Fabien Sassolas
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View article: Conservation and evolution of DNA sequence-mediated nucleosome positioning in eukaryotes
Conservation and evolution of DNA sequence-mediated nucleosome positioning in eukaryotes Open
Le nucléosome est un complexe d'histones et de ~150 bp d'ADN. C'est un constituant majeur de la chromatine chez les eucaryotes, couvrant 75 - 90% des génomes. Les histones sont présentes dans l'intégralité des eucaryotes analysés. Le posit…
View article: Decoding Nucleosome-Depleted Regions: Insights from Epigenetic Marks, Nucleosome Size, and Thermodynamic Modelling
Decoding Nucleosome-Depleted Regions: Insights from Epigenetic Marks, Nucleosome Size, and Thermodynamic Modelling Open
Elucidating the global and local rules that govern genome-wide nucleosome organisation and chromatin architecture remains a critical challenge. Thermodynamic modelling based on DNA elastic properties predicts the presence of sequence-encod…