Fatemeh Madani
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View article: Biophysical characterization of glatiramer acetate (Copaxone): membrane model interactions, vesicle leakage, and secondary structure effects
Biophysical characterization of glatiramer acetate (Copaxone): membrane model interactions, vesicle leakage, and secondary structure effects Open
The synthetic copolymer glatiramer acetate (GA), commercially known as Copaxone, was developed in the 1990s as a treatment for relapsing multiple sclerosis (MS). Recent studies suggest that GA may also exhibit antimicrobial activity. Despi…
View article: Exploring Cuscuta epithymum's effect on neuroinflammation, tyrosine kinase activity and macrophage counts in spleen and liver: revealing their roles in stress responses
Exploring Cuscuta epithymum's effect on neuroinflammation, tyrosine kinase activity and macrophage counts in spleen and liver: revealing their roles in stress responses Open
Purpose: Chronic stress usually causes immunosuppression, activates tyrosine kinase (TK), and increases inflammatory responses. Based on Persian medicine, the spleen is crucial for the immune system and stress response. Cuscuta epithymum (…
View article: Effect of 8-Week- - Concurrent Training and Capsaicin Supplementation on the Expression of IGF-1 and FOXO3 Genes in the Quadriceps Muscle of Aged Male Wistar Rats
Effect of 8-Week- - Concurrent Training and Capsaicin Supplementation on the Expression of IGF-1 and FOXO3 Genes in the Quadriceps Muscle of Aged Male Wistar Rats Open
Introduction: Aging is a gradual and progressive process accompanied by fundamental changes in the structure of skeletal muscles. These alternations include decreased muscle mass and strength, leading to serious challenges in the lives of …
View article: Combination chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood–brain–barrier in a glioblastoma model
Combination chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood–brain–barrier in a glioblastoma model Open
The effect of chemotherapy for anti-glioblastoma is limited due to insufficient drug delivery across the blood-brain-barrier. Poloxamer 188-coated nanoparticles can enhance the delivery of nanoparticles across the blood-brain-barrier. This…
View article: Combinatorial chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood-brain-barrier in a glioblastoma model
Combinatorial chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood-brain-barrier in a glioblastoma model Open
The effect of anti-glioblastoma therapies is dwindling due to insufficient delivery across the blood-brain-barrier. It has been stated that poloxamer 188-coated nanoparticles are able to circumvent the blood-brain-barrier. Building off of …
View article: The Effect of 8 Weeks of Aerobic Exercise Along with Nano-Curcumin on the Expression of Atrogin-1 and Murf-1 Genes in Soleus Muscle of Male Wistar Rat: A Short Report
The Effect of 8 Weeks of Aerobic Exercise Along with Nano-Curcumin on the Expression of Atrogin-1 and Murf-1 Genes in Soleus Muscle of Male Wistar Rat: A Short Report Open
The Effect of 8 Weeks of Aerobic Exercise Along with Nano-Curcumin on the Expression of Atrogin-1 and Murf-1 Genes in Soleus Muscle of Male Wistar Rat: A Short Report
View article: PLGA Nanoparticles Loaded with Cinnamon Extract and Coated with PVA/Poloxamer188
PLGA Nanoparticles Loaded with Cinnamon Extract and Coated with PVA/Poloxamer188 Open
Cinnamon extract has received significant attention due to its significant antibacterial, antifungal, antioxidant, and even anti-cancer properties. The purpose of this study was to create cinnamon-extract-loaded PLGA nanoparticles and eval…
View article: 5-Fluorouracil-induced toxicity in both male and female reproductive systems: A narrative review
5-Fluorouracil-induced toxicity in both male and female reproductive systems: A narrative review Open
The chemotherapeutic drug 5-fluorouracil (5FU) is frequently used to treat a wide range of solid malignant tumors, such as colorectal, pancreatic, gastric, breast, and head and neck cancers. Its antitumoral effects are achieved by interfer…
View article: Experimental study of energy absorption in 3D-textile reinforced polymer composites under high-velocity impact loading
Experimental study of energy absorption in 3D-textile reinforced polymer composites under high-velocity impact loading Open
In this paper, the energy absorption capacity of polymer composites reinforced with Kevlar fibers and various textile structures under high-velocity impact loading was investigated. Noobing textile, woven laminate, and stitched laminate we…
View article: Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation
Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation Open
View article: Investigation of Effective Parameters on Size of Paclitaxel Loaded PLGA Nanoparticles
Investigation of Effective Parameters on Size of Paclitaxel Loaded PLGA Nanoparticles Open
Purpose: The size of polymeric nanoparticles is considered as an effective factor in cancer therapy due to enterance into tumor tissue via the EPR effect. The purpose of this work was to investigate the effective parameters o…
View article: Preparation of Methotrexate loaded PLGA nanoparticles coated with PVA and Poloxamer188
Preparation of Methotrexate loaded PLGA nanoparticles coated with PVA and Poloxamer188 Open
Objective(s): Nanoparticles offer an attractive platform for drug delivery through a wide variety of the body's physiological barriers. Furthermore, modification of nanoparticle surface with moeites such as Poloxamer188 ca…
View article: Landslide hazard Zonation by using Fuzzy MCDM Models In the GIS (Case Study: Izeh Urban Watersheds of Khuzestan)
Landslide hazard Zonation by using Fuzzy MCDM Models In the GIS (Case Study: Izeh Urban Watersheds of Khuzestan) Open
Landslide hazard Zonation by using Fuzzy MCDM Models In the GIS (Case Study: Izeh Urban Watersheds of Khuzestan)