Feng Xie
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View article: Effect of group music therapy combined with routine nursing on emotional stability in inpatients with manic episodes
Effect of group music therapy combined with routine nursing on emotional stability in inpatients with manic episodes Open
Patients experiencing manic episodes often suffer from significant emotional instability, impairing treatment adherence and prolonging hospitalization. Nonpharmacological interventions such as music therapy may offer additional benefits. T…
View article: Dysfunctional T cells due to the abnormal glucose metabolism in patients with primary immune thrombocytopenia
Dysfunctional T cells due to the abnormal glucose metabolism in patients with primary immune thrombocytopenia Open
Summary To investigate T‐cell glucose metabolism dysfunction in primary immune thrombocytopenia (ITP) and the role of mammalian target of rapamycin complex 1 (mTORC1) in regulatory T‐cell (Treg) suppression function. Gene set enrichment an…
View article: Global temporal trends and projections of gastroesophageal reflux disease prevalence: Age-period-cohort analysis 2021
Global temporal trends and projections of gastroesophageal reflux disease prevalence: Age-period-cohort analysis 2021 Open
Background Gastroesophageal reflux disease (GERD) represents a major global health challenge with varied regional epidemiological patterns. This study aimed to comprehensively analyze temporal trends, health inequalities, and driving facto…
View article: Protocol for an economic evaluation alongside the Re-Evaluating the Inhibition of Stress Erosions (E-REVISE) trial
Protocol for an economic evaluation alongside the Re-Evaluating the Inhibition of Stress Erosions (E-REVISE) trial Open
Introduction Economic evaluations in healthcare can guide practice and inform policy. The objective of this paper is to present the protocol for a health economic evaluation comparing the cost-effectiveness of prophylactic treatment using …
View article: Pediatric MASLD in China: epidemiology, screening, diagnosis, and management
Pediatric MASLD in China: epidemiology, screening, diagnosis, and management Open
Metabolic dysfunction-associated steatotic liver disease (MASLD) is an emerging global epidemic, with a rapidly increasing burden among children and adolescents in China. This alarming trend is primarily driven by profound lifestyle shifts…
View article: Associations between clinical benefits of cancer drugs and incremental quality-adjusted life years used in reimbursement decisions in Australia, Canada, England and China: an observational study
Associations between clinical benefits of cancer drugs and incremental quality-adjusted life years used in reimbursement decisions in Australia, Canada, England and China: an observational study Open
Objectives To investigate the association between incremental quality-adjusted life years (QALYs) predicted in economic evaluations and clinical benefits assessed by the European Society for Medical Oncology-Magnitude of Clinical Benefit S…
View article: Measuring and Valuing Health Using EuroQol Instruments: New Developments 2025 and Beyond
Measuring and Valuing Health Using EuroQol Instruments: New Developments 2025 and Beyond Open
The health-related quality of life (HRQoL) instruments developed by EuroQol, an international not-for-profit organisation, have earned a unique position in health economics and outcomes research. The original instrument, EQ-5D-3L, aimed to…
View article: Protocol for an Economic Evaluation Alongside the Re-Evaluating the Inhibition of Stress Erosions (E-REVISE) Trial
Protocol for an Economic Evaluation Alongside the Re-Evaluating the Inhibition of Stress Erosions (E-REVISE) Trial Open
Introduction Economic evaluations in healthcare can guide practice and inform policy. The objective of this paper is to present the protocol for a health economic evaluation comparing the cost-effectiveness of prophylactic treatment using …
View article: Global, regional, and national burden of mortality and DALYs attributable to high body mass index from 1990 to 2021 with projections to 2036
Global, regional, and national burden of mortality and DALYs attributable to high body mass index from 1990 to 2021 with projections to 2036 Open
The increasing prevalence of high BMI has resulted in significant health burdens over the past three decades, with cardiovascular diseases, diabetes and kidney diseases being primary contributors. Low- and middle-income regions bear a larg…
View article: Effectiveness of home-based exercise combined with nutritional care intervention in elderly patients with gastric cancer and sarcopenia: a retrospective study
