Explanipedia

Evaluation of risk factors for acute stroke using combined CTA and MR HR-VWI imaging Open

Lin Chen, Qian Guo, Jianping Zhao, Haihua Bao, Fanrong Meng , et al. · 2025

Objective To investigate the correlation between the changes of peripheral carotid fat density (PFD), the occurrence of acute cerebral ischemia events and the characteristics of different dangerous plaques. Methods A retrospective analysis…

Comprehensive analysis of m6A-related lncRNAs as prognosis factors in the immune microenvironment of colorectal cancer Open

Tian Lan, Wei Li, Fei Xu, Fanrong Meng, Xing Zhang , et al. · 2025

This study constructed an mRLs risk model that effectively predicts CRC prognosis and immune profiles, offering a potential tool for personalized therapeutic decision-making.

Risk of intraoperative hemorrhage during cesarean scar ectopic pregnancy surgery: development and validation of an interpretable machine learning prediction model Open

Chen Xin-li, Huan Zhang, Dong Guo, Siyuan Yang, Bao Liu , et al. · 2024

TaMIR397-6A and -6B Homoeologs Encode Active miR397 Contributing to the Regulation of Grain Size in Hexaploid Wheat Open

Putong Wang, Yujie Wu, Junhui Zhang, Jiao Si, Xiaoteng Wang , et al. · 2024

Wheat is one of the most important food crops globally, and understanding the regulation of grain size is crucial for wheat breeding to achieve a higher grain yield. MicroRNAs (miRNAs) play vital roles in plant growth and development. Howe…

Evaluation of Cyperus Fertility Improvement in Aeolian Soils from an Application of Humic Acid Combined with Compound Fertilizer Open

Jianfa Yan, Xianmei Zhang, Fanrong Meng, Guodong Chen, Ruodi Wang , et al. · 2023

Humic acid is a macromolecular organic compound with active groups that, when applied to the soil, can regulate the storage and release of nutrient elements. The effects of a humic acid application at two application rates (F-1: 15 t·hm−2 …

Correction: Wilms’ tumour gene 1 (WT1) enhances non-small cell lung cancer malignancy and is inhibited by microRNA-498-5p Open

Xuebing Li, Wenzhe An, Hongli Pan, Yaguang Fan, Hua Huang , et al. · 2023

Wilms’ tumour gene 1 (WT1) enhances non-small cell lung cancer malignancy and is inhibited by microRNA-498-5p Open

Xuebing Li, Wenzhe An, Hongli Pan, Yaguang Fan, Hua Huang , et al. · 2023

Background Wilms’ tumour gene 1 (WT1) is clearly recognized as a tumour promoter in diversiform of human malignancies. Nevertheless, knowledge of its expression, functions and potential molecular mechanisms in non-small cell lung cancer (N…

Establishment and characterization of a novel highly malignant lung cancer cell line <span>ZX2021H</span> derived from a metastatic lymph node lesion Open

Lingling Zu, Xuebing Li, Jinling He, Ning Zhou, Fanrong Meng , et al. · 2022

Background Lung cancer is a highly malignant tumor with a poor prognosis. The establishment of faithful ex vivo cell models is essential for investigating the metastatic mechanisms and developing new anticancer agents. In this study, we es…

MicroRNA-1915-3p inhibits cell migration and invasion by targeting SET in non-small-cell lung cancer Open

Hongli Pan, Zhenhua Pan, Fengjie Guo, Fanrong Meng, Lingling Zu , et al. · 2021

Identification of hsa-miR-1275 as a Novel Biomarker Targeting MECP2 for Human Epilepsy of Unknown Etiology Open

Ye Zhao, Congxia Lu, Huiling Wang, Qing Lin, Liangliang Cai , et al. · 2020

Differential expression of microRNA-411 and 376c is associated with hypertension in pregnancy Open

Huili Yang, Zhang Hong-zhi, Fanrong Meng, Shuyi Han, Miao Zhang · 2019

Preeclampsia is a major reason of morbidity and mortality in pregnant women and perinatal fetus. Hence, it is of prime importance that diagnostic markers are defined to predict chances of preeclampsia in pregnant women. It has been previou…

Differential expression of microRNA-411 and 376c is associated with hypertension in pregnancy Open

Huili Yang, Zhang Hong-zhi, Fanrong Meng, Shuyi Han, Miao Zhang · 2019

Preeclampsia is a major reason of morbidity and mortality in pregnant women and perinatal fetus. Hence, it is of prime importance that diagnostic markers are defined to predict chances of preeclampsia in pregnant women. It has been previou…

A Resource for Inactivation of MicroRNAs Using Short Tandem Target Mimic Technology in Model and Crop Plants Open

Ting Peng, Mengmeng Qiao, Haiping Liu, Sachin Teotia, Zhan‐Hui Zhang , et al. · 2018

[Construction of EZH2 Knockout Animal Model by CRISPR/Cas9 Technology]. Open

Fanrong Meng, Dan Zhao, Qinghua Zhou, Zhe Liu · 2018

The study successfully designed two sgRNA which can play a knock-out EZH2 function. An EZH2 knockout animal model was successfully constructed by CRISPR/Cas9 system, and it will be an effective animal model for studying the functions and m…

Downregulation of PRDM1 promotes cellular invasion and lung cancer metastasis Open

Zhiyan Zhu, Hao Wang, Yi‐Liang Wei, Fanrong Meng, Zhe Liu , et al. · 2017

The zinc-finger transcription factor PRDM1 (PR domain containing 1) plays key roles in the development of malignant lymphoma, leukaemia and some non-haematopoietic cancers, including breast cancer, colorectal cancer and glioma. However, li…

[Diagnostic and treatment cost of invasive fungal infections in patients with hematologic malignancies during hospitalization]. Open

Yong Ji, Yu‐Qian Sun, He Huang, Jie Chen, Xi Zhang , et al. · 2016

Efficient targeted mutagenesis in potato by the CRISPR/Cas9 system Open

Shaohui Wang, Shuaibin Zhang, Wanxing Wang, Xingyao Xiong, Fanrong Meng , et al. · 2015

[Interaction between microRNAs and OCT4]. Open

Chen Chen, Fanrong Meng, Haisu Wan, Qinghua Zhou · 2015

Octamer-binding transcription factor 4 (OCT4) belongs to the POU-homeodomain family of transcription factors and binds to an octamer motif, ATGCAAAT. OCT4 is the key transcription factor that is involved in the maintenance of pluripotency …

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