Explanipedia

Data from Sleep Patterns and Risk of Prostate Cancer: A Population-Based Case Control Study in France (EPICAP) Open

Emilie Cordina‐Duverger, Sylvie Cénée, Brigitte Trétarre, Xavier Rebillard, Pierre‐Jean Lamy , et al. · 2025

Background:Sleep disturbances have been singled out for their implication in the risk of several cancer sites. However, results for prostate cancer are still inconsistent.Methods:We used data from the EPICAP study, a French population-base…

8265508 Serum organochlorine insecticide concentrations and risk of aggressive prostate cancer Open

Deborah A. Tadesse, Lauren M. Hurwitz, Richard Biritwum, Yao Tettey, Andrew A. Adjei , et al. · 2025

Firefighting, other protective service occupations and prostate cancer risk: a pooled analysis of three case-control studies Open

Wendy Bijoux, Marie Parent, Hugues Richard, Gemma Castaño-Vinyals, Marina Pollán , et al. · 2025

Background: Prostate cancer (PCa) is the most frequent incident cancer among males in industrialized countries, but little is known about its aetiology. A role for occupational exposures is suggested. Occupational exposure as a fir…

Kidney and gallbladder stones and the risk of prostate cancer: Results from the EPICAP study Open

Melissa Sawaya, Emilie Cordina‐Duverger, Pierre‐Jean Lamy, Brigitte Trétarre, F. Ménégaux · 2025

Background Prostate cancer remains the most frequent cancer among men, representing a significant health burden. Despite its high morbidity and mortality rates, the etiology of prostate cancer remains relatively unknown, with only non-modi…

Day care, childhood infections, and risk of neuroblastoma Open

F. Ménégaux, Andrew F. Olshan, Joseph P. Neglia, Bradley H Pollock, Melissa L. Bondy · 2024

Neuroblastoma is the most common cancer in infants worldwide, but little is known about its etiology. Infectious etiologies involving the immune system have been hypothesized for some childhood cancers, especially leukemia, but the role of…

Sexually and non‐sexually transmitted infections and the risk of prostate cancer: Results from the EPICAP study Open

Melissa Sawaya, Emilie Cordina‐Duverger, Pierre‐Jean Lamy, Xavier Rébillard, Brigitte Trétarre , et al. · 2024

Introduction Prostate cancer (PCa) is by far the most common type of cancer among men in western countries. However, relatively little is known about its etiology despite the high morbidity and mortality. It has been suggested that chronic…

Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study Open

Eleanor L. Watts, Tomas I. Gonzales, Tessa Strain, Pedro F. Saint‐Maurice, D. Timothy Bishop , et al. · 2023

Sexually and Non-sexually Transmitted Infections and The risk of Prostate Cancer Open

Manabu Sawaya, Emilie Cordina‐Duverger, Pierre‐Jean Lamy, Xavier Rébillard, Brigitte Trétarre , et al. · 2023

Introduction Prostate cancer (PCa) is by far the most common type of cancer among men in western countries. However, relatively little is known about its etiology despite the high morbidity and mortality rates, where only advanced age, eth…

Management of adhesive small bowel obstruction: the results of a large retrospective study Open

Elisa Maienza, G. Godiris-Petit, S. Noullet, F. Ménégaux, Nathalie Chéreau · 2023

Background Postoperative adhesive small bowel obstruction (SBO) is a frequent cause of hospital admission in a surgical department. Emergency surgery is needed in a majority of patients with bowel ischemia or peritonitis; most adhesive SBO…

African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer Open

Roshan Karunamuni, Minh‐Phuong Huynh‐Le, Chun Chieh Fan, Wesley K. Thompson, Rosalind A. Eeles , et al. · 2023

Polygenic hazard score (PHS) models are associated with age at diagnosis of prostate cancer. Our model developed in Europeans (PHS46) showed reduced performance in men with African genetic ancestry. We used a cross-validated search to iden…

A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry Open

B.F. Darst, Raymond W. Hughley, Andrea Pfennig, Ujani Hazra, Chun Chieh Fan , et al. · 2023

Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24 Open

Roshan Karunamuni, Minh‐Phuong Huynh‐Le, Chun Chieh Fan, Wesley K. Thompson, Arthur Lui , et al. · 2023

A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry Open

B.F. Darst, P. Wan, X. Sheng, Jeannette T. Bensen, S.A. Ingles , et al. · 2023

Germline variation at 8q24 and prostate cancer risk in men of European ancestry Open

Marco Matejcic, Edward J. Saunders, Tokhir Dadaev, Mark N. Brook, Kan Wang , et al. · 2023

Chromosome 8q24 is a susceptibility locus for multiple cancers, including prostate cancer. Here we combine genetic data across the 8q24 susceptibility region from 71,535 prostate cancer cases and 52,935 controls of European ancestry to def…

Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry Open

Burcu F. Darst, Jiayi Shen, Ravi Madduri, Alexis Rodriguez, Yukai Xiao , et al. · 2023

Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry Open

Burcu F. Darst, Jiayi Shen, Ravi Madduri, Alexis Rodriguez, Yukai Xiao , et al. · 2023

Genome-wide polygenic risk scores (GW-PRS) have been reported to have better predictive ability than PRS based on genome-wide significance thresholds across numerous traits. We compared the predictive ability of several GW-PRS approaches t…

