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View article: Short report: First whole-genome evidence of dengue virus in field-caught mosquitoes from southern Brazil
Short report: First whole-genome evidence of dengue virus in field-caught mosquitoes from southern Brazil Open
Dengue virus (DENV) is a major global health threat whose expansion into temperate regions has been facilitