Fabiano Bini
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View article: Shear viscosity assessment in nanoconfined water inside 3D model human mineralized collagen fibril
Shear viscosity assessment in nanoconfined water inside 3D model human mineralized collagen fibril Open
This work presents a 3D numerical model of the human mineralized collagen fibril developed to quantitatively analyse the shear viscosity and diffusion of nanoconfined water within bone tissue at the nanoscale based on a 3D random walk appr…
View article: 117P Total tumor load by OSNA and nomogram-based prediction of extensive nodal involvement in early breast cancer
117P Total tumor load by OSNA and nomogram-based prediction of extensive nodal involvement in early breast cancer Open
View article: Extended Reality-Based Proof-of-Concept for Clinical Assessment Balance and Postural Disorders for Personalized Innovative Protocol
Extended Reality-Based Proof-of-Concept for Clinical Assessment Balance and Postural Disorders for Personalized Innovative Protocol Open
Background: Clinical assessment of balance and postural disorders is usually carried out through several common practices including tests such as the Subjective Visual Vertical (SVV) and Limit of Stability (LOS). Nowadays, several cutting-…
View article: Applying a Virtual Art Therapy System Based on the Michelangelo Effect in Patients with Spinal Cord Injury
Applying a Virtual Art Therapy System Based on the Michelangelo Effect in Patients with Spinal Cord Injury Open
Background: Serious videogames have already demonstrated their positive impact on rehabilitation and of particular interest is the virtual reality (VR) technology. This immersive technology has been used in this study to create a neuroaest…
View article: Lifestyle, environment and other major determinants of frailty in older adults: a population-based study from the UK Biobank
Lifestyle, environment and other major determinants of frailty in older adults: a population-based study from the UK Biobank Open
Frailty is a geriatric multidimensional syndrome characterized by a loss of physiologic reserves and disproportionate vulnerability to external stressors and associated with increased risk of multiple negative health outcomes. Since frailt…
View article: Extended Reality-based Proof-of-Concept to Clinical Assessment Balance and Postural Disorders for Personalized Innovative Protocol
Extended Reality-based Proof-of-Concept to Clinical Assessment Balance and Postural Disorders for Personalized Innovative Protocol Open
Background Clinical assessment of balance and postural disorders is usually carried out through several common practices including tests such as Subjective Visual Vertical (SVV) and Limit of Stability (LOS). Nowadays several cutting-edge t…
View article: Comparative Evaluation of Machine Learning-Based Radiomics and Deep Learning for Breast Lesion Classification in Mammography
Comparative Evaluation of Machine Learning-Based Radiomics and Deep Learning for Breast Lesion Classification in Mammography Open
Background: Breast cancer is the second leading cause of cancer-related mortality among women, accounting for 12% of cases. Early diagnosis, based on the identification of radiological features, such as masses and microcalcifications in ma…
View article: Applying a Virtual Art Therapy System based on the Michelangelo Effect in Patients with Spinal Cord Injury
Applying a Virtual Art Therapy System based on the Michelangelo Effect in Patients with Spinal Cord Injury Open
Background: serious videogames have already demonstrated their positive impact on rehabilitation and of particular interest is the virtual reality (VR) technology. This immersive technology has been used in this study for a neuroaesthetic …
View article: Comparative Evaluation of Machine Learning-Based Radiomics and Deep Learning for Breast Lesion Classification in Mammography
Comparative Evaluation of Machine Learning-Based Radiomics and Deep Learning for Breast Lesion Classification in Mammography Open
Background: Breast cancer is the second leading cause of cancer-related mortality among women, accounting for 12% of cases. Early diagnosis, based on the identifica-tion of radiological features such as masses and microcalcifications in ma…
View article: [18F]PSMA-1007 PET/CT-based radiomics may help enhance the interpretation of bone focal uptakes in hormone-sensitive prostate cancer patients
[18F]PSMA-1007 PET/CT-based radiomics may help enhance the interpretation of bone focal uptakes in hormone-sensitive prostate cancer patients Open
Purpose We hypothesised that applying radiomics to [ 18 F]PSMA-1007 PET/CT images could help distinguish Unspecific Bone Uptakes (UBUs) from bone metastases in prostate cancer (PCa) patients. We compared the performance of radiomic feature…
View article: An HTA systems decision-support toolbox for short and long-term healthcare and economic perspectives in an Italian hospital
An HTA systems decision-support toolbox for short and long-term healthcare and economic perspectives in an Italian hospital Open
Objectives The introduction of a new healthcare technology within the technological facilities of a hospital is a complex action that must go through the mandatory decision-making process of health technology assessment (HTA). Nowadays, de…
View article: Implementation of Automatic Segmentation Framework as Preprocessing Step for Radiomics Analysis of Lung Anatomical Districts
Implementation of Automatic Segmentation Framework as Preprocessing Step for Radiomics Analysis of Lung Anatomical Districts Open
Background: The advent of artificial intelligence has significantly impacted radiology, with radiomics emerging as a transformative approach that extracts quantitative data from medical images to improve diagnostic and therapeutic accuracy…
View article: Preclinical Implementation of matRadiomics: A Case Study for Early Malformation Prediction in Zebrafish Model
Preclinical Implementation of matRadiomics: A Case Study for Early Malformation Prediction in Zebrafish Model Open
Radiomics provides a structured approach to support clinical decision-making through key steps; however, users often face difficulties when switching between various software platforms to complete the workflow. To streamline this process, …
View article: Breakthrough and Challenging Application: Mixed Reality-Assisted Intracardiac Surgery
Breakthrough and Challenging Application: Mixed Reality-Assisted Intracardiac Surgery Open
Background: While several studies investigate the utility and clinical value of 3D printing in aiding diagnosis, medical education, preoperative planning, and intraoperative guidance of surgical interventions, there is a scarcity of litera…
View article: Mixed Reality-Based Smart Occupational Therapy Personalized Protocol for Cerebellar Ataxic Patients
Mixed Reality-Based Smart Occupational Therapy Personalized Protocol for Cerebellar Ataxic Patients Open
Background: Occupational therapy (OT) is an essential component of patient care, and it is especially beneficial if focused on meaningful activities. For ataxic patients, traditional procedures are currently the most efficient, although wi…
View article: Jingle Cell Rock: Steering Cellular Activity With Low-Intensity Pulsed Ultrasound (LIPUS) to Engineer Functional Tissues in Regenerative Medicine
Jingle Cell Rock: Steering Cellular Activity With Low-Intensity Pulsed Ultrasound (LIPUS) to Engineer Functional Tissues in Regenerative Medicine Open
View article: Mixed Reality as High Assistive Technological Impact on the Quality of Life in the Elderly Population
Mixed Reality as High Assistive Technological Impact on the Quality of Life in the Elderly Population Open
Since in the decade 2021-2030 an increase in the elderly population has already been predicted, the introduction of new assistive technologies specifically designed for elderly people living alone or in nursing home is essential to preserv…
View article: Optimizing Rare Disease Gait Classification through Data Balancing and Generative AI: Insights from Hereditary Cerebellar Ataxia
Optimizing Rare Disease Gait Classification through Data Balancing and Generative AI: Insights from Hereditary Cerebellar Ataxia Open
The interpretability of gait analysis studies in people with rare diseases, such as those with primary hereditary cerebellar ataxia (pwCA), is frequently limited by the small sample sizes and unbalanced datasets. The purpose of this study …
View article: Michelangelo Effect in Cognitive Rehabilitation: Using Art in a Digital Visuospatial Memory Task
Michelangelo Effect in Cognitive Rehabilitation: Using Art in a Digital Visuospatial Memory Task Open
The Michelangelo effect is a phenomenon that shows a reduction in perceived effort and an improvement in performance among both healthy subjects and patients when completing a motor task related to artistic stimuli, compared to performing …
