Fabio Valeri
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View article: The Effect of Posture on Retinal Venous Pressure
The Effect of Posture on Retinal Venous Pressure Open
This study aimed to investigate the impact of posture on retinal venous pressure (RVP) in a diverse cohort. The research delves into determining the percentage distribution of normal and increased RVP among healthy volunteers across variou…
View article: Flammer Syndrome in Aesthetic Medicine: The Importance of Recognizing Signs and Symptoms
Flammer Syndrome in Aesthetic Medicine: The Importance of Recognizing Signs and Symptoms Open
Purpose
\nFlammer syndrome (FS), a clinical entity characterized by primary vascular dysregulation of blood flow together with various signs and symptoms, has been reported in both healthy individuals and those with certain diseases. Adequ…
View article: Optimising prescribing in older adults with multimorbidity and polypharmacy in primary care (OPTICA): cluster randomised clinical trial
Optimising prescribing in older adults with multimorbidity and polypharmacy in primary care (OPTICA): cluster randomised clinical trial Open
Objective To study the effects of a primary care medication review intervention centred around an electronic clinical decision support system (eCDSS) on appropriateness of medication and the number of prescribing omissions in older adults …
View article: Optimizing Prescribing in Older Adults with Multimorbidity and Polypharmacy in Primary Care: A Cluster Randomized Clinical Trial (OPTICA Trial)
Optimizing Prescribing in Older Adults with Multimorbidity and Polypharmacy in Primary Care: A Cluster Randomized Clinical Trial (OPTICA Trial) Open
Importance Inappropriate prescribing and prescribing omissions are major drivers of healthcare-related harm. Medication review may help improve pharmacotherapy. Objective To study the effects of a primary care medication review interventio…
View article: The Effect of Paraspinal Fatty Muscle Infiltration and Cumulative Lumbar Spine Degeneration on the Outcome of Patients With Lumbar Spinal Canal Stenosis: Analysis of the Lumbar Stenosis Outcome Study (LSOS) Data
The Effect of Paraspinal Fatty Muscle Infiltration and Cumulative Lumbar Spine Degeneration on the Outcome of Patients With Lumbar Spinal Canal Stenosis: Analysis of the Lumbar Stenosis Outcome Study (LSOS) Data Open
Study Design. Prospective. Objective. To investigate the influence of paraspinal fatty muscle infiltration (FMI) and cumulative lumbar spine degeneration as assessed by magnetic resonance imaging on long-term clinical outcome measures in p…
View article: Advance care planning for the severely ill in the hospital: a randomized trial
Advance care planning for the severely ill in the hospital: a randomized trial Open
Objectives To investigate the impact of advance care planning (ACP) including decision aids for severely ill medical inpatients. Methods Single-centre randomised controlled trial at a Swiss university hospital. Patients were randomly assig…
View article: Incidence of Revision Surgery After Decompression With vs Without Fusion Among Patients With Degenerative Lumbar Spinal Stenosis
Incidence of Revision Surgery After Decompression With vs Without Fusion Among Patients With Degenerative Lumbar Spinal Stenosis Open
This cohort study showed no significant association between the type of index operation for DLSS-decompression alone or fusion-and the need for revision surgery or the outcomes of pain, disability, and quality of life among patients after …
View article: Correction: Russians are the fastest 100-km ultra-marathoners in the world
Correction: Russians are the fastest 100-km ultra-marathoners in the world Open
[This corrects the article DOI: 10.1371/journal.pone.0199701.].
View article: The Effect of Magnesium on Retinal Venous Pressure of Patients with Normal-Tension Glaucoma and Flammer Syndrome
The Effect of Magnesium on Retinal Venous Pressure of Patients with Normal-Tension Glaucoma and Flammer Syndrome Open
Purpose: To measure the retinal venous pressure (RVP) in both eyes of patients with normal-tension glaucoma (NTG) and Flammer Syndrome before and 6 weeks after treatment with magnesium.
\nMethods: This retrospective study included 30 patie…
View article: Long-Term Effects of Financial Incentives for General Practitioners on Quality Indicators in the Treatment of Patients With Diabetes Mellitus in Primary Care—A Follow-Up Analysis of a Cluster Randomized Parallel Controlled Trial
Long-Term Effects of Financial Incentives for General Practitioners on Quality Indicators in the Treatment of Patients With Diabetes Mellitus in Primary Care—A Follow-Up Analysis of a Cluster Randomized Parallel Controlled Trial Open
Background: The effect of financial incentives on the quality of primary care is of high interest, and so is its sustainability after financial incentives are withdrawn. Objective: To assess both long-term effects and sustainability of fin…
View article: Physician-dispensing as a determinant of clinical and process measurements in patients at increased cardiovascular risk: A cross-sectional study in Swiss general practice
Physician-dispensing as a determinant of clinical and process measurements in patients at increased cardiovascular risk: A cross-sectional study in Swiss general practice Open
We found no relevant differences in selected clinical measurements between physician- and pharmacist-dispensing, and mixed results in process measurements. Our results do not indicate that one drug-dispensing channel is superior to the oth…
View article: Sample size calculation using Markov chains for a one-arm study of heroin administration routes
Sample size calculation using Markov chains for a one-arm study of heroin administration routes Open
Sample size calculations for trials with time-to-event outcomes are usually based on the assumption that an event – prototypically death in survival analysis – occurs only once per sample unit. However, events like changes in disease statu…
View article: Effects of a DRG-based hospital reimbursement on the health care utilization and costs in Swiss primary care: A retrospective “quasi-experimental” analysis
Effects of a DRG-based hospital reimbursement on the health care utilization and costs in Swiss primary care: A retrospective “quasi-experimental” analysis Open
This study found no evidence of any effect of the introduction of the SwissDRG on the yearly trend of primary care consultations and costs. Nevertheless, potential negative impacts on vulnerable patients, as chronically ill patients, could…
View article: Point-of-Care C-Reactive Protein Testing to Reduce Antibiotic Prescribing for Respiratory Tract Infections in Primary Care: Systematic Review and Meta-Analysis of Randomised Controlled Trials
Point-of-Care C-Reactive Protein Testing to Reduce Antibiotic Prescribing for Respiratory Tract Infections in Primary Care: Systematic Review and Meta-Analysis of Randomised Controlled Trials Open
C-reactive protein (CRP) point-of-care testing (POCT) is increasingly being promoted to reduce diagnostic uncertainty and enhance antibiotic stewardship. In primary care, respiratory tract infections (RTIs) are the most common reason for i…
View article: MEMSID: Results From a Phase 2 Pilot Study on Memantine Treatment for Sickle Cell Disease
MEMSID: Results From a Phase 2 Pilot Study on Memantine Treatment for Sickle Cell Disease Open
Supplemental Digital Content is available in the text
View article: Quality performance and associated factors in Swiss diabetes care – A cross-sectional study
Quality performance and associated factors in Swiss diabetes care – A cross-sectional study Open
The influence of practice, general practitioner and patient characteristics on quality indicator performance was surprisingly small and room for improvement in quality indicator performance of Swiss general practitioners seems to exist in …
View article: Identification scheme for comorbidities and co-medication.
Identification scheme for comorbidities and co-medication. Open
BMI = Body mass index, ICPC = International classification of primary care, ATC = anatomical therapeutic chemical code, LDL = low density lipoprotein, HDL = High density lipoprotein, GFR = glomerular filtration rate. (DOCX)
View article: Gout management in Swiss primary care – a retrospective observational study
Gout management in Swiss primary care – a retrospective observational study Open
BACKGROUND Gout is the most common form of inflammatory arthritis worldwide and its prevalence is rising. In Switzerland, there are no data available on the characteristics and treatment of gout patients. In this study, we aimed to describ…
View article: Additional file 6 of Effect of a patient-centred deprescribing procedure in older multimorbid patients in Swiss primary care - A cluster-randomised clinical trial
Additional file 6 of Effect of a patient-centred deprescribing procedure in older multimorbid patients in Swiss primary care - A cluster-randomised clinical trial Open
Additional file 6. Anonymised data set. A minimal anonymised data set, necessary to replicate our study findings. An additional data description is included.
View article: Time trends in prostate cancer screening in Swiss primary care (2010 to 2017) – A retrospective study
Time trends in prostate cancer screening in Swiss primary care (2010 to 2017) – A retrospective study Open
Swiss general practitioners adapted screening behavior as early as evidence of a limited health benefit evolved, while using a risk-adapted approach whenever performing multiple testing. Updated recommendations might have helped to maintai…
View article: Referring Physicians Assess the Quality of Outpatient Diagnostic Imaging Services: Development and Psychometric Evaluation of a Questionnaire
Referring Physicians Assess the Quality of Outpatient Diagnostic Imaging Services: Development and Psychometric Evaluation of a Questionnaire Open
Goal In order to ensure high-quality cooperation between referring physicians and imaging services, it is important to assess the quality of imaging services as perceived by referring physicians. The present study aimed to develop and vali…
View article: Advance care planning for the severely ill in the hospital: a randomized trial
Advance care planning for the severely ill in the hospital: a randomized trial Open
Objectives To investigate the impact of advance care planning (ACP) including decision aids for severely ill medical inpatients. Methods Single-centre randomised controlled trial at a Swiss university hospital. Patients were randomly assig…
Sex difference in open-water swimming—The Triple Crown of Open Water Swimming 1875-2017 Open
The aim of the present study was to compare swimming performances of successful finishers of the 'Triple Crown of Open Water Swimming' from 1875 to 2017, assessing the effects of sex, the place of event and the nationality of swimmers. Dat…
View article: Russians are the fastest 100-km ultra-marathoners in the world
Russians are the fastest 100-km ultra-marathoners in the world Open
In contrast to existing findings investigating the top 10 by nationality, this analysis showed that ultra-marathoners from Russia, not Japan, were the fastest 100-km ultra-marathoners worldwide when considering all races held since 1959.