FB Abdulkareem
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View article: Circulating cell‐free <scp>DNA</scp> methylation biomarkers for hepatocellular carcinoma risk prediction in <scp>HIV</scp> ‐positive Nigerian population
Circulating cell‐free <span>DNA</span> methylation biomarkers for hepatocellular carcinoma risk prediction in <span>HIV</span> ‐positive Nigerian population Open
Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality globally, with particularly high burdens among people living with HIV (PLWH) in low‐resource settings like Nigeria. Effective early detection remains a major challenge d…
View article: Changing Trends in Appendiceal Pathology: A 16-Year Retrospective Extension Study of Surgically Removed Appendices in a Tropical Teaching Hospital
Changing Trends in Appendiceal Pathology: A 16-Year Retrospective Extension Study of Surgically Removed Appendices in a Tropical Teaching Hospital Open
Background:The vermiform appendix is prone to various diseases, with acute appendicitis (AA) being the most common. The increasing incidence in Nigeria complicates diagnosis, leading to negative appendectomies. Accurate and timely diagnosi…
View article: The Pharmacists' Role in Reducing Drug-Related Problems in Cardiology Center in Baghdad -Iraq: A Pilot Study
The Pharmacists' Role in Reducing Drug-Related Problems in Cardiology Center in Baghdad -Iraq: A Pilot Study Open
Pharmacotherapy is essential to lower the morbidity and mortality associated with cardiovascular diseases. Patients with cardiovascular (CV) disease are often given polypharmacy which increases both the incidence of errors in prescriptions…
View article: Immunohistochemistry Expression of Programmed Death-Ligand 1 in Colorectal Carcinoma among Nigerians
Immunohistochemistry Expression of Programmed Death-Ligand 1 in Colorectal Carcinoma among Nigerians Open
Background: Colorectal carcinoma (CRC) is the most common gastrointestinal malignancy in Nigeria with a dismal 5-year survival rate. Interactions between the CD8+ T-lymphocytes and the immune checkpoints such as cytotoxic T-lymphocyte anti…
View article: Advanced trauma life support training outcomes in Saudi Arabia: a four-year multicenter analysis of influential characteristics and factors (2019-2023)
Advanced trauma life support training outcomes in Saudi Arabia: a four-year multicenter analysis of influential characteristics and factors (2019-2023) Open
BACKGROUND: The prevalence of trauma necessitates effective training for healthcare providers in Saudi Arabia. The Advanced Trauma Life Support (ATLS) program is pivotal, yet localized success rate data are lacking. OBJECTIVES: Determine t…
View article: The impact of a communal multidisciplinary tumour board on medical education
The impact of a communal multidisciplinary tumour board on medical education Open
The tumour board/network improved the outcome of musculoskeletal tumours over the study period. The network improved the education of medical doctors and increased the capacity for training newer instructors in a resource-limited environme…
View article: Hepatitis B and C Virus Co-Infection and Their Association With Liver Disease in Persons With HIV in Nigeria
Hepatitis B and C Virus Co-Infection and Their Association With Liver Disease in Persons With HIV in Nigeria Open
Background: The burden of chronic viral hepatitis among people living with human immunodeficiency virus (PLWH) and its association with liver disease in Nigeria has been seldom explored. Our objective was to compare characteristics in PLWH…
View article: The African Research Group for Oncology: A decade fostering colorectal cancer research in Nigeria
The African Research Group for Oncology: A decade fostering colorectal cancer research in Nigeria Open
The African Research Group for Oncology (ARGO) was formed in 2013 to undertake methodologically rigorous cancer research in Nigeria, and to strengthen cancer research capacity in the country through training and mentorship of physicians, s…
View article: Annona senegalensis stem bark extracts attenuated doxorubicin-induced hepatotoxicity and mitochondrial oxidative damage in Wistar strain albino rats
Annona senegalensis stem bark extracts attenuated doxorubicin-induced hepatotoxicity and mitochondrial oxidative damage in Wistar strain albino rats Open
Background and Objective: Doxorubicin (DOX)- an anthracycline is a well-known anticancer agent but its limitation lies in it hepato- and cardio-toxicity involving the mitochondrial redox pathway. Thus, there is need for chemoprotective age…
View article: Inherent Occupational Health Assessment for Alternative Hydrogen Synthesis Pathways
Inherent Occupational Health Assessment for Alternative Hydrogen Synthesis Pathways Open
Hydrogen is one of the most investigated topics in energy transition due to its sustainability and vast applicability. However, it has health and safety challenges like any other chemical process. Most attention focuses on this fuel produc…
View article: Soghin clinical practice guidelines for hepatocellular carcinoma
Soghin clinical practice guidelines for hepatocellular carcinoma Open
HCC accounts for over 90% of primary liver cancers and 7% of all cancers from all sites worldwide. In Nigeria, HCC develops at a younger age compared to the developed world and co-exists with liver cirrhosis in about 80% of cases. The prog…
View article: Concurrent Sarcina ventriculi infection in a patient with Helicobacter pylori-associated chronic gastritis: A case report