Effectiveness of home-based exercise combined with nutritional care intervention in elderly patients with gastric cancer and sarcopenia: a retrospective study Open
Background Sarcopenia and malnutrition are prevalent among elderly patients with gastric cancer, significantly impairing recovery and quality of life (QoL). Effective interventions targeting both nutritional and physical deficiencies are c…
View article: A Retrospective Analysis of the Effectiveness and Safety of Plerixafor Combined with PEGylated rhG-CSF for Autologous Hematopoietic Stem Cell Mobilization in Patients with Multiple Myeloma
A Retrospective Analysis of the Effectiveness and Safety of Plerixafor Combined with PEGylated rhG-CSF for Autologous Hematopoietic Stem Cell Mobilization in Patients with Multiple Myeloma Open
Purpose The study aims to assess the clinical efficacy and safety profile of plerixafor in combination with polyethylene glycolated recombinant human granulocyte colony-stimulating factor (PEGylated rhG-CSF) for autologous hematopoietic st…
View article: Health economics evaluation of diagnostic strategies for gastro-oesophageal reflux disease with reflux symptoms in China: a modelling study
Health economics evaluation of diagnostic strategies for gastro-oesophageal reflux disease with reflux symptoms in China: a modelling study Open
Objectives American College of Gastroenterology (ACG) and Chinese expert consensus recommended different algorithmic approaches for the diagnosis of gastro-oesophageal reflux disease (GERD) are not yet defined. We compared the two recommen…
View article: Effect of an Online Mobility Self-Management Program on Walking Speed in Older Adults With Preclinical Mobility Limitation: Protocol for a Randomized Controlled Trial
Effect of an Online Mobility Self-Management Program on Walking Speed in Older Adults With Preclinical Mobility Limitation: Protocol for a Randomized Controlled Trial Open
Background Walking difficulties are a common and costly problem. However, disability associated with the decline in walking ability is not an inevitable consequence. With an aging population, it is increasingly important to establish strat…
View article: Longitudinal description of health-related quality of life and depressive symptoms in polyQ spinocerebellar ataxia patients
Longitudinal description of health-related quality of life and depressive symptoms in polyQ spinocerebellar ataxia patients Open
Introduction Due to limited treatment options, managing symptoms has dominated care for Spinocerebellar Ataxia (SCA). Little attention has been given to health-related quality of life (HRQoL) and depressive symptoms experienced by patients…
View article: Exploring the feasibility of using discrete choice experiment (DCE) to elicit preferences among children and adolescents: protocol for a convergent parallel mixed methods study
Exploring the feasibility of using discrete choice experiment (DCE) to elicit preferences among children and adolescents: protocol for a convergent parallel mixed methods study Open
Introduction Discrete choice experiments (DCEs) are increasingly used to elicit value sets for paediatric health-related quality of life instruments, including the EQ-5D-Y. In a multinational pilot study that compared EQ-5D-Y-5L health sta…
View article: A Retrospective Analysis of the Effectiveness and Safety of Plerixafor Combined with PEGylated rhG-CSF for Autologous Hematopoietic Stem Cell Mobilization in Chinese Patients with Multiple Myeloma
A Retrospective Analysis of the Effectiveness and Safety of Plerixafor Combined with PEGylated rhG-CSF for Autologous Hematopoietic Stem Cell Mobilization in Chinese Patients with Multiple Myeloma Open
Purpose The study aims to assess the clinical efficacy and safety profile of plerixafor in combination with polyethylene glycolated recombinant human granulocyte colony-stimulating factor (PEGylated rhG-CSF) for autologous hematopoietic st…
View article: Tumor-infiltrating lymphocytes in breast cancer through artificial intelligence: biomarker analysis from the results of the TIGER challenge
Tumor-infiltrating lymphocytes in breast cancer through artificial intelligence: biomarker analysis from the results of the TIGER challenge Open
The prognostic significance of tumor-infiltrating lymphocytes (TILs) in breast cancer has been recognized for over a decade. Although histology-based scoring recommendations exist to standardize visual TILs assessment, interobserver agreem…
View article: Correlation between self-efficacy and professional identity of nurse anesthetists
Correlation between self-efficacy and professional identity of nurse anesthetists Open
