Fabio Magliulo
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View article: Management of Transcatheter Aortic Valve Implantation and Complex Aorta Anatomy: The Importance of Pre-Procedural Planning
Management of Transcatheter Aortic Valve Implantation and Complex Aorta Anatomy: The Importance of Pre-Procedural Planning Open
Aortic stenosis is the most common primary valve lesion requiring surgery or, especially for older patients, transcatheter intervention (TAVI). We showcase a successful transfemoral TAVI procedure in a very high-risk patient and an extreme…
View article: Functionally Complete Coronary Revascularisation in Patients Presenting with ST-elevation MI and Multivessel Coronary Artery Disease
Functionally Complete Coronary Revascularisation in Patients Presenting with ST-elevation MI and Multivessel Coronary Artery Disease Open
Up to half of patients undergoing primary percutaneous coronary intervention of a culprit stenosis in the context of the ST-elevation MI may present with multivessel disease. The presence of non-culprit stenoses have been shown to affect t…
View article: Prognostic Implications of Declining Hemoglobin Content in Patients Hospitalized With Acute Coronary Syndromes
Prognostic Implications of Declining Hemoglobin Content in Patients Hospitalized With Acute Coronary Syndromes Open
View article: Population Trends in Rates of Percutaneous Coronary Revascularization for Acute Coronary Syndromes Associated With the COVID-19 Outbreak
Population Trends in Rates of Percutaneous Coronary Revascularization for Acute Coronary Syndromes Associated With the COVID-19 Outbreak Open
◼ percutaneous coronary interventionA reduction in hospital admissions for acute coronary syndromes (ACS) has been observed globally in the aftermath of the pneumonia outbreak caused by coronavirus disease 2019 (COVID-19). 1 Despite the em…
View article: P753 Impact of transcatheter aortic valve implantation on concomitant mitral regurgitation in patients with severe aortic stenosis
P753 Impact of transcatheter aortic valve implantation on concomitant mitral regurgitation in patients with severe aortic stenosis Open
Background Severe aortic stenosis (AS) and functional mitral regurgitation (MR) frequently coexist. There is no consensus about the optimal therapeutic strategy for patients with combined valve disease. Evidence has shown that double valve…
View article: One-Year Clinical Outcomes of the Legflow Drug-Coated Balloon for the Treatment of Femoropopliteal Occlusions Registry
One-Year Clinical Outcomes of the Legflow Drug-Coated Balloon for the Treatment of Femoropopliteal Occlusions Registry Open
Purpose: To report the 1-year outcomes of the prospective Legflow drug-coated balloon (DCB) registry, which evaluated the safety and 12-month efficacy of the Legflow balloon in the treatment of femoropopliteal disease. Methods: The Legflow…
View article: P6358Comparison of residual added index with residual sYNTAX score in the risk stratification of patients with incomplete coronary percutaneous revascularization after ST-elevation myocardial infarction
P6358Comparison of residual added index with residual sYNTAX score in the risk stratification of patients with incomplete coronary percutaneous revascularization after ST-elevation myocardial infarction Open
View article: Correction: Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis
Correction: Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis Open
[This corrects the article DOI: 10.1371/journal.pone.0154076.].
View article: Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis
Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis Open
[This corrects the article DOI: 10.1371/journal.pone.0154076.].
View article: Total occlusion of the abdominal aorta in a patient with renal failure and refractory hypertension: a case report
Total occlusion of the abdominal aorta in a patient with renal failure and refractory hypertension: a case report Open
Total occlusion of the abdominal aorta is unusual, and potentially catastrophic. It occurs in patients with advanced atherosclerotic occlusive disease, and can cause severe ischemic manifestations, depending on the site of obstruction. Pro…
View article: Endovascular treatment of carotid artery stenosis: evidences from randomized controlled trials and actual indications
Endovascular treatment of carotid artery stenosis: evidences from randomized controlled trials and actual indications Open
Atherosclerotic stenosis of common and internal carotid arteries is a well-recognized risk factor for ischemic stroke, and revascularization has been proven to be the main tool of prevention, particularly for patients with stenosis- relate…
View article: Recruitment of KDM2A and anti-dimethyl-H3K36 (H3K36me2) at Atp2a2 and Myh7 gene promoter regions in TAC hearts.
Recruitment of KDM2A and anti-dimethyl-H3K36 (H3K36me2) at Atp2a2 and Myh7 gene promoter regions in TAC hearts. Open
ChIP experiments were performed using antibodies indicated in each panel: A KDM2A; B–C anti-dimethyl-H3K36 (H3K36me2). Each experiment was repeated at least three times, and the quantitative PCR analyses were performed in tri…
View article: Atp2a2 and Myh7 promoter modifications in pressure overload-induced heart failure.
Atp2a2 and Myh7 promoter modifications in pressure overload-induced heart failure. Open
ChIP experiments were performed using antibodies indicated in each panel: A,C anti-DNMT1; B,D anti-DNMT3b; E–F anti-MeCp2. Each experiment was repeated at least three times, and the quantitative PCR analyses were perfo…
View article: The Murine Model of Mucopolysaccharidosis IIIB Develops Cardiopathies over Time Leading to Heart Failure
The Murine Model of Mucopolysaccharidosis IIIB Develops Cardiopathies over Time Leading to Heart Failure Open
Mucopolysaccharidosis (MPS) IIIB is a lysosomal disease due to the deficiency of the enzyme α-N-acetylglucosaminidase (NAGLU) required for heparan sulfate (HS) degradation. The disease is characterized by mild somatic features and severe n…
View article: Dermcidin: a skeletal muscle myokine modulating cardiomyocyte survival and infarct size after coronary artery ligation
Dermcidin: a skeletal muscle myokine modulating cardiomyocyte survival and infarct size after coronary artery ligation Open
Our data demonstrate that chronic limb ischaemia activates detrimental pathways in the ischaemic heart through humoral mechanisms of remote organ crosstalk. Thus, DCD may represent a novel important myokine modulating cardiomyocyte surviva…
View article: Novel Molecular Approaches in Heart Failure: Seven Trans-Membrane Receptors Signaling in the Heart and Circulating Blood Leukocytes
Novel Molecular Approaches in Heart Failure: Seven Trans-Membrane Receptors Signaling in the Heart and Circulating Blood Leukocytes Open
Heart failure (HF) is the result of molecular, cellular, and structural changes induced by cardiac load or injury. A complex network of signaling pathways have been involved in the development and progression of cardiac dysfunction. In thi…
View article: Primary Percutaneous Coronary Intervention in a Patient with Acute Inferior Myocardial Infarction and Agenesis of Right Coronary Artery. "In Search of a Coronary Ostium"
Primary Percutaneous Coronary Intervention in a Patient with Acute Inferior Myocardial Infarction and Agenesis of Right Coronary Artery. "In Search of a Coronary Ostium" Open