Faezahtul Arbaeyah Hussain
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View article: Automated quantification and feature extraction of nuclei in diffuse large B-cell lymphoma using advanced imaging techniques
Automated quantification and feature extraction of nuclei in diffuse large B-cell lymphoma using advanced imaging techniques Open
Diffuse Large B-Cell Lymphoma is a subtype of non-Hodgkin lymphoma that occurs worldwide; around 80 thousand new cases were recorded in 2022. The accurate diagnosis and subtyping of non-Hodgkin lymphoma pose significant challenges that nec…
View article: Enhanced HoVerNet Optimization for Precise Nuclei Segmentation in Diffuse Large B-Cell Lymphoma
Enhanced HoVerNet Optimization for Precise Nuclei Segmentation in Diffuse Large B-Cell Lymphoma Open
Background/Objectives: Diffuse Large B-Cell Lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma and demands precise segmentation and classification of nuclei for effective diagnosis and disease severity assessment. This stu…
View article: Acute abdomen with perforated viscus: A case of intestinal T-cell lymphoma, not otherwise specified
Acute abdomen with perforated viscus: A case of intestinal T-cell lymphoma, not otherwise specified Open
Small bowel lymphoma is a rare disease with nonspecific presentation. Intestinal T-cell lymphoma, not otherwise specified, is an aggressive lymphoma type with a poor prognosis and may be widespread upon presentation. We report a case of a …
View article: The Current Challenges Review of Deep Learning-Based Nuclei Segmentation of Diffuse Large B-Cell Lymphoma
The Current Challenges Review of Deep Learning-Based Nuclei Segmentation of Diffuse Large B-Cell Lymphoma Open
View article: Secondary Acute Myeloid Leukemia in Treatment‐Naïve Primary Testicular Diffuse Large B‐Cell Lymphoma
Secondary Acute Myeloid Leukemia in Treatment‐Naïve Primary Testicular Diffuse Large B‐Cell Lymphoma Open
Secondary acute myeloid leukemia (sAML) typically arises from a prior myeloid malignancy or as a complication of cytotoxic therapy for other cancers. Rarely, it may develop without antecedent treatment, particularly in lymphoid malignancie…
View article: Chronic mastitis manifest as complex breast cyst in ultrasound and the role of elastography: A case series
Chronic mastitis manifest as complex breast cyst in ultrasound and the role of elastography: A case series Open
This case series aims to describe the clinical presentation of mastitis, the conventional sonography and elastography findings, and histopathological features in the diagnosis of chronic mastitis. We present 3 cases of breast swelling in y…
View article: Primary Cold Agglutinin Disease Associated B Lymphoproliferative Neoplasm – A Case Report
Primary Cold Agglutinin Disease Associated B Lymphoproliferative Neoplasm – A Case Report Open
Cold autoimmune hemolytic anaemia (AIHA) has several causes, including Primary Cold Agglutinin (CAD). The cold AIHA in CAD is due to autoantibody anti-I. Most antibodies in cold AIHA are IgM subtype that optimally binds to red blood cells …
View article: Phaehyphomycosis or Eumycetoma: A Case Report of a Diagnostic Dilemma
Phaehyphomycosis or Eumycetoma: A Case Report of a Diagnostic Dilemma Open
We reported a case of recurrent subcutaneous swelling on the left foot of a diabetic patient. Two different organisms, Cladosporium spp. and Phaeoacremonium krajdenii were isolated, both of which are associated with phaeohyphomycosis and e…
View article: Successful Treatment of Extraosseous Plasmacytoma of the Oropharynx with Cervical Lymph Node Involvement
Successful Treatment of Extraosseous Plasmacytoma of the Oropharynx with Cervical Lymph Node Involvement Open
View article: Worldwide Prevalence of Epstein–Barr Virus in Patients with Burkitt Lymphoma: A Systematic Review and Meta-Analysis
Worldwide Prevalence of Epstein–Barr Virus in Patients with Burkitt Lymphoma: A Systematic Review and Meta-Analysis Open
Burkitt lymphoma (BL) is a form of B-cell malignancy that progresses aggressively and is most often seen in children. While Epstein–Barr virus (EBV) is a double-stranded DNA virus that has been linked to a variety of cancers, it can transf…
