Explanipedia

Biomimetic Model for Electromagnetic Modulation of Cardiovascular Cellular Interactions On-Chip Open

Ana C. Manjua, Fábio F. F. Garrudo, Ana Lúcia Agostinho, Afonso Gusmão, Paola Sanjuan‐Alberte , et al. · 2025

Cardiovascular diseases are the leading cause of global mortality. These conditions are associated with cardiac cell death and loss of vascularization, potentially progressing to fatal myocardial infarction. However, the lack of accurate m…

Wireless electrostimulation for cancer treatment: An integrated nanoparticle/coaxial fiber mesh platform Open

Leonor Resina, Fábio F. F. Garrudo, Carlos Alemán, Teresa Esteves, Frederico Castelo Ferreira · 2024

Direct coupled electrical stimulation towards improved osteogenic differentiation of human mesenchymal stem/stromal cells: a comparative study of different protocols Open

João C. Silva, Jo�ão Meneses, Fábio F. F. Garrudo, Sofia R. Fernandes, Nuno Alves , et al. · 2024

Electrical stimulation (ES) has been described as a promising tool for bone tissue engineering, being known to promote vital cellular processes such as cell proliferation, migration, and differentiation. Despite the high variability of app…

Synergy between 3D-extruded electroconductive scaffolds and electrical stimulation to improve bone tissue engineering strategies Open

João C. Silva, Pedro Marcelino, Jo�ão Meneses, Frederico Barbosa, Carla Moura , et al. · 2024

PCL-PEDOT:PSS electroconductive scaffolds were combined with electrical stimulation to enhance the osteogenic differentiation and mineralization of mesenchymal stem/stromal cells towards improved bone tissue engineering strategies.

Exploring Functionalized Magnetic Hydrogel Polyvinyl Alcohol and Chitosan Electrospun Nanofibers Open

Mónica Guerra, Fábio F. F. Garrudo, Célia Faustino, M. Emília Rosa, Maria H.L. Ribeiro · 2023

Nanofibrous materials present interesting characteristics, such as higher area/mass ratio and reactivity. These properties have been exploited in different applications, such as drug-controlled release and site-specific targeting of biomol…

Pseudo-doping effect on structural and electrical properties of polyaniline-camphorsulfonic acid Open

Fábio F. F. Garrudo, L.F. Vieira Ferreira, Ana Maria Ferraria, A.M. Botelho do Rego, Ana Charas , et al. · 2023

Electroconductive polymers (ECP) are critical for the design of soft electronic and bioelectronic devices. Polyaniline:camphorsulfonic acid (PANI:CSA) is an example of a biocompatible and affordable ECP, whose electroconductivity is highly…

Novel Electroactive Mineralized Polyacrylonitrile/PEDOT:PSS Electrospun Nanofibers for Bone Repair Applications Open

Frederico Barbosa, Fábio F. F. Garrudo, Ana C. Marques, Joaquim M. S. Cabral, Jorge Morgado , et al. · 2023

Bone defect repair remains a critical challenge in current orthopedic clinical practice, as the available therapeutic strategies only offer suboptimal outcomes. Therefore, bone tissue engineering (BTE) approaches, involving the development…

Hydroxyapatite-filled osteoinductive and piezoelectric nanofibers for bone tissue engineering Open

Frederico Barbosa, Fábio F. F. Garrudo, Paola Sanjuan‐Alberte, Leonor Resina, Marta S. Carvalho , et al. · 2023

Osteoporotic-related fractures are among the leading causes of chronic disease morbidity in Europe and in the US. While a significant percentage of fractures can be repaired naturally, in delayed-union and non-union fractures surgical inte…

Production of Blended Poly(acrylonitrile): Poly(ethylenedioxythiophene):Poly(styrene sulfonate) Electrospun Fibers for Neural Applications Open

Fábio F. F. Garrudo, Giulia Filippone, Leonor Resina, João C. Silva, Frederico Barbosa , et al. · 2023

This study describes, for the first time, the successful incorporation of poly(ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) in Poly(acrylonitrile) (PAN) fibers. While electroconductive PEDOT:PSS is extremely challenging to e…

