Farina Josepha Strüwe
YOU?
Author Swipe
View article: Unmet Supportive Care Needs in Adults With Li–Fraumeni Syndrome: A Mixed‐Methods Study
Unmet Supportive Care Needs in Adults With Li–Fraumeni Syndrome: A Mixed‐Methods Study Open
Introduction: Individuals with Li–Fraumeni syndrome (LFS) face an increased risk for multiple cancers. LFS is caused by pathogenic variants in the TP53 gene and individuals with LFS are recommended intense cancer surveillance programs to i…
View article: Health‐related quality of life and fear of progression in individuals with <scp>Li‐Fraumeni</scp> syndrome
Health‐related quality of life and fear of progression in individuals with <span>Li‐Fraumeni</span> syndrome Open
Li‐Fraumeni syndrome (LFS) is a rare autosomal dominant cancer predisposition syndrome associated with a highly elevated lifetime cancer risk. This and the recommended intense surveillance program represent a large psychological burden on …
View article: Research on Rare Diseases in Germany - Cancer Predisposition Syndrome Registry
Research on Rare Diseases in Germany - Cancer Predisposition Syndrome Registry Open
The CPS registry is an example of how progress can be made within a short period of time to the benefit of individuals with rare diseases through systematic data collection and research.
View article: <i>RUNX1</i> isoform disequilibrium promotes the development of trisomy 21–associated myeloid leukemia
<i>RUNX1</i> isoform disequilibrium promotes the development of trisomy 21–associated myeloid leukemia Open
Gain of chromosome 21 (Hsa21) is among the most frequent aneuploidies in leukemia. However, it remains unclear how partial or complete amplifications of Hsa21 promote leukemogenesis and why children with Down syndrome (DS) (ie, trisomy 21)…
View article: <i>RUNX1</i> isoform disequilibrium in the development of trisomy 21 associated myeloid leukemia
<i>RUNX1</i> isoform disequilibrium in the development of trisomy 21 associated myeloid leukemia Open
Aneuploidy is a hallmark of cancer, but its complex nature limits our understanding of how it drives oncogenesis. Gain of chromosome 21 (Hsa21) is among the most frequent aneuploidies in leukemia and is associated with markedly increased l…