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View article: Curzerenone attenuates neuroinflammation and oxidative stress via MAPK signaling pathway modulation: Network pharmacology and in-vivo insights in a scopolamine-induced model of Alzheimer's disease
Curzerenone attenuates neuroinflammation and oxidative stress via MAPK signaling pathway modulation: Network pharmacology and in-vivo insights in a scopolamine-induced model of Alzheimer's disease Open
View article: Impact of pharmacist-led educational services in promoting breast cancer awareness
Impact of pharmacist-led educational services in promoting breast cancer awareness Open
Background Breast cancer is rapidly increasing worldwide. Pakistan has a high incidence rate of one in every nine women. The lack of awareness is the major reason for delayed diagnosis, thus resulting in high mortality. This study aimed to…
View article: Controlled Release Drug Delivery System Via Electrospraying and Electrospinning
Controlled Release Drug Delivery System Via Electrospraying and Electrospinning Open
View article: Combination Therapies and Multi-Drug Delivery Systems
Combination Therapies and Multi-Drug Delivery Systems Open
View article: Assessment of Anti-Oxidant and Hepatoprotective Potential of Euphorbia Milii against Carbon Tetrachloride Induced Hepatic Damage in Experimental Rats
Assessment of Anti-Oxidant and Hepatoprotective Potential of Euphorbia Milii against Carbon Tetrachloride Induced Hepatic Damage in Experimental Rats Open
The plant Euphorbia milii (E. milii) is used as a folk medicine for the treatment of hepatitis, warts and cancer. However, the anti-oxidant and hepatoprotective activities of E.milii remain largely unknown. The present study is aimed to ev…
View article: Development and evaluation of the rivaroxaban loaded nanostructured lipid carriers for improved oral bioavailability and safety
Development and evaluation of the rivaroxaban loaded nanostructured lipid carriers for improved oral bioavailability and safety Open
A recent surge in deep vein thrombosis (DVT) has urged researchers to find potential candidates and new ways of drug delivery to treat the condition. Rivaroxaban (RIVA) is one of the active pharmaceutical agents used to treat DVT due to it…
View article: Corrigendum to “Comparative analysis of novel modified drug delivery systems for improving the oral bioavailability of water-insoluble tadalafil using copovidone, TPGS and hydroxypropyl-β-cyclodextrin” [Biomed. Pharmacother. 186 (2025) 118039]
Corrigendum to “Comparative analysis of novel modified drug delivery systems for improving the oral bioavailability of water-insoluble tadalafil using copovidone, TPGS and hydroxypropyl-β-cyclodextrin” [Biomed. Pharmacother. 186 (2025) 118039] Open
View article: Comparative analysis of novel modified drug delivery systems for improving the oral bioavailability of water-insoluble tadalafil using copovidone, TPGS and hydroxypropyl-β-cyclodextrin
Comparative analysis of novel modified drug delivery systems for improving the oral bioavailability of water-insoluble tadalafil using copovidone, TPGS and hydroxypropyl-β-cyclodextrin Open
This study aims to develop novel modified drug delivery systems (MDDS) including solid dispersions, solid self-nanoemulsifying drug delivery system (S-SNEDDS) and inclusion compound (IC) of poorly water-soluble tadalafil using various biol…
View article: PP407 Novel docetaxel-loaded double-reverse thermoreversible system for intramuscular treatment: Development and antitumor evaluation
PP407 Novel docetaxel-loaded double-reverse thermoreversible system for intramuscular treatment: Development and antitumor evaluation Open
View article: Novel biocompatible multifunctional porous magnetic nanoclusters for the targeted delivery of lenvatinib towards hepatocellular carcinoma
Novel biocompatible multifunctional porous magnetic nanoclusters for the targeted delivery of lenvatinib towards hepatocellular carcinoma Open
Graphical abstract of the development and characterization of novel biocompatible multifunctional porous magnetic nanoclusters towards hepatocellular carcinoma.
View article: Response of Tomato to Crude and Fine Phosphatic Fertilizers Integrated with Cattle Manure and Indole Acetic Acid
Response of Tomato to Crude and Fine Phosphatic Fertilizers Integrated with Cattle Manure and Indole Acetic Acid Open
Phosphatic fertilizers are an integral part of crop cycle and are responsible for food production. But due to continuous increase in prizes of fertilizer over the years, the economics of the farmer is affected and there is a dire need to f…
View article: Evaluating the Efficacy of Nano-Cyclosporine A in Mice Model of Ulcerative Colitis: A Systematic Review and Meta-Analysis
Evaluating the Efficacy of Nano-Cyclosporine A in Mice Model of Ulcerative Colitis: A Systematic Review and Meta-Analysis Open
Background Cyclosporine A is an immunosuppressive drug used in clinics to treat steroid-refractory ulcerative colitis (UC). However, due to its side effects, researchers are evaluating novel drug delivery-based treatment options. Nanoparti…
View article: Comparison of Solid Self-Nanoemulsifying Systems and Surface-Coated Microspheres: Improving Oral Bioavailability of Niclosamide
Comparison of Solid Self-Nanoemulsifying Systems and Surface-Coated Microspheres: Improving Oral Bioavailability of Niclosamide Open
This solid SNEDDS formulation may be an excellent candidate for niclosamide with improved oral bioavailability for repurposing.
View article: Nanocarrier-Mediated Enhancement of Fusidic Acid’s Anti-Bacterial Activity: A Comparative Analysis of Its Niosomal and Liposomal Delivery Systems
Nanocarrier-Mediated Enhancement of Fusidic Acid’s Anti-Bacterial Activity: A Comparative Analysis of Its Niosomal and Liposomal Delivery Systems Open
Biofilms are group of bacteria that are protected by a slimy layer. These biofilms are more resistant to antibiotics than individual bacteria which are the basic building blocks of biofilms. Researchers are actively introducing new treatme…
View article: Daidzein ameliorates experimental traumatic brain injury‐induced neurological symptoms by suppressing oxidative stress and apoptosis
Daidzein ameliorates experimental traumatic brain injury‐induced neurological symptoms by suppressing oxidative stress and apoptosis Open
Traumatic brain injury (TBI) causes deficits in neurological function, induces pathological changes, and increases oxidative stress. The current investigation aimed to determine Daidzein's neuroprotective potential in experimental TBI. Ini…
View article: Pharmacological Effects of Matrine in Nitroglycerine-induced Migraine Pain by Inhibiting Cytokines and Oxidative Stress
Pharmacological Effects of Matrine in Nitroglycerine-induced Migraine Pain by Inhibiting Cytokines and Oxidative Stress Open
View article: Co-delivery of paclitaxel and curcumin loaded solid lipid nanoparticles for improved targeting of lung cancer: In vitro and in vivo investigation
Co-delivery of paclitaxel and curcumin loaded solid lipid nanoparticles for improved targeting of lung cancer: In vitro and in vivo investigation Open
View article: Corrigendum to Development and Evaluation of Tacrolimus Loaded Nano-Transferosomes for Skin Targeting and Dermatitis Treatment [Journal of Pharmaceutical Sciences 113 (2024) 471–485/XPHS_3228]
Corrigendum to Development and Evaluation of Tacrolimus Loaded Nano-Transferosomes for Skin Targeting and Dermatitis Treatment [Journal of Pharmaceutical Sciences 113 (2024) 471–485/XPHS_3228] Open
View article: Nano biomaterials based strategies for enhanced brain targeting in the treatment of neurodegenerative diseases: an up-to-date perspective
Nano biomaterials based strategies for enhanced brain targeting in the treatment of neurodegenerative diseases: an up-to-date perspective Open
View article: Impact of Pharmacist-led educational services in promoting breast cancer awareness
Impact of Pharmacist-led educational services in promoting breast cancer awareness Open
Background Breast cancer is rapidly increasing worldwide. Pakistan has a high incidence rate of 1 in every nine women. The lack of awareness is the remarkable reason for delayed diagnosis, thus resulting in high mortality. In this study, w…
View article: Nitazoxanide and quercetin co-loaded nanotransfersomal gel for topical treatment of cutaneous leishmaniasis with macrophage targeting and enhanced anti-leishmanial effect
Nitazoxanide and quercetin co-loaded nanotransfersomal gel for topical treatment of cutaneous leishmaniasis with macrophage targeting and enhanced anti-leishmanial effect Open
It can be concluded that nanotransfersomal gel has the capability to retain and permeate the incorporated drugs through stratum corneum and induce synergetic anti-leishmanial effect of NTZ and QUR against cutaneous leishmaniasis.