Designing Electrical Stimulation Platforms for Neural Cell Cultivation Using Poly(aniline): Camphorsulfonic Acid Open

Fábio F. F. Garrudo, Robert J. Linhardt, Frederico Castelo Ferreira, Jorge Morgado · 2023

Electrical stimulation is a powerful strategy to improve the differentiation of neural stem cells into neurons. Such an approach can be implemented, in association with biomaterials and nanotechnology, for the development of new therapies …

Fabrication of Novel Electroconductive PAN/PEDOT:PSS Nanofibers for Osteochondral Tissue Regeneration Open

Frederico Barbosa, João C. Silva, Fábio F. F. Garrudo, Joaquim M. S. Cabral, Paula Pascoal‐Faria , et al. · 2022

first_page settings Order Article Reprints Font Type: Arial Georgia Verdana Font Size: Aa Aa Aa Line Spacing:    Column Width:    Background: Open AccessAbstract Fabrication of Novel Electroconductive PAN/PEDOT:PSS Nanofibers for Ost…

Novel Coaxial Fibers Combining Piezoelectrical and Electrical Conductive Polymers towards Cardiac Tissue Engineering Open

Mariana Ramalho Gomes, Fábio F. F. Garrudo, Paola Sanjuan‐Alberte, Frederico Castelo Ferreira · 2022

first_page settings Order Article Reprints Font Type: Arial Georgia Verdana Font Size: Aa Aa Aa Line Spacing:    Column Width:    Background: Open AccessAbstract Novel Coaxial Fibers Combining Piezoelectrical and Electrical Conductiv…

Piezoelectric PVDF-TrFE/Hydroxyapatite Nanofibers for Bone Tissue Engineering Open

Frederico Barbosa, Paola S. Alberte, Fábio F. F. Garrudo, Marta S. Carvalho, Paula Pascoal‐Faria , et al. · 2022

first_page settings Order Article Reprints Font Type: Arial Georgia Verdana Font Size: Aa Aa Aa Line Spacing:    Column Width:    Background: Open AccessAbstract Piezoelectric PVDF-TrFE/Hydroxyapatite Nanofibers for Bone Tissue Engin…

PEDOT:PSS-Coated Polybenzimidazole Electroconductive Nanofibers for Biomedical Applications Open

Laura Sordini, João C. Silva, Fábio F. F. Garrudo, Carlos A. V. Rodrigues, Ana C. Marques , et al. · 2021

Bioelectricity drives several processes in the human body. The development of new materials that can deliver electrical stimuli is gaining increasing attention in the field of tissue engineering. In this work, novel, highly electrically co…

Effect of Electrical Stimulation Conditions on Neural Stem Cells Differentiation on Cross-Linked PEDOT:PSS Films Open

Laura Sordini, Fábio F. F. Garrudo, Carlos A. V. Rodrigues, Robert J. Linhardt, Joaquim M. S. Cabral , et al. · 2021

The ability to culture and differentiate neural stem cells (NSCs) to generate functional neural populations is attracting increasing attention due to its potential to enable cell-therapies to treat neurodegenerative diseases. Recent studie…

The effect of electrospun scaffolds on the glycosaminoglycan profile of differentiating neural stem cells Open

Fábio F. F. Garrudo, Paiyz E. Mikael, Ke Xia, João C. Silva, Yilan Ouyang , et al. · 2021

Kartogenin-loaded coaxial PGS/PCL aligned nanofibers for cartilage tissue engineering Open

João C. Silva, Ranodhi N. Udangawa, Jianle Chen, Chiara Mancinelli, Fábio F. F. Garrudo , et al. · 2019

Polybenzimidazole nanofibers for neural stem cell culture Open

Fábio F. F. Garrudo, Ranodhi N. Udangawa, Pauline R. Hoffman, Laura Sordini, Caitlyn A. Chapman , et al. · 2019

Polyaniline-polycaprolactone blended nanofibers for neural cell culture Open

Fábio F. F. Garrudo, Caitlyn A. Chapman, Pauline R. Hoffman, Ranodhi N. Udangawa, João C. Silva , et al. · 2019

Magnetized fibers for the cancer therapy Open

Fábio F. F. Garrudo · 2016

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