Fangfang Yu
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View article: DEP-CEEMDAN-MPE-INHT a time-frequency analysis method for noisy blasting seismic waves with adaptive noise suppression and endpoint processing
DEP-CEEMDAN-MPE-INHT a time-frequency analysis method for noisy blasting seismic waves with adaptive noise suppression and endpoint processing Open
The Hilbert-Huang transform (HHT) is widely used for time-frequency analysis of blasting seismic wave signals due to its unique adaptability. However, blasting seismic wave signals are typical non-stationary vibration signals that are susc…
View article: Engineering Safety-Oriented Blasting-Induced Seismic Wave Signal Processing: An EMD Endpoint Suppression Method Based on Multi-Scale Feature
Engineering Safety-Oriented Blasting-Induced Seismic Wave Signal Processing: An EMD Endpoint Suppression Method Based on Multi-Scale Feature Open
Blasting-induced seismic waves are typically nonlinear and non-stationary signals. The EMD-Hilbert transform is commonly used for time–frequency analysis of such signals. However, during the empirical mode decomposition (EMD) processing of…
View article: Selenomethionine alleviates T-2 toxin-induced articular chondrocyte ferroptosis via the system Xc−/GSH/GPX4 axis
Selenomethionine alleviates T-2 toxin-induced articular chondrocyte ferroptosis via the system Xc−/GSH/GPX4 axis Open
T-2 toxin can induce bone and cartilage development disorder, and oxidative stress plays an important role in it. It is well known that selenomethionine (Se-Met) has antioxidative stress properties and promotes the repair of cartilage lesi…
View article: Fluoride exposure, personal susceptibility and osteoarticular degeneration: Evidence from farmers in the Yellow River Basin of Henan Province
Fluoride exposure, personal susceptibility and osteoarticular degeneration: Evidence from farmers in the Yellow River Basin of Henan Province Open
Osteoarticular degeneration (OAD) is an important issue. Excessive fluoride can damage osteoarticular health. Besides, personal susceptibility (including genetic factors, physiological characteristics, and lifestyle) also contributes to os…
View article: Apoptosis and Inflammation Involved with Fluoride-Induced Bone Injuries
Apoptosis and Inflammation Involved with Fluoride-Induced Bone Injuries Open
Background: Excessive fluoride exposure induces skeletal fluorosis, but the specific mechanism responsible is still unclear. Therefore, this study aimed to identify the pathogenesis of fluoride-induced bone injuries. Methods: We systematic…
View article: Glutamine metabolism in fluorosis: Integrated metabolomics and transcriptomics analysis
Glutamine metabolism in fluorosis: Integrated metabolomics and transcriptomics analysis Open
L-glutamine emerges as a potential biomarker for fluorosis. Glutamine metabolism was involved in the pathogenesis of fluorosis.
View article: Network analysis of smoking-related sleep characteristics in Chinese adults
Network analysis of smoking-related sleep characteristics in Chinese adults Open
The associations between multiple sleep characteristics and smoking behavior are inconsistent, and it is unclear which sleep characteristics are most crucial for tobacco prevention. This study aimed to explore the associations between smok…
View article: Passive exercise is an effective alternative to HRT for restoring OVX induced mitochondrial dysfunction in skeletal muscle
Passive exercise is an effective alternative to HRT for restoring OVX induced mitochondrial dysfunction in skeletal muscle Open
Background Postmenopausal women are more prone to develop muscle weakness, which is strongly associated with impairment of mitochondrial function in skeletal muscle. This study aimed to examine the impact of a passive exercise modality, wh…
View article: Research on Deep Learning-based English Vocabulary Teaching Aid System in Colleges and Universities
Research on Deep Learning-based English Vocabulary Teaching Aid System in Colleges and Universities Open
Currently, English teaching in colleges and universities faces the challenge of low efficiency in vocabulary teaching. Deep learning technology, an advanced artificial intelligence technology, provides new ideas for solving this problem. C…
View article: Association between increased CD177+ neutrophils and chronic activation in people living with HIV
Association between increased CD177+ neutrophils and chronic activation in people living with HIV Open
To the Editor: Neutrophils, as innate cells, play an important role in the immune defensive response against invading pathogens and provide signals for the proliferation and activation of T and B cells to initiate adaptive immunity.[1] Neu…
View article: Monocyte‐to‐lymphocyte ratio and gastrointestinal disorder‐related hospitalization in patients on maintenance hemodialysis
Monocyte‐to‐lymphocyte ratio and gastrointestinal disorder‐related hospitalization in patients on maintenance hemodialysis Open
Introduction To explore the association between monocyte‐to‐lymphocyte ratio (MLR) and the risk of hospitalization due to gastrointestinal (GI) disorder in hemodialysis (HD) patients. Methods In this multicenter, observational cohort study…
View article: Decreased intracellular water is associated with sarcopenic obesity in chronic haemodialysis patients
Decreased intracellular water is associated with sarcopenic obesity in chronic haemodialysis patients Open
Objective To explore the association between intracellular water (ICW) and sarcopenic obesity in patients undergoing chronic haemodialysis (HD). Methods A multicentre, cross-sectional study of 3354 adult chronic HD patients was conducted i…
View article: Decreased Intracellular to Total Body Water Ratio and Depressive Symptoms in Patients with Maintenance Hemodialysis
Decreased Intracellular to Total Body Water Ratio and Depressive Symptoms in Patients with Maintenance Hemodialysis Open
In MHD patients, the decreased ratio of ICW/TBW was independently related to high depression rates.
