Lin Feng
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View article: Systematic Review of Small-Molecule Compounds, Analytical Techniques, and Pharmacological Activities of Animal-derived Traditional Chinese Medicines
Systematic Review of Small-Molecule Compounds, Analytical Techniques, and Pharmacological Activities of Animal-derived Traditional Chinese Medicines Open
Animal-derived traditional Chinese medicines (ATCMs), which are prepared from whole animals, organs, or physiological and pathological products, have gained wide recognition and have become an integral part of traditional Chinese medicine …
View article: De novo abnormalities identified by fluorescence in situ hybridization during follow-up confer poor prognosis in Chinese multiple myeloma
De novo abnormalities identified by fluorescence in situ hybridization during follow-up confer poor prognosis in Chinese multiple myeloma Open
Background Although there is evolving consensus to re-evaluate cytogenetic features during follow-up in multiple myeloma (MM), longitudinal studies on cytogenetic evolution in Chinese MM patients are still lacking. Our aim was to highlight…
View article: Improved outcomes in E2A::HLF positive B-cell acute lymphoblastic leukemia by chimeric antigen receptor T cell therapy and BCL-2 inhibitor
Improved outcomes in E2A::HLF positive B-cell acute lymphoblastic leukemia by chimeric antigen receptor T cell therapy and BCL-2 inhibitor Open
To the Editor: The fusion gene E2A::HLF(TCF3::HLF) is formed by t(17;19) (q21-22;p13), which presents in <1% of B-cell acute lymphoblastic leukemia (B-ALL) and mainly occurs in older children and adolescents.[1] Such patients were often ac…
View article: Lactate facilitates classical swine fever virus replication by enhancing cholesterol biosynthesis
Lactate facilitates classical swine fever virus replication by enhancing cholesterol biosynthesis Open
An emerging topic in virology is that viral replication is closely linked with the metabolic reprogramming of host cells. Understanding the effects of reprogramming host cell metabolism due to classical swine fever virus (CSFV) infection a…
View article: Cholesterol Biosynthesis Modulates CSFV Replication
Cholesterol Biosynthesis Modulates CSFV Replication Open
Classical swine fever (CSF) caused by the classical swine fever virus (CSFV) has resulted in severe losses to the pig industry worldwide. It has been proposed that lipid synthesis is essential for viral replication, and lipids are involved…
View article: The anti‑fatigue activities of Tuber melanosporum in a mouse model
The anti‑fatigue activities of Tuber melanosporum in a mouse model Open
Tuber melanosporum (TM) is an edible fungus that exhibits antioxidant and anti-tumor activity via its unique bioactive metabolites. The present study analyzed the anti-fatigue effects of TM using a BALB/c mouse model. The anti-fatigue prop…
View article: [Comparative study of cytogenetic response evaluated by conventional banding analysis and fluorescence in situ hybridization in chronic myeloid leukemia patients during tyrosine kinase inhibitor treatment].
[Comparative study of cytogenetic response evaluated by conventional banding analysis and fluorescence in situ hybridization in chronic myeloid leukemia patients during tyrosine kinase inhibitor treatment]. Open
Objective: To compare the cytogenetic response detected by conventional banding analysis (CBA) and fluorescence in situ hybridization (FISH) and to explore the correlation between the cytogenetic and molecular response in chronic myeloid l…
View article: Anti-Gouty Arthritis and Antihyperuricemia Effects of Sunflower<i> (Helianthus annuus)</i> Head Extract in Gouty and Hyperuricemia Animal Models
Anti-Gouty Arthritis and Antihyperuricemia Effects of Sunflower<i> (Helianthus annuus)</i> Head Extract in Gouty and Hyperuricemia Animal Models Open
This study was performed to investigate the therapeutic effects and possible mechanisms of sunflower (Helianthus annuus) head extract (SHE) on gout. First, the components of sunflower head powder and SHE were analyzed systematically. SHE, …