Explanipedia

Defining epidemiological cutoff values for Brucella melitensis: an European multicentre study Open

Flavia Dematheis, Joseph Papaparaskevas, Erika Matuschek, Tara Wahab, Inga Fröding , et al. · 2025

Genomic epidemiology of Brucella suis biovar 2 in German swine and wildlife, 2003–2023 Open

Falk Melzer, Jörg Linde, Hanka Brangsch · 2025

Introduction Porcine brucellosis, caused by Brucella suis biovar 2, is currently the only type of brucellosis officially reported in farm animals in Germany, with outbreaks confirmed through direct pathogen detection. In most European coun…

Serological, phenotypic and molecular characterization of brucellosis in small ruminants in northern Algeria Open

Ibrahim Nabi, Rachid Achek, Abdelkadir Karim, Falk Melzer, Hanka Brangsch , et al. · 2025

Brucellosis is considered a common bacterial zoonotic disease of high prevalence in countries of the Middle East and the Mediterranean region with economic and public health impact. The present study aimed to investigate the current situat…

A bibliometric analysis of brucellosis research (1991–2022): Research trends and hotspots Open

Muhammad Farooq, Aman Ullah Khan, Hosny El‐Adawy, Falk Melzer, Heinrich Neubauer , et al. · 2024

Brucellosis is an important, highly contagious, bacterial zoonotic disease that has economic and public health implications. It is caused by various Brucella species with a wide host range including livestock, wildlife, other terrestrial a…

Genomic analysis of Brucella isolates from animals and humans, Türkiye, 2010 to 2020 Open

Kadir Akar, Hanka Brangsch, Tariq Jamil, Gülseren Yıldız Öz, Emin Ayhan Baklan , et al. · 2024

Background Brucellosis is a bacterial zoonosis causing severe illness in humans and animals and leading to economic losses in the livestock production in Türkiye and other endemic countries. Aim We aimed at investigating genomic difference…

Seroprevalence and molecular detection of brucellosis among Pakistani women with spontaneous abortion Open

Mohammad Ejaz, Shahzad Ali, Muhammad Ali Syed, Falk Melzer, Rani Faryal , et al. · 2024

Background Human brucellosis is a neglected disease transmitted to humans from animals such as cattle, goats, dogs, and swine. The causative agents are bacteria of the genus Brucella , intracellular pathogens usually confined to the reprod…

Issue Information Open

Abraham J. Domb, Jianhua Dong, China Feng, C.T. Fontaine, France Takeoka , et al. · 2023

An anti

Genotypic peculiarities of a human brucellosis case caused by Brucella suis biovar 5 Open

Hanka Brangsch, Matthias A. Horstkotte, Falk Melzer · 2023

The emergence of <i>Brucella canis</i> as a public health threat in Europe: what we know and what we need to learn Open

Vitomir Djokić, Luca Freddi, Fabrizio De Massis, Elina Lahti, Marielle H. van den Esker , et al. · 2023

The zoonotic bacteria, Brucella canis, is becoming the leading cause of canine brucellosis in Europe. In dogs, it causes reproductive problems as well as non-specific lameness or discospondilitis. In humans, B. canis can be o…

Genotype diversity of brucellosis agents isolated from humans and animals in Greece based on whole-genome sequencing Open

Hanka Brangsch, Vassilios Sandalakis, Maria Babetsa, Evridiki Boukouvala, Artemisia Ntoula , et al. · 2023

Brucella suis biovar 1 infection in a dog with orchitis in Germany Open

Sophie Aurich, Juliane Schneider, Hanka Brangsch, Ad P. Koets, Falk Melzer , et al. · 2023

In 2021, a case of canine brucellosis diagnosed in a dog with orchitis was presented to a veterinary practice in Germany. Serological testing excluded Brucella ( B .) canis as a causative agent, but molecular analysis revealed the presence…

Evidence of Brucellosis in Hospitalized Patients of Selected Districts of Punjab, Pakistan Open

Amna Azam, Shahid Saleem Pall, Iahtasham Khan, Waqas Ahmad, Tariq Jamil , et al. · 2023

Brucellosis is a bacterial zoonosis worldwide and a potential health risk in Pakistan due to socio-economic reasons and lack of awareness, veterinary health and modern dairy-processing facilities. The aim of this study was to determine the…

If You're Not Confused, You're Not Paying Attention: <i>Ochrobactrum</i> Is Not Brucella Open

Edgardo Moreno, Earl A. Middlebrook, Pamela Altamirano-Silva, Sascha Al Dahouk, George F. Araj , et al. · 2023

Bacteria of the genus Brucella are facultative intracellular parasites that cause brucellosis, a severe animal and human disease. Recently, a group of taxonomists merged the brucellae with the primarily free-living, phylogenetically relate…

White-Toothed Shrews (Genus Crocidura): Potential Reservoirs for Zoonotic Leptospira spp. and Arthropod-Borne Pathogens? Open

Viola C. Haring, Jens Jacob, Bernd Walther, Martin Trost, Michael Stubbe , et al. · 2023

Three species of white-toothed shrews of the order Eulipotyphla are present in central Europe: the bicolored (Crocidura leucodon), greater (Crocidura russula) and lesser (Crocidura suaveolens) white-toothed shrews. Their precise distributi…

Comparison of Illumina and Oxford Nanopore Technology for genome analysis of Francisella tularensis, Bacillus anthracis, and Brucella suis Open

