View article: Primate prefrontal neurons signal economic risk derived from the statistics of recent reward experience
Primate prefrontal neurons signal economic risk derived from the statistics of recent reward experience Open
Risk derives from the variation of rewards and governs economic decisions, yet how the brain calculates risk from the frequency of experienced events, rather than from explicit risk-descriptive cues, remains unclear. Here, we investigated …
View article: Neural Mechanisms for Accepting and Rejecting Artificial Social Partners in the Uncanny Valley
Neural Mechanisms for Accepting and Rejecting Artificial Social Partners in the Uncanny Valley Open
Artificial agents are becoming prevalent across human life domains. However, the neural mechanisms underlying human responses to these new, artificial social partners remain unclear. The uncanny valley (UV) hypothesis predicts that humans …