View article: Evaluation of Signal Transducer and Activator of Transcription 3 (STAT-3) Protein Expression in Non-Hodgkin Lymphoma Cases in Hospital USM
Evaluation of Signal Transducer and Activator of Transcription 3 (STAT-3) Protein Expression in Non-Hodgkin Lymphoma Cases in Hospital USM Open
Background: Evolving targeted therapy on Janus Associated Kinase-Signal Transducer and Activator of Transcription (JAK-STAT) signaling pathway, especially pertaining to STAT-3 protein in non-Hodgkin lymphoma (NHL), provides new treatment s…
View article: Epstein-Barr Virus-Negative Associated with Sinonasal Lymphoepithelial Carcinoma –A Rare Case Report
Epstein-Barr Virus-Negative Associated with Sinonasal Lymphoepithelial Carcinoma –A Rare Case Report Open
Lymphoepithelial carcinoma (LEC), also known as lymphoepithelioma-like carcinoma, is a rare type of cancer. LEC can affect any organ, but it is most common in the head and neck region. Sinonasal lymphoepithelial carcinoma (SNLEC) is an exa…
View article: Malignant Dural Solitary Fibrous Tumor; An Exceedingly Rare Entity
Malignant Dural Solitary Fibrous Tumor; An Exceedingly Rare Entity Open
Introduction/Objective A solitary fibrous tumor (SFT) is an extremely rare mesenchymal neoplasm, accounting for <1% of all primary CNS tumors. Most SFT is dural-based and occurs predominantly in the fourth to sixth decade of life. Here,…
View article: The relationship between crying of premature infants with Monro-kellie hypothesis and increase of ventricular CSF Based on Doppler ultrasound findings
The relationship between crying of premature infants with Monro-kellie hypothesis and increase of ventricular CSF Based on Doppler ultrasound findings Open
Introduction: Infant crying causes an increase in intracranial pressure which is equivalent to a decrease in CSF and also a decrease in CSF before ischemic and hemorrhagic strokes observed. The object of this study is to evaluate the effec…
View article: Application of Baculovirus Expression Vector system (BEV) for COVID-19 diagnostics and therapeutics: a review
Application of Baculovirus Expression Vector system (BEV) for COVID-19 diagnostics and therapeutics: a review Open
View article: The Role of NOTCH1, GATA3, and c-MYC in T Cell Non-Hodgkin Lymphomas
The Role of NOTCH1, GATA3, and c-MYC in T Cell Non-Hodgkin Lymphomas Open
Lymphomas are heterogeneous malignant tumours of white blood cells characterised by the aberrant proliferation of mature lymphoid cells or their precursors. Lymphomas are classified into main types depending on the histopathologic evidence…
View article: Corrigendum to “Master of mimicry: Rare primary cutaneous anaplastic large cell lymphoma presenting as fungating parotid tumor–case report and review” [Int. J. Surg. Case Rep. 94 (MAY 2022) 1–5, IJSCR_107135]
Corrigendum to “Master of mimicry: Rare primary cutaneous anaplastic large cell lymphoma presenting as fungating parotid tumor–case report and review” [Int. J. Surg. Case Rep. 94 (MAY 2022) 1–5, IJSCR_107135] Open
View article: Advanced Nasopharyngeal Carcinoma with Generalized Lymphadenopathy Masquerade as Lymphoma.
Advanced Nasopharyngeal Carcinoma with Generalized Lymphadenopathy Masquerade as Lymphoma. Open
NPC may share clinical features with other sinonasal pathologies or other malignant lymphoproliferative disorders that lead to a delay in diagnosis. NPC should be one of the differential diagnoses for any cases presenting with cervical lym…
View article: Master of mimicry: Rare primary cutaneous anaplastic large cell lymphoma presenting as fungating parotid tumor–case report and review
Master of mimicry: Rare primary cutaneous anaplastic large cell lymphoma presenting as fungating parotid tumor–case report and review Open
PC-ALCL is a master of mimicry. To prevent serious morbidity, awareness regarding this entity as a differential diagnosis compared to the common malignant parotid tumors need to be raised.
View article: Submandibular Gland Basal Cell Adenoma.
Submandibular Gland Basal Cell Adenoma. Open
BCA can be accurately diagnosed only through histological observations due to its resemblance to various benign and malignant salivary and non-salivary gland tumours, which are difficult to biopsy.