Jörg Linde, Hanka Brangsch, Martin Hölzer, Christine Thomas, Mandy C. Elschner , et al. · 2023

Background Bacterial epidemiology needs to understand the spread and dissemination of strains in a One Health context. This is important for highly pathogenic bacteria such as Bacillus anthracis , Brucella species , and Francisella tularen…

D-JRP17-WP7.Del6: Report of the last annual workshop including exchanges between partners and inputs from external stakeholders Open

Vitomir Djokić, Ferreira Ana Cristina, Pelerito Ana, Falk Melzer, Whatmore Adrian , et al. · 2023

Work Package 7, Deliverable 6, final workshop meeting report with all the presentations

D-JRP17-WP4.Del1: Phenotyping scheme to differentiate emerging Brucella sp. from classical species Open

Falk Melzer, Al Dahouk Sascha, Dirk Hofreuter · 2023

WP4, Deliverable 1 report

D-JRP17-WP4.Del2: AMR testing protocoll including proposals for ECOFFs for emerging Brucella spp. Open

Falk Melzer, Dirk Hofreuter, Al Dahouk Sascha · 2023

WP4, Deliverable 2 report

D-JRP17-WP3.Del4: Rapid detection assay(s) for atypical strains using clade specific markers Open

Ashford Roland, Guillaume Girault, Luca Freddi, Falk Melzer, Garofolo Giuliano , et al. · 2023

WP3 Deliverable 4 report

Project Deliverable D-JRP17-WP3.Del2 - HARMONISATION AND STANDARDISATION OF PROTOCOLS FOR WHOLE GENOME SEQUENCING Open

Ashford Roland, Guillaume Girault, Falk Melzer, Garofolo Giuliano, Ferreira Ana Cristina , et al. · 2023

D-JRP17-WP5.Del2: Development of a macrophage based in vitro system for rapid assessment of zoonotic potential Open

van den Esker Marielle, Koomen Jeroen, Koets Ad, Luca Freddi, Vitomir Djokić , et al. · 2023

WP5, Deliverable 2 report

D-JRP17-WP3.Del3: Molecular typing data from emerging Brucella isolates Open

Ashford Roland, Guillaume Girault, Luca Freddi, Falk Melzer, Garofolo Giuliano , et al. · 2023

WP3, Deliverable 3 report

Additional file 2 of Comparison of Illumina and Oxford Nanopore Technology for genome analysis of Francisella tularensis, Bacillus anthracis, and Brucella suis Open

Jörg Linde, Hanka Brangsch, Martin Hölzer, Christine Thomas, Mandy C. Elschner , et al. · 2023

Additional file 2: Table S2. Quality measures of assembled genomes.

Additional file 5 of Comparison of Illumina and Oxford Nanopore Technology for genome analysis of Francisella tularensis, Bacillus anthracis, and Brucella suis Open

Jörg Linde, Hanka Brangsch, Martin Hölzer, Christine Thomas, Mandy C. Elschner , et al. · 2023

Additional file 5: Table S5. Multi Locus Variable Copy Numbers of Tandem Repeats Analysis (MLVA).

Additional file 4 of Comparison of Illumina and Oxford Nanopore Technology for genome analysis of Francisella tularensis, Bacillus anthracis, and Brucella suis Open

Jörg Linde, Hanka Brangsch, Martin Hölzer, Christine Thomas, Mandy C. Elschner , et al. · 2023

Additional file 4: Table S4. Canonical SNP (canSNP) -typing, Multilocus Sequence Typing (MLST).

Additional file 1 of Comparison of Illumina and Oxford Nanopore Technology for genome analysis of Francisella tularensis, Bacillus anthracis, and Brucella suis Open

Jörg Linde, Hanka Brangsch, Martin Hölzer, Christine Thomas, Mandy C. Elschner , et al. · 2023

Additional file 1: Table S1. Quality measures of raw sequencing data.

Additional file 1 of Genotype diversity of brucellosis agents isolated from humans and animals in Greece based on whole-genome sequencing Open

Hanka Brangsch, Vassilios Sandalakis, Maria Babetsa, Evridiki Boukouvala, Artemisia Ntoula , et al. · 2023

Additional file 1: Table: Sequencing quality data. Quality metrics of sequencing data and de novo assemblies of the investigated strains, including affiliation to MLST sequence types and cgMLST clusters.

Additional file 4 of Genotype diversity of brucellosis agents isolated from humans and animals in Greece based on whole-genome sequencing Open

Hanka Brangsch, Vassilios Sandalakis, Maria Babetsa, Evridiki Boukouvala, Artemisia Ntoula , et al. · 2023

Additional file 4: Table: Foreign strains used in this study. Metadata and accession numbers for foreign strains used in this study

Additional file 3 of Comparison of Illumina and Oxford Nanopore Technology for genome analysis of Francisella tularensis, Bacillus anthracis, and Brucella suis Open

Jörg Linde, Hanka Brangsch, Martin Hölzer, Christine Thomas, Mandy C. Elschner , et al. · 2023

Additional file 3: Table S3. Genetic markers for virulence and plasmids.

Additional file 6 of Comparison of Illumina and Oxford Nanopore Technology for genome analysis of Francisella tularensis, Bacillus anthracis, and Brucella suis Open

Jörg Linde, Hanka Brangsch, Martin Hölzer, Christine Thomas, Mandy C. Elschner , et al. · 2023

Additional file 6: Table S6. Pairwise distances of cgMLST and cgSNP typing.

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