View article: Melatonin delivered in solid lipid nanoparticles ameliorated its neuroprotective effects in cerebral ischemia
Melatonin delivered in solid lipid nanoparticles ameliorated its neuroprotective effects in cerebral ischemia Open
The current study explores the potential of melatonin (MLT)-loaded solid lipid nanoparticles (MLT-SLNs) for better neuroprotective effects in ischemic stroke. MLT-SLNs were prepared using lipid matrix of palmityl alcohol with a mixture of …
View article: Investigation of the treatment potential of Raloxifene-loaded polymeric nanoparticles in osteoporosis: In-vitro and in-vivo analyses
Investigation of the treatment potential of Raloxifene-loaded polymeric nanoparticles in osteoporosis: In-vitro and in-vivo analyses Open
Osteoporosis (OP), is a systemic bone disorder associated with low bone mass and bone tissue corrosion. Worsening of the disease condition leads to bone delicacy and fracture. Various drugs are available for the treatment of OP, however th…
View article: Metformin HCl-loaded transethosomal gel; development, characterization, and antidiabetic potential evaluation in the diabetes-induced rat model
Metformin HCl-loaded transethosomal gel; development, characterization, and antidiabetic potential evaluation in the diabetes-induced rat model Open
Herein we designed, optimized, and characterized the Metformin Hydrochloride Transethosomes (MTF-TES) and incorporate them into Chitosan gel to develop Metformin Hydrochloride loaded Transethosomal gel (MTF-TES gel) that provides a sustain…
View article: Retraction Note: Transdermal delivery of allopurinol-loaded nanostructured lipid carrier in the treatment of gout
Retraction Note: Transdermal delivery of allopurinol-loaded nanostructured lipid carrier in the treatment of gout Open
View article: Retraction Note: Suppression of NF-κB signaling by ECN in an arthritic model of inflammation
Retraction Note: Suppression of NF-κB signaling by ECN in an arthritic model of inflammation Open
View article: A detailed insight of the tumor targeting using nanocarrier drug delivery system
A detailed insight of the tumor targeting using nanocarrier drug delivery system Open
Human struggle against the deadly disease conditions is continued since ages. The contribution of science and technology in fighting against these diseases cannot be ignored exclusively due to the invention of novel procedure and products,…
View article: Preparation, Pharmacokinetics, and Antitumor Potential of Miltefosine-Loaded Nanostructured Lipid Carriers [Retraction]
Preparation, Pharmacokinetics, and Antitumor Potential of Miltefosine-Loaded Nanostructured Lipid Carriers [Retraction] Open
[This retracts the article DOI: 10.2147/IJN.S299443.].
View article: Co-delivery of amphotericin B and pentamidine loaded niosomal gel for the treatment of <i>Cutaneous leishmaniasis</i>
Co-delivery of amphotericin B and pentamidine loaded niosomal gel for the treatment of <i>Cutaneous leishmaniasis</i> Open
Topical drug delivery is preferable route over systemic delivery in case of Cutaneous leishmaniasis (CL). Among the available agents, amphotericin B (AmB) and pentamidine (PTM) showed promising result against CL. However, monotherap…
View article: RETRACTED ARTICLE: Transdermal delivery of allopurinol-loaded nanostructured lipid carrier in the treatment of gout
RETRACTED ARTICLE: Transdermal delivery of allopurinol-loaded nanostructured lipid carrier in the treatment of gout Open
Background Allopurinol (ALP), a xanthine oxidase inhibitor, is a first line drug for the treatment of gout and hyperuricemia. Being the member of BCS class II drugs, ALP has solubility problem, which affects its bioavailability. Also, ALP …