View article: Development and Implementation of an Innovative Framework for Automated Radiomics Analysis in Neuroimaging
Development and Implementation of an Innovative Framework for Automated Radiomics Analysis in Neuroimaging Open
Radiomics represents an innovative approach to medical image analysis, enabling comprehensive quantitative evaluation of radiological images through advanced image processing and Machine or Deep Learning algorithms. This technique uncovers…
View article: Michelangelo Effect in Cognitive Rehabilitation: Using Art in a Digital Visuospatial Memory Task
Michelangelo Effect in Cognitive Rehabilitation: Using Art in a Digital Visuospatial Memory Task Open
Previous studies reported a reduction of the perceived effort and an improvement of the perfor-mances of healthy subjects and patients when a motor task was combined with artistic images with respect to non-artistic images. This phenomenon…
View article: Development of a microfluidic-assisted open-source 3D bioprinting system (MOS3S) for the engineering of hierarchical tissues
Development of a microfluidic-assisted open-source 3D bioprinting system (MOS3S) for the engineering of hierarchical tissues Open
View article: Endo-Surgical Force Feedback System Design for Virtual Reality Applications in Medical Planning
Endo-Surgical Force Feedback System Design for Virtual Reality Applications in Medical Planning Open
View article: Michelangelo Effect in Virtual Sculpturing: Prospective for Motor Neurorehabilitation in the Metaverse
Michelangelo Effect in Virtual Sculpturing: Prospective for Motor Neurorehabilitation in the Metaverse Open
We investigated the Michelangelo effect, i.e. the facilitatory effect of a virtual art therapy in motor rehabilitation (Iosa et al. 2021), with a novel virtual reality paradigm in which users are engaged in motor exercises with 3D sculptur…
View article: A Critical Analysis of the Robustness of Radiomics to Variations in Segmentation Methods in 18F-PSMA-1007 PET Images of Patients Affected by Prostate Cancer
A Critical Analysis of the Robustness of Radiomics to Variations in Segmentation Methods in 18F-PSMA-1007 PET Images of Patients Affected by Prostate Cancer Open
Background: Radiomics shows promising results in supporting the clinical decision process, and much effort has been put into its standardization, thus leading to the Imaging Biomarker Standardization Initiative (IBSI), that established how…
View article: Analysis of Connectome Graphs Based on Boundary Scale
Analysis of Connectome Graphs Based on Boundary Scale Open
The purpose of this work is to advance in the computational study of connectome graphs from a topological point of view. Specifically, starting from a sequence of hypergraphs associated to a brain graph (obtained using the Boundary Scale m…
View article: Model-Optimizing Radiofrequency Parameters of 3D Finite Element Analysis for Ablation of Benign Thyroid Nodules
Model-Optimizing Radiofrequency Parameters of 3D Finite Element Analysis for Ablation of Benign Thyroid Nodules Open
Radiofrequency (RF) ablation represents an efficient strategy to reduce the volume of thyroid nodules. In this study, a finite element model was developed with the aim of optimizing RF parameters, e.g., input power and treatment duration, …
View article: Is medical device regulatory compliance growing as fast as extended reality to avoid misunderstandings in the future?
Is medical device regulatory compliance growing as fast as extended reality to avoid misunderstandings in the future? Open
View article: Biomimetic 3D bioprinting approaches to engineer the tumor microenvironment
Biomimetic 3D bioprinting approaches to engineer the tumor microenvironment Open
With the increasing incidence and mortality rates, cancer remains a major health challenge in the world. Despite advances in therapies and clinical programs, the efficacy of anti-cancer drugs often fails to translate from pre-clinical mode…
View article: Harnessing Biofabrication Strategies to Re-Surface Osteochondral Defects: Repair, Enhance, and Regenerate
Harnessing Biofabrication Strategies to Re-Surface Osteochondral Defects: Repair, Enhance, and Regenerate Open
Osteochondral tissue (OC) is a complex and multiphasic system comprising cartilage and subchondral bone. The discrete OC architecture is layered with specific zones characterized by different compositions, morphology, collagen orientation,…