View article: A Malignant Lymphoma Presenting as a Non-healing Oral Ulcer
A Malignant Lymphoma Presenting as a Non-healing Oral Ulcer Open
Lymphomas are the second most common non-epithelial malignant tumour in the oral and maxillofacial region. Non-Hodgkin lymphoma (NHL) is more frequently diagnosed eventhough oral cavity involvement is less than 4% of all NHLs. Usually, the…
View article: Haemophagocytic Lymphohistiocytosis in a Malay infant: Rare, Old and Often Forgotten Disease
Haemophagocytic Lymphohistiocytosis in a Malay infant: Rare, Old and Often Forgotten Disease Open
Haemophagocytic lymphohistiocytosis (HLH) is a rare disease but potentially life threatening clinical syndrome. It is caused by a multisystemic hyperinflammatory process secondary to severe hypercytokinemia with excessive and uncontrolled …
View article: Kimura Disease as a Rare Cause of Proptosis: A Case Report
Kimura Disease as a Rare Cause of Proptosis: A Case Report Open
Kimura disease (KD) is a rare chronic inflammatory disorder of unknown aetiology that primarily affects the head and neck region with lymph node involvement. Young to middle-aged adult Asian males are predominantly affected. The most commo…
View article: EVALUATION OF PROGRAM DEATH 1 (PD-1) AND PD-1 LIGAND (PD-L1) EXPRESSIONS IN HISTOLOGICAL SUBTYPES OF PRIMARY EXTRANODAL NON HODGKIN LYMPHOMA.
EVALUATION OF PROGRAM DEATH 1 (PD-1) AND PD-1 LIGAND (PD-L1) EXPRESSIONS IN HISTOLOGICAL SUBTYPES OF PRIMARY EXTRANODAL NON HODGKIN LYMPHOMA. Open
Programmed death 1 (PD-1) protein and its ligands, PD-L1 are two proteins that have been widely studied in many solid tumours. However, only limited observations were made in lymphomas, which were mainly Hodgkin lymphomas. We aimed to eval…
View article: Pediatric Sinonasal Rhabdomyosarcoma Presented as Squint: A Case Report and Literature Review
Pediatric Sinonasal Rhabdomyosarcoma Presented as Squint: A Case Report and Literature Review Open
Rhabdomyosarcoma (RMS) is the most common soft-tissue tumor in children, frequently affecting the nose, nasopharynx, and paranasal sinuses. RMS of this sinonasal region manifests with non-specific nasal symptoms of allergic rhinitis, sinus…
View article: Rhabdomyosarcoma in Ovary- Pathologist’s Diagnostic Dilemma
Rhabdomyosarcoma in Ovary- Pathologist’s Diagnostic Dilemma Open
Introduction/Objective Rhabdomyosarcoma is the most common pediatric soft tissue sarcoma. However, rhabdomyosarcoma in the ovary is exceptionally unusual and presents a diagnostic challenge. We report one such case and its clinical and pat…
View article: Placental Mesenchymal Dysplasia, An Exceedingly Rare Entity and Challenging Diagnosis
Placental Mesenchymal Dysplasia, An Exceedingly Rare Entity and Challenging Diagnosis Open
Introduction/Objective Placental mesenchymal dysplasia (PMD) is an extremely rare entity with an incidence of only 0.02/1000 deliveries. Methods/Case Report We present a case of a 26 year-old female Gravida 3, Para 1 with intrauterine preg…
View article: Duodenal Duplication Cyst in adult male; An Extremely Rare Entity and a Diagnostic Pitfall leading to Whipple procedure
Duodenal Duplication Cyst in adult male; An Extremely Rare Entity and a Diagnostic Pitfall leading to Whipple procedure Open
Introduction/Objective Whipple procedure is a complex, invasive operation and has high morbidity and mortality. It is the most commonly indicated treatment for treating malignant tumors, however, it can be also used for benign entities as …
View article: Aggressive primary sinonasal Ewing sarcoma with intraorbital and intracranial extension
Aggressive primary sinonasal Ewing sarcoma with intraorbital and intracranial extension Open
Ewing sarcoma (ES) of the extraskeletal form is a rare occurrence and even rarer to manifest in the sinonasal tract. We describe a case of an advanced sinonasal ES with orbital and intracranial extension that was managed with chemotherapy …
View article: Lignosus rhinocerotis Cooke Ryvarden ameliorates airway inflammation, mucus hypersecretion and airway hyperresponsiveness in a murine model of asthma
Lignosus rhinocerotis Cooke Ryvarden ameliorates airway inflammation, mucus hypersecretion and airway hyperresponsiveness in a murine model of asthma Open
Lignosus rhinocerotis Cooke. ( L . rhinocerotis ) is a medicinal mushroom traditionally used in the treatment of asthma and several other diseases by the indigenous communities in Malaysia. In this study, the effects of L . rhinocerotis on…