Fabien Dutreux
YOU?
Author Swipe
View article: Mining yeast diversity unveils novel targets for improved heterologous laccase production in Saccharomyces cerevisiae
Mining yeast diversity unveils novel targets for improved heterologous laccase production in Saccharomyces cerevisiae Open
View article: Multiple independent losses of crossover interference during yeast evolutionary history
Multiple independent losses of crossover interference during yeast evolutionary history Open
Meiotic recombination is essential for the accurate chromosome segregation and the generation of genetic diversity through crossover and gene conversion events. Although this process has been studied extensively in a few selected model spe…
View article: Mining Yeast Diversity Unveils Novel Targets for Improved Heterologous Laccase Production in<i>Saccharomyces cerevisiae</i>
Mining Yeast Diversity Unveils Novel Targets for Improved Heterologous Laccase Production in<i>Saccharomyces cerevisiae</i> Open
The budding yeast Saccharomyces cerevisiae is a widely utilized host cell for recombinant protein production due to its well studied and annotated genome, its ability to secrete large and post-translationally modified proteins, fast growth…
View article: Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast
Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast Open
View article: Recurrent loss of crossover interference punctuates the recombination landscape across yeast species
Recurrent loss of crossover interference punctuates the recombination landscape across yeast species Open
Meiotic recombination is essential for the accurate chromosome segregation and the generation of genetic diversity through crossover and gene conversion events. Although this process has been studied extensively in a few selected model spe…
View article: ScRAPv20230731: Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae
ScRAPv20230731: Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae Open
Saccharomyces cerevisiae Reference Assembly Panel (ScRAP) v20230731 > The haplotype-resolved and/or collapsed T2T genome assemblies for 142 S. cerevisiae strains isolated from diverse geographical and eco…
View article: Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae
Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae Open
View article: ScRAPv20230731: Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae
ScRAPv20230731: Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae Open
Saccharomyces cerevisiae Reference Assembly Panel (ScRAP) v20230731 > The haplotype-resolved and/or collapsed T2T genome assemblies for 142 S. cerevisiae strains isolated from diverse geographical and eco…
View article: Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast
Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast Open
Summary Gene expression is an essential step in the translation of genotypes into phenotypes. However, little is known about the transcriptome architecture and the underlying genetic effects at a species-level. Here, we generated and analy…
View article: Lessons from the meiotic recombination landscape of the ZMM deficient budding yeast Lachancea waltii
Lessons from the meiotic recombination landscape of the ZMM deficient budding yeast Lachancea waltii Open
Meiotic recombination is a driving force for genome evolution, deeply characterized in a few model species, notably in the budding yeast Saccharomyces cerevisiae . Interestingly, Zip2, Zip3, Zip4, Spo16, Msh4, and Msh5, members of the so-c…
View article: Loss of Heterozygosity Spectrum Depends on Ploidy Level in Natural Yeast Populations
Loss of Heterozygosity Spectrum Depends on Ploidy Level in Natural Yeast Populations Open
The appearance of genomic variations such as loss of heterozygosity (LOH) has a significant impact on phenotypic diversity observed in a population. Recent large-scale yeast population genomic surveys have shown a high frequency of these e…
View article: 142 telomere-to-telomere assemblies reveal the genome structural landscape in<i>Saccharomyces cerevisiae</i>
142 telomere-to-telomere assemblies reveal the genome structural landscape in<i>Saccharomyces cerevisiae</i> Open
SUMMARY As population genomics is transitioning from single reference genomes to pangenomes, major improvements in terms of genome contiguity, phylogenetic sampling, haplotype phasing and structural variant (SV) calling are required. Here,…
View article: Loss of heterozygosity spectrum varies with ploidy levels in natural yeast populations
Loss of heterozygosity spectrum varies with ploidy levels in natural yeast populations Open