View article: Low intracellular water and incident cognitive impairment in chronic hemodialysis patients
Low intracellular water and incident cognitive impairment in chronic hemodialysis patients Open
Objective To explore the effect of intracellular water (ICW) evaluated by the bioelectrical Impedance Spectroscopy (BIS) on the risk of incident cognitive impairment (CI) in chronic hemodialysis (HD) patients. Methods Three thousand three …
View article: Expression Profiles of Long Non-Coding RNAs in the Articular Cartilage of Rats Exposed to T-2 Toxin
Expression Profiles of Long Non-Coding RNAs in the Articular Cartilage of Rats Exposed to T-2 Toxin Open
T-2 toxin could induce bone damage. But there is no specific mechanism about the long non-coding RNAs (lncRNAs) involved in T-2 toxin-induced articular cartilage injury. In this study, 24 SD rats were randomly divided into a control group …
View article: Selenomethionine Antagonized microRNAs Involved in Apoptosis of Rat Articular Cartilage Induced by T-2 Toxin
Selenomethionine Antagonized microRNAs Involved in Apoptosis of Rat Articular Cartilage Induced by T-2 Toxin Open
T-2 toxin and selenium deficiency are considered important etiologies of Kashin–Beck disease (KBD), although the exact mechanism is still unclear. To identify differentially expressed microRNAs (DE-miRNAs) in the articular cartilage of rat…
View article: In Silico Analysis of Ferroptosis-Related Genes and Its Implication in Drug Prediction against Fluorosis
In Silico Analysis of Ferroptosis-Related Genes and Its Implication in Drug Prediction against Fluorosis Open
Fluorosis is a serious global public health problem. Interestingly, so far, there is no specific drug treatment for the treatment of fluorosis. In this paper, the potential mechanisms of 35 ferroptosis-related genes in U87 glial cells expo…
View article: Integrated 16S rDNA sequencing and metabolomics to explore the intestinal changes in children and rats with dental fluorosis
Integrated 16S rDNA sequencing and metabolomics to explore the intestinal changes in children and rats with dental fluorosis Open
Dental fluorosis (DF) is a widely prevalent disease caused by excessive fluoride with limited awareness of its underlying pathogenesis. Here, a pilot population study was conducted to explore the pathogenesis of DF from the perspective of …
View article: Low Lean Tissue Index and Muscle Strength Combined with High Fat Tissue Index Are Associated with Cardiovascular Disease-Related Hospitalisation in Patients on Haemodialysis
Low Lean Tissue Index and Muscle Strength Combined with High Fat Tissue Index Are Associated with Cardiovascular Disease-Related Hospitalisation in Patients on Haemodialysis Open
Introduction: The combined clinical impact of muscle mass, muscle function, and adipose mass on hospitalisation events, especially those that have exact causes, such as cardiovascular diseases (CVDs), had been rarely studied in patients on…
View article: Detection of left atrial appendage thrombus by dual-energy computed tomography-derived imaging biomarkers in patients with atrial fibrillation
Detection of left atrial appendage thrombus by dual-energy computed tomography-derived imaging biomarkers in patients with atrial fibrillation Open
Aims This study aimed to assess the diagnostic performances of dual-energy computed tomography (CT)-derived iodine concentration and effective atomic number (Z eff ) in early-phase cardiac CT in detecting left atrial appendage (LAA) thromb…
View article: Do methylenetetrahydrofolate dehydrogenase, cyclohydrolase, and formyltetrahydrofolate synthetase 1 polymorphisms modify changes in intelligence of school-age children in areas of endemic fluorosis?
Do methylenetetrahydrofolate dehydrogenase, cyclohydrolase, and formyltetrahydrofolate synthetase 1 polymorphisms modify changes in intelligence of school-age children in areas of endemic fluorosis? Open
Background: Excessive exposure to fluoride can reduce intelligence. Methylenetetrahydrofolate dehydrogenase, cyclohydrolase, and formyltetrahydrofolate synthetase 1 ( MTHFD1 ) polymorphisms have important roles in neurodevelopment. However…
View article: Clinical value of resting cardiac dual-energy CT in patients suspected of coronary artery disease
Clinical value of resting cardiac dual-energy CT in patients suspected of coronary artery disease Open
Background Rest/stress myocardial CT perfusion (CTP) has high diagnostic value for coronary artery disease (CAD), but the additional value of resting CTP especially dual-energy CTP (DE-CTP) beyond coronary CT angiography (CCTA) in chest pa…
View article: The first human induced pluripotent stem cell line of Kashin–Beck disease reveals involvement of heparan sulfate proteoglycan biosynthesis and PPAR pathway
The first human induced pluripotent stem cell line of Kashin–Beck disease reveals involvement of heparan sulfate proteoglycan biosynthesis and PPAR pathway Open
Kashin–Beck disease (KBD) is an endemic osteochondropathy. Due to a lack of suitable animal or cellular disease models, the research progress on KBD has been limited. Our goal was to establish the first disease‐specific human induced pluri…