Objective To investigate the current situation and influencing factors of professional identity, and to explore the correlation between self-efficacy and professional identity of nurse anesthetists, so as to provide theoretical basis for i…
View article: Commonly used interventional procedures for non-cancer chronic spine pain: a clinical practice guideline
Commonly used interventional procedures for non-cancer chronic spine pain: a clinical practice guideline Open
Clinical question What is the comparative effectiveness and safety of commonly used interventional procedures (such as spinal injections and ablation procedures) for chronic axial and radicular spine pain that is not associated with cancer…
View article: Measuring Regional Variations in US Population-Level Health-Related Quality of Life During COVID-19 Using the EQ-5D-5L
Measuring Regional Variations in US Population-Level Health-Related Quality of Life During COVID-19 Using the EQ-5D-5L Open
Regional variations in coronavirus disease 2019 (COVID-19) suggest non-uniform impacts on health-related quality-of-life (HRQoL) across the US. This study measured regional variations in US population-level HRQoL during COVID-19. HRQoL was…
View article: Clinical Characteristics, Treatment Outcomes, And Prognostic Factors of Laryngeal Neuroendocrine Carcinoma: A Population-Based Analysis
Clinical Characteristics, Treatment Outcomes, And Prognostic Factors of Laryngeal Neuroendocrine Carcinoma: A Population-Based Analysis Open
Objective. Laryngeal neuroendocrine carcinoma (LNEC) is a rare and aggressive malignancy with poor prognosis.This study investigates the clinical characteristics, treatments and prognostic factors of LNEC patients. Methods. Data from the S…
View article: Recommendations for essential medicines for multiple sclerosis in low-resource settings
Recommendations for essential medicines for multiple sclerosis in low-resource settings Open
Background: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that, when untreated, can lead to significant disability in young adults. Despite the increase in the number of disease-modifying therapies (DMTs)…
View article: The Role of Sex Hormones and Sex Hormone-binding Globulin in Functional Gatrointestinal Disorders: A Bidirectional Two-sample Mendelian Randomization Study
The Role of Sex Hormones and Sex Hormone-binding Globulin in Functional Gatrointestinal Disorders: A Bidirectional Two-sample Mendelian Randomization Study Open
Background and Aims: Sex hormones and sex hormone-binding globulin (SHBG) have been confirmed to involve in the pathophysiology of functional gastrointestinal disorders (FGIDs), including irritable bowel syndrome (IBS) and functional dyspe…
View article: The generic version of China Health Related Outcomes Measures (CHROME-G): psychometric testing and comparative performance with the EQ-5D-5L and SF-6Dv2 among the Chinese general population
The generic version of China Health Related Outcomes Measures (CHROME-G): psychometric testing and comparative performance with the EQ-5D-5L and SF-6Dv2 among the Chinese general population Open
Objectives The CHROME-G is the first generic preference-based measure developed in China. This study aimed to validate and compare the psychometric properties of the CHROME-G with the EQ-5D-5L and SF-6Dv2 among the Chinese general populati…
View article: Asymmetric Z-plasty for correction of iatrogenic nostril “Q” deformities in Asian patients
Asymmetric Z-plasty for correction of iatrogenic nostril “Q” deformities in Asian patients Open
This asymmetric Z-plasty technique, which is a modification of traditional methods, can be used as an effective repair method for iatrogenic nostril "Q" malformation in Asians.
View article: Long‐term clinical outcomes and healthcare resource utilization in male and female patients following hospitalization for heart failure
Long‐term clinical outcomes and healthcare resource utilization in male and female patients following hospitalization for heart failure Open
Aims Heart failure ( HF ) is a leading cause of hospitalization, and sex differences in care have been described. We assessed sex‐specific clinical outcomes and healthcare resource utilization following hospitalization for HF. Methods and …
View article: The role of virtual reality on physical and psychological health among older adults: A systematic review
The role of virtual reality on physical and psychological health among older adults: A systematic review Open
To synthesis and appraise the existing research about the effect and outcomes of virtual reality (VR) interventions among older adults. A systematic review. This systematic review was conducted following the PRISMA guidelines and including…