Concurrent Sarcina ventriculi infection in a patient with Helicobacter pylori-associated chronic gastritis: A case report Open
Sarcina ventriculi is a Gram-positive, nonmotile, chemo-organotrophic anaerobic organism, which is rare in humans. Although its role as a pathogen in humans remains poorly characterized, it has been associated with delayed gastric emptying…
View article: High Isoniazid Preventive Therapy Completion Rate among Household Contacts of Tuberculosis Patients in Duhok Province
High Isoniazid Preventive Therapy Completion Rate among Household Contacts of Tuberculosis Patients in Duhok Province Open
Background And Objective: Tuberculosis (TB) preventive therapy is a key intervention to achieve a world free of TB.We assessed the completion rate of isoniazid preventive therapy (IPT) among household contacts (HHCs) in Duhok province.Meth…
View article: Preputial Cyst in the Newborn
Preputial Cyst in the Newborn Open
Cysts of the prepuce are rare, and documented reports from the English literature are mostly from Asia. Presentations in children are worrisome to the parents. We report a case of a preputial cyst occurring in a neonate who was brought to …
View article: Cervical Epithelial Abnormalities and Associated Factors among HIV-Infected Women in Lagos, Nigeria: A Cytology-Based Study
Cervical Epithelial Abnormalities and Associated Factors among HIV-Infected Women in Lagos, Nigeria: A Cytology-Based Study Open
Introduction: As it may not be feasible to provide cervical cancer screening services to all HIV-infected women in most resource-limited settings, there is a need to identify those who are most at risk. We determined the prevalence, patter…
View article: Clinicopathological Features, Risk Profile Assessment, and the Surgical Outcome of Gastrointestinal Stromal Tumors in Lagos, Nigeria
Clinicopathological Features, Risk Profile Assessment, and the Surgical Outcome of Gastrointestinal Stromal Tumors in Lagos, Nigeria Open
Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. GISTs originate from the interstitial cells of Cajal and are most commonly found in the stomach. Most available repor…
View article: Flavonoid and Organosulphur Phytoconstituents From Allium Sativum Inhibits Antiapoptotic Protein Bcl-2: A Computational Molecular Modeling Study
Flavonoid and Organosulphur Phytoconstituents From Allium Sativum Inhibits Antiapoptotic Protein Bcl-2: A Computational Molecular Modeling Study Open
PURPOSE Apoptosis resistance to anticancer treatments can occur due to over-expression of Bcl-2 anti-apoptotic proteins. Studies have shown the use of Allium sativum (garlic) as a herbal supplement among cancer patients. In this study, the…
View article: Accelerated Epigenetic Age Among Women with Invasive Cervical Cancer and HIV-Infection in Nigeria
Accelerated Epigenetic Age Among Women with Invasive Cervical Cancer and HIV-Infection in Nigeria Open
Background Invasive cervical cancer (ICC) is a serious public health burden in Nigeria, where human immunodeficiency virus (HIV) remains highly prevalent. Previous research suggested that epigenetic age acceleration (EAA) could play a role…
View article: Pit Pattern Analysis of Colorectal Polyps Using Storz Professional Image Enhancement System (Spies) Endoscopy
Pit Pattern Analysis of Colorectal Polyps Using Storz Professional Image Enhancement System (Spies) Endoscopy Open
Background: Endoscopic management of colorectal polyps includes detection, characterization, and therapeutic strategies. Pit pattern analysis is a useful tool when differentiating neoplastic and non-neoplastic colorectal polyps. Aim: To co…
View article: Telepathology in Nigeria for Global Health Collaboration
Telepathology in Nigeria for Global Health Collaboration Open
Inadequate pathology personnel and high cost of running a Pathology facility are factors affecting access to timely and quality pathology services in resource-constrained settings. Telepathology is a novel technology that allows Pathologis…
View article: Mismatch Repair Protein Expressions in Cohort of Colorectal Carcinoma Patients in Lagos
Mismatch Repair Protein Expressions in Cohort of Colorectal Carcinoma Patients in Lagos Open
Background: Colorectal carcinoma (CRC) is a major cause of morbidity and mortality worldwide. Microsatellite instability pathway is important in the pathogenesis of CRC. Immunohistochemistry expression of mismatch repair (MMR) proteins ser…
View article: Consensus molecular subtyping of colorectal cancer by immunohistochemistry, an imperative for a resource limited setting
Consensus molecular subtyping of colorectal cancer by immunohistochemistry, an imperative for a resource limited setting Open
Background and Objectives: Studies of colorectal cancer (CRC) molecular heterogeneity have used genome-wide gene expression-based data to group patients into four consensus molecular subtypes (CMS), but the cost and sophistication of analy…
View article: Editorial
Editorial Open
I hereby present to you, the July–December 2021 edition of our esteemed journal, the Nigerian Journal of Gastroenterology and Hepatology, the official publication of the Society for Gastroenterology and Hepatology in Nigeria (SOGHIN). Begi…
View article: A review of breast cancer pathology reports in Nigeria
A review of breast cancer pathology reports in Nigeria Open
The majority of patient records analysed lacked complete documentation of breast cancer histopathological characteristics commonly used in oncology practice. Our study highlights a need to identify and address the contributing factors for …