Fadoua Montassar
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View article: Lebecetin, a C‐type lectin, inhibits choroidal and retinal neovascularization
Lebecetin, a C‐type lectin, inhibits choroidal and retinal neovascularization Open
Angiogenesis is a cause of visual impairment and blindness in the wet form of age‐related macular degeneration and in ischemic retinopathies. Current therapies include use of anti‐VEGF agents to reduce choroidal neovascularization (CNV) an…
View article: Upregulation of P2RX7 in<i>Cx3cr1</i>-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration
Upregulation of P2RX7 in<i>Cx3cr1</i>-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration Open
Photoreceptor degeneration in age-related macular degeneration (AMD) is associated with an infiltration and chronic accumulation of mononuclear phagocytes (MPs). We have previously shown that Cx3cr1 -deficient mice develop age- and stress-…