The appearance of genomic variations such as loss of heterozygosity (LOH) has a significant impact on phenotypic diversity observed in a population. Recent large-scale yeast population genomic surveys have shown a high frequency of these e…
View article: Lessons from the meiotic recombination landscape of the ZMM deficient budding yeast <i>Lachancea waltii</i>
Lessons from the meiotic recombination landscape of the ZMM deficient budding yeast <i>Lachancea waltii</i> Open
Meiotic recombination has been deeply characterized in a few model species only, notably in the budding yeast Saccharomyces cerevisiae . Interestingly, most members of the ZMM pathway that implements meiotic crossover interference in S. ce…
View article: Sex without crossing over in the yeast Saccharomycodes ludwigii
Sex without crossing over in the yeast Saccharomycodes ludwigii Open
Background Intermixing of genomes through meiotic reassortment and recombination of homologous chromosomes is a unifying theme of sexual reproduction in eukaryotic organisms and is considered crucial for their adaptive evolution. Previous …
View article: Dissection of quantitative trait loci in the <i>Lachancea waltii</i> yeast species highlights major hotspots
Dissection of quantitative trait loci in the <i>Lachancea waltii</i> yeast species highlights major hotspots Open
Dissecting the genetic basis of complex trait remains a real challenge. The budding yeast Saccharomyces cerevisiae has become a model organism for studying quantitative traits, successfully increasing our knowledge in many aspects. However…
View article: Loss of heterozygosity results in rapid but variable genome homogenization across yeast genetic backgrounds
Loss of heterozygosity results in rapid but variable genome homogenization across yeast genetic backgrounds Open
The dynamics and diversity of the appearance of genetic variants play an essential role in the evolution of the genome and the shaping of biodiversity. Recent population-wide genome sequencing surveys have highlighted the importance of los…
View article: Author response: Loss of heterozygosity results in rapid but variable genome homogenization across yeast genetic backgrounds
Author response: Loss of heterozygosity results in rapid but variable genome homogenization across yeast genetic backgrounds Open
View article: Sex without crossing over in the yeast<i>Saccharomycodes ludwigii</i>
Sex without crossing over in the yeast<i>Saccharomycodes ludwigii</i> Open
Meiotic recombination is a ubiquitous function of sexual reproduction throughout eukaryotes. Here we report that recombination is extremely suppressed during meiosis in the yeast species Saccharomycodes ludwigii . DNA double-strand break f…
View article: Evolution of quantitative trait locus hotspots in yeast species
Evolution of quantitative trait locus hotspots in yeast species Open
Dissecting the genetic basis of complex trait remains a real challenge. The budding yeast Saccharomyces cerevisiae has become a model organism for studying quantitative traits, successfully increasing our knowledge in many aspects. However…
View article: ZMIZ1 Variants Cause a Syndromic Neurodevelopmental Disorder
ZMIZ1 Variants Cause a Syndromic Neurodevelopmental Disorder Open
View article: ZMIZ1 Variants Cause a Syndromic Neurodevelopmental Disorder
ZMIZ1 Variants Cause a Syndromic Neurodevelopmental Disorder Open
View article: De novo assembly and annotation of three Leptosphaeria genomes using Oxford Nanopore MinION sequencing
De novo assembly and annotation of three Leptosphaeria genomes using Oxford Nanopore MinION sequencing Open
View article: Transcriptomic datasets
Transcriptomic datasets Open
Description of the transcriptomic datasets (illumina) and the corresponding de novo assembly and alignments of RNA-Seq contigs.
View article: Duplicated genomic regions
Duplicated genomic regions Open
Description of the genomic regions that present duplicated genes and no proper read support.
View article: Genomic datasets
Genomic datasets Open
Description of the genomic datasets (nanopore and illumina).
View article: LeptoLife: deciphering the life and pathogenicity cycle of a fungal phytopathogen using metatranscriptomics
LeptoLife: deciphering the life and pathogenicity cycle of a fungal phytopathogen using metatranscriptomics Open
Leptosphaeria maculans, the agent of stem canker of oilseed rape (OSR, Brassica napus) displays an unusually complex pathogenic cycle and interactions with its host plant. Its life cycle encompasses a saprophytic stage on stem debris, duri…