Farshad Abedi
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View article: A Case Report of Erythema Nodosum Following Letrozole Administration in a 44-Year-Old Iranian Female Patient with Breast Cancer
A Case Report of Erythema Nodosum Following Letrozole Administration in a 44-Year-Old Iranian Female Patient with Breast Cancer Open
Letrozole, a nonsteroidal aromatase inhibitor, is the adjuvant endocrine treatment for postmenopausal women with estrogen receptor-positive breast cancer. Erythema nodosum (EN) is a rare skin adverse effect of letrozole which has been prev…
View article: Renal manifestations of brucellosis: a case report
Renal manifestations of brucellosis: a case report Open
Our case highlights the importance of considering brucellosis as a potential cause of pyelonephritis, especially where brucellosis is endemic and when musculoskeletal involvement is present. Additionally, a comprehensive review of the lite…
View article: The effect of atorvastatin topical solution on preventing peritoneal adhesion in rats
The effect of atorvastatin topical solution on preventing peritoneal adhesion in rats Open
Background: Peritoneal adhesion is a critical postsurgical complication in abdominal and pelvic surgeries. Due to their antiinflammatory and fibrinolytic properties, statins are assumed to reduce peritoneal adhesions effectively. Our study…
View article: A Systematic Review of Oxidative Stress Markers and Risk of Coronary Artery Calcification
A Systematic Review of Oxidative Stress Markers and Risk of Coronary Artery Calcification Open
Background: Early diagnosis of atherosclerosis, particularly in its subclinical phase, is crucial for reducing mortality and morbidity associated with cardiovascular diseases. This study aims to investigate the relationship between oxidati…
View article: Exploring Hydrogel Nanoparticle Systems for Enhanced Ocular Drug Delivery
Exploring Hydrogel Nanoparticle Systems for Enhanced Ocular Drug Delivery Open
Drug delivery to the ocular system is affected by anatomical factors like the corneal epithelium, blinking reflex, aqueous blood barrier, and retinal blood barrier, which lead to quick removal from the site and inefficient drug delivery. D…
View article: HDL-cholesterol concentration and its association with coronary artery calcification: a systematic review and meta-analysis
HDL-cholesterol concentration and its association with coronary artery calcification: a systematic review and meta-analysis Open
Background Coronary artery calcification (CAC) is a potential risk marker of coronary atherosclerosis that has high specificity and sensitivity. However, the association between high-density lipoprotein cholesterol (HDL-C) concentration an…
View article: Pharmacological Approach for Prevention of Bleomycin-Induced Lung Injury
Pharmacological Approach for Prevention of Bleomycin-Induced Lung Injury Open
Bleomycin is a chemotherapeutic medication commonly use in the treatment of Hodgkin's disease and germ cell tumors. Pulmonary fibrosis is major and dose limiting adverse effect of the drug. There is not currently any equal alternative appr…
View article: Supplemental Preparations in Taxane-Induced Neuropathy Management
Supplemental Preparations in Taxane-Induced Neuropathy Management Open
Taxane-induced peripheral neuropathy (TIPN) is a dose-limiting adverse effect of chemotherapy without any specific treatment. The aim of this paper is to evaluate the effects of natural products and supplements on TIPN. PubMed, Google Scho…
View article: Mustard Gas–Induced Ocular Surface Disorders: An Update on the Pathogenesis, Clinical Manifestations, and Management
Mustard Gas–Induced Ocular Surface Disorders: An Update on the Pathogenesis, Clinical Manifestations, and Management Open
Purpose: Mustard gas (MG) is a potent blistering and alkylating agent that has been used for military and terrorism purposes. Ocular surface injuries are common after exposure to MG. This review provides an update on the pathophysiology, o…
View article: Evaluation of the effect of crocin on prevention of atrial fibrillation after coronary artery bypass grafting or heart valve replacement: A double-blind, randomized, placebo-controlled trial.
Evaluation of the effect of crocin on prevention of atrial fibrillation after coronary artery bypass grafting or heart valve replacement: A double-blind, randomized, placebo-controlled trial. Open
It seems that prophylactic use of crocin is effective in reducing the incidence of POAF in patients undergoing heart surgeries.
View article: The Effect of Heparin and Its Preparations on Disseminated Intravascular Coagulation Mortality and Hospitalization: A Systematic Review
The Effect of Heparin and Its Preparations on Disseminated Intravascular Coagulation Mortality and Hospitalization: A Systematic Review Open
Background and Aim . Disseminated intravascular coagulation (DIC) is a critical clinical condition that is expressed by systemic activation of the homeostatic system, leading to elevation of thrombin deposition and result in microvascular …
View article: Alterations in corneal nerves in different subtypes of dry eye disease: An in vivo confocal microscopy study
Alterations in corneal nerves in different subtypes of dry eye disease: An in vivo confocal microscopy study Open
View article: Nephroprotective activity of natural products against chemical toxicants: The role of Nrf2/ARE signaling pathway
Nephroprotective activity of natural products against chemical toxicants: The role of Nrf2/ARE signaling pathway Open
Nephropathy can occur following exposure of the kidneys to oxidative stress. Oxidative stress is the result of reactive oxygen species (ROS) formation due to intracellular catabolism or exogenous toxicant exposure. Many natural products (N…
View article: MicroRNAs and SARS-CoV-2 life cycle, pathogenesis, and mutations: biomarkers or therapeutic agents?
MicroRNAs and SARS-CoV-2 life cycle, pathogenesis, and mutations: biomarkers or therapeutic agents? Open
To date, proposed therapies and antiviral drugs have been failed to cure coronavirus disease 2019 (COVID-19) patients. However, at least two drug companies have applied for emergency use authorization with the United States Food and Drug A…
View article: Plausibility of therapeutic effects of Rho kinase inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (COVID-19)
Plausibility of therapeutic effects of Rho kinase inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (COVID-19) Open
View article: Comparision of Aqueous and Hydroalcoholic Extracts of Foeniculum Vulgare and Carum Copticum with Gentamicin on Escherichia Coli Strains: in Vitro Study
Comparision of Aqueous and Hydroalcoholic Extracts of Foeniculum Vulgare and Carum Copticum with Gentamicin on Escherichia Coli Strains: in Vitro Study Open
BACKGROUND AND OBJECTIVE: Due to bacterial resistance to antibiotics, new antibacterial agents is essential. In Persian medicine Fennel (Fuenoculum vulgare Mill.) and Ajwain (Carum copticum (L.) Benth. & Hook.f.) are recommended for the tr…