Fariba Karimzadeh
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View article: The role of high-density lipoprotein and Vitamin D in exercise-induced neuroprotection in epileptic rats
The role of high-density lipoprotein and Vitamin D in exercise-induced neuroprotection in epileptic rats Open
Previous studies have reported the neuroprotective effects of exercise in epilepsy. Hence, this study aimed to investigate the potential mechanisms underlying these neuroprotective effects by examining changes in high-density lipoprotein (…
View article: Growth‐Associated Protein 43 Levels in the Cerebrospinal Fluid Correspond to the Cerebral Blood Flow Alterations in Alzheimer's Dementia Continuum: An Original Study
Growth‐Associated Protein 43 Levels in the Cerebrospinal Fluid Correspond to the Cerebral Blood Flow Alterations in Alzheimer's Dementia Continuum: An Original Study Open
Background and Aims Alzheimer's disease (AD) is a widespread neurodegenerative condition that has a growing impact on a global scale. This study aims to examine the relationship between cerebral blood flow (CBF) and the synaptic biomarker …
View article: Retraction Note: Serum melatonin levels and in a sample of Iranian patients with migraine
Retraction Note: Serum melatonin levels and in a sample of Iranian patients with migraine Open
View article: The Effect of Physical Activity on the Orexin and Brain-derived Neurotrophic Factor Expression on the Kindling Model of Epileptic Rats
The Effect of Physical Activity on the Orexin and Brain-derived Neurotrophic Factor Expression on the Kindling Model of Epileptic Rats Open
Our results indicate that PA had an amelioration effect on the severity of the seizure. Our findings suggest that the effect of PA on seizure might not arise from the interaction of the OXA and BDNF expression in epileptic rats.
View article: RETRACTED ARTICLE: Serum melatonin levels and in a sample of Iranian patients with migraine
RETRACTED ARTICLE: Serum melatonin levels and in a sample of Iranian patients with migraine Open
Migraine, a complex disorder, is characterized by recurrent headache episodes. The production of melatonin in the pineal gland, which is crucial for controlling circadian rhythms and sleep-wake cycles, is altered in various conditions, inc…
View article: The Modulatory Effect of Exercise on the Endocannabinoid Signaling Pathway in the Epileptic Rats
The Modulatory Effect of Exercise on the Endocannabinoid Signaling Pathway in the Epileptic Rats Open
Background: Regular moderate exercise and endogenous cannabinoid activity have independently been shown to alleviate seizure (SE) attacks. Objectives: This study aimed to investigate the effect of physical activity on the expression levels…
View article: Retraction Note: Developmental changes in Notch1 and NLE1 expression in a genetic model of absence epilepsy
Retraction Note: Developmental changes in Notch1 and NLE1 expression in a genetic model of absence epilepsy Open
View article: CURCUMIN PREVENTS ACCELERATION OF KINDLING EPILEPTOGENESIS INDUCED BY TRAUMATIC BRAIN INJURY
CURCUMIN PREVENTS ACCELERATION OF KINDLING EPILEPTOGENESIS INDUCED BY TRAUMATIC BRAIN INJURY Open
View article: Daily Oral Memantine Attenuated the Severity of Borderline Personality Disorder Symptoms: A Double-Blind Placebo-Controlled, Randomized Clinical Trial
Daily Oral Memantine Attenuated the Severity of Borderline Personality Disorder Symptoms: A Double-Blind Placebo-Controlled, Randomized Clinical Trial Open
Background: Borderline personality disorder (BPD) has been considered a psychiatric disorder, the effective pharmacological treatments for which have not been well established. Objectives: This study aimed to assess the efficacy of memanti…
View article: High and Low-Frequency Stimulation Effect on Epileptiform Activity in Brain Slices
High and Low-Frequency Stimulation Effect on Epileptiform Activity in Brain Slices Open
Neurostimulation techniques consisting of LFS and HFS have a potential role in treating epileptiform activity, with some studies having positive results. Further investigations with larger sample sizes and standardized outcome measures can…
View article: Modulatory Effect of Neurotrophic Factors on the TRPV1 Expression: Possible Mechanisms Involved in the Antiepileptic Effect of Exercise