A-287 UTILITY OF CORRELATION BETWEEN TI-RADS AND BETHESDA CLASSIFICATION TO ESTIMATE RISK OF MALIGNANCY FOR CYTOLOGICALLY INDETERMINATE THYROID NODULES Open

Nathalie Chéreau, F. Ménégaux, J-B Bertin · 2023

Background Currently, we are directing therapeutic strategy based on the results of fine-needle aspiration biopsy defined by the Bethesda classification. The TI-RADS classification of ultrasound features can help surgeons to estimate the r…

Sexually and non-sexually transmitted infections and the risk of Prostate Cancer: results from the EPICAP study Open

Melissa Sawaya, Emilie Cordivadverger, Pierre‐Jean Lamy, Xavier Rébillard, Brigitte Trétarre , et al. · 2023

Population Medicine considers the following types of articles:• Research Papers -reports of data from original research or secondary dataset analyses.• Review Papers -comprehensive, authoritative, reviews within the journal's scope.These i…

Data from 19p13.1 Is a Triple-Negative–Specific Breast Cancer Susceptibility Locus Open

Kristen N. Stevens, Zachary Fredericksen, Celine M. Vachon, Xianshu Wang, Sara Margolin , et al. · 2023

The 19p13.1 breast cancer susceptibility locus is a modifier of breast cancer risk in BRCA1 mutation carriers and is also associated with the risk of ovarian cancer. Here, we investigated 19p13.1 variation and risk of breast cancer …

Supplementary Tables 1-13 from 19p13.1 Is a Triple-Negative–Specific Breast Cancer Susceptibility Locus Open

Kristen N. Stevens, Zachary Fredericksen, Celine M. Vachon, Xianshu Wang, Sara Margolin , et al. · 2023

PDF file - 272K

Supplementary Tables 1-13 from 19p13.1 Is a Triple-Negative–Specific Breast Cancer Susceptibility Locus Open

Kristen N. Stevens, Zachary Fredericksen, Celine M. Vachon, Xianshu Wang, Sara Margolin , et al. · 2023

PDF file - 272K

Data from 19p13.1 Is a Triple-Negative–Specific Breast Cancer Susceptibility Locus Open

Kristen N. Stevens, Zachary Fredericksen, Celine M. Vachon, Xianshu Wang, Sara Margolin , et al. · 2023

The 19p13.1 breast cancer susceptibility locus is a modifier of breast cancer risk in BRCA1 mutation carriers and is also associated with the risk of ovarian cancer. Here, we investigated 19p13.1 variation and risk of breast cancer …

Occupational heat exposure and prostate cancer risk: A pooled analysis of case-control studies Open

Alice Hinchliffe, Juan Alguacil, Wendy Bijoux, Manolis Kogevinas, F. Ménégaux , et al. · 2022

Findings from this study provide no clear evidence for an association between occupational heat exposure and prostate cancer risk.

Occupational heat exposure and prostate cancer risk: a pooled analysis of case-control studies Open

Alice Hinchliffe, Juan Alguacil, Wendy Bijoux, Manolis Kogevinas, F. Ménégaux , et al. · 2022

Background and aim: Heat exposures occur frequently in many indoor and outdoor occupations. In our previous work, we observed some evidence for a positive association of occupational heat exposure and breast cancer risk. Here we seek to ex…

Pre-diagnostic C-reactive protein concentrations, CRP genetic variation and mortality among individuals with colorectal cancer in Western European populations Open

Katharina Nimptsch, Krasimira Aleksandrova, Veronika Fedirko, Mazda Jenab, Marc J. Gunter , et al. · 2022

Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score Open

Minh‐Phuong Huynh‐Le, Roshan Karunamuni, Chun Chieh Fan, Asona Lui, Wesley K. Thompson , et al. · 2022

Occupation and prostate Cancer risk: results from the epidemiological study of prostate cancer (EPICAP) Open

Wendy Bijoux, Emilie Cordina‐Duverger, Soumaya Balbolia, Pierre‐Jean Lamy, Xavier Rébillard , et al. · 2022

A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry Open

Burcu F. Darst, Raymond W. Hughley, Aaron Pfennig, Ujani Hazra, C.P.S. Fan , et al. · 2022

Additional file 1 of Occupation and prostate Cancer risk: results from the epidemiological study of prostate cancer (EPICAP) Open

Wendy Bijoux, Emilie Cordina‐Duverger, Soumaya Balbolia, Pierre‐Jean Lamy, Xavier Rébillard , et al. · 2022

Additional file 1. The results for associations between all occupations (1 to 3-digits with at least 10 subjects) and PCa can be found in a supplementary document named: Additional file 1 - Occupation and Prostate Cancer risk - results fro…

P-220 Assessing prostate cancer risk among protective service workers and health professionals Open

Wendy Bijoux, Marie‐Élise Parent, Manolis Kogevinas, Hugues Richard, F. Ménégaux , et al. · 2021

Introduction Fire-fighting occupations and nightshift work are possibly/probably carcinogenic to humans (Groups 2A/2B), according to IARC. Some recent studies also found a higher risk for prostate cancer (PCa) for these occupational catego…

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