Modulatory Effect of Neurotrophic Factors on the TRPV1 Expression: Possible Mechanisms Involved in the Antiepileptic Effect of Exercise Open
Background: Epilepsy is one of the most important diseases of the central nervous system, for which has no definitive treatment. Neurotrophic factors increase the survival of nerve cells and improve the treatment of neurological diseases. …
View article: C-Met Receptors Deficiency Was Involved in Absence Seizures Development in WAG/Rij Rats
C-Met Receptors Deficiency Was Involved in Absence Seizures Development in WAG/Rij Rats Open
Background: A variety of receptors may be involved in the pathogenesis of absence seizures. The c-Met receptors have a critical role in modulating the GABAergic interneurons and creating a balance between excitatory and inhibitory neurotra…
View article: A Narrative Review of the Role of Orexin in the Epileptogenesis
A Narrative Review of the Role of Orexin in the Epileptogenesis Open
Introduction:Epilepsy is a neurological disorder characterized by seizures and affects about 65-70 million people worldwide.Many pathways and molecules are altered in the epilepsy process that can be used as targets in the treatment of epi…
View article: Evaluating Plasma and Brain TRPV1 Channels in the Animal Model of Episodic and Chronic Migraine: The Possible Role of Somatosensory Cortex TRPV1 in Migraine Transformation
Evaluating Plasma and Brain TRPV1 Channels in the Animal Model of Episodic and Chronic Migraine: The Possible Role of Somatosensory Cortex TRPV1 in Migraine Transformation Open
Background: Despite extensive research, the exact molecular mechanisms underlying migraine development and especially its progression and transformation from episodic into chronic is still unknown. Objectives: This study aimed to assess th…
View article: Evaluation of Serum Levels of Transient Receptor Potential Cation Channel Subfamily V Member 1, Vasoactive Intestinal Polypeptide, and Pituitary Adenylate Cyclase-Activating Polypeptide in Chronic and Episodic Migraine: The Possible Role in Migraine Transformation
Evaluation of Serum Levels of Transient Receptor Potential Cation Channel Subfamily V Member 1, Vasoactive Intestinal Polypeptide, and Pituitary Adenylate Cyclase-Activating Polypeptide in Chronic and Episodic Migraine: The Possible Role in Migraine Transformation Open
Objectives: This study aimed to investigate the role of serum levels of transient receptor potential cation channel subfamily V member 1 (TRPV1), vasoacive intestinal peptide (VIP), and pituitary adenylate cyclase-activating polypeptide (P…
View article: A Review on the Experimental Animal Models of Cerebral Ischemia
A Review on the Experimental Animal Models of Cerebral Ischemia Open
View article: The Role of Astrocytes in the Central Nervous System: Physiological and Pathophysiological Conditions
The Role of Astrocytes in the Central Nervous System: Physiological and Pathophysiological Conditions Open
The Role of Astrocytes in the Central Nervous System: Physiological and Pathophysiological Conditions
View article: COVID-19 and Alzheimer's Disease: A Review of Mechanisms and Pathophysiology
COVID-19 and Alzheimer's Disease: A Review of Mechanisms and Pathophysiology Open
View article: Experimental Models of Absence Epilepsy
Experimental Models of Absence Epilepsy Open
Introduction: Absence epilepsy is a brief non-convulsive seizure associated with sudden abruptness in consciousness. Because of the unpredictable occurrence of absence seizures and the ethical issues of human investigation on the pathogene…
View article: The Effect of SARS-COV-2 Viruses on the Function of Different Organs, Especially the Nervous System
The Effect of SARS-COV-2 Viruses on the Function of Different Organs, Especially the Nervous System Open
Introduction:The new coronavirus (SARS-CoV-2) has recently emerged around the world as a pandemic.The disease has various symptoms such as cough, dyspnea, and fever.The disease causes failure in different organs, including the respiratory,…
View article: The Effect of Vitamins B on Improving the Symptoms of Migraine: An Overview
The Effect of Vitamins B on Improving the Symptoms of Migraine: An Overview Open
View article: Glutamate Signaling Pathway in Absence Epilepsy: Possible Role of Ionotropic AMPA Glutamate Receptor Type 1 Subunit.
Glutamate Signaling Pathway in Absence Epilepsy: Possible Role of Ionotropic AMPA Glutamate Receptor Type 1 Subunit. Open
AMPA receptors, consisting of glutamate receptor type1 (GluR1) subunit are involved in the pathophysiology of some neurological disorders. In this study, the role of the GluR1 subunit in the development, as well as features of absence seiz…
View article: Experimental Models of Absence Epilepsy: A Review Article
Experimental Models of Absence Epilepsy: A Review Article Open
Introduction: Absence epilepsy is a brief non-convulsive seizure associated with sudden abruptness in consciousness.Because of the unpredictable occurrence of absence seizures and the ethical issues of human investigation on the pathogenes…
View article: The organizational culture of Iran University of Medical Sciences from the viewpoint of faculty members
The organizational culture of Iran University of Medical Sciences from the viewpoint of faculty members Open
The organizational culture of Iran University of Medical Sciences from the viewpoint of faculty members
View article: The organizational culture of Iran University of Medical Sciences from the viewpoint of faculty members.
The organizational culture of Iran University of Medical Sciences from the viewpoint of faculty members. Open
Background: It has been widely acknowledged that change and constant modification is the key to survive for any organization among their rivals. Since success in implementing changes in the organization strongly depends on the organ…
View article: A Review on the Structural and Metabolic Biomarkers in Migraine
A Review on the Structural and Metabolic Biomarkers in Migraine Open
Introduction:Migraine is a neurovascular illness with repeated attacks of modes t to intense headache, las ting 4-72 hours and linked to nausea, vomiting, and sensitivity to light and noise.Migraine is often associated with as thma, anxiet…
View article: The Effects of Exercise Training Intensity on the Expression of C/EBPβ and CITED4 in Rats with Myocardial Infarction
The Effects of Exercise Training Intensity on the Expression of C/EBPβ and CITED4 in Rats with Myocardial Infarction Open
Background: Exercise training (ET) has a cardioprotective effect and can induce new cardiomyocyte formation in physiological cardiac remodeling. However, following a large myocardial infarction (MI), the changes in cardiac regeneration and…
View article: A review on the animal models of seizure: review article
A review on the animal models of seizure: review article Open
Nowadays, there are various animal models of acute and chronic seizures. Some chemical and electrical models such as seizure induced by pentylenetetrazol injection and maximum electric shock has been developed over of six decades and diffe…
View article: Stable Knockdown of Adenosine Kinase by Lentiviral Anti-ADK miR-shRNAs in Wharton's Jelly Stem Cells.
Stable Knockdown of Adenosine Kinase by Lentiviral Anti-ADK miR-shRNAs in Wharton's Jelly Stem Cells. Open
Our findings indicate efficient usage of shRNA cassette for ADK knockdown. Engineered WJMSCs with genome editing methods like CRISPR/cas9 or more safe viral systems such as adeno-associated vectors (AAV) might be an attractive source in ce…
View article: Structural and Metabolic Biomarkers in Multiple Sclerosis
Structural and Metabolic Biomarkers in Multiple Sclerosis Open
Introduction: Multiple Sclerosis (MS) is a chronic progressive course of illness that leads to the widespread pathological processes of neurodegeneration, including neuroaxonal damage, apoptosis and gliosis. Due to complex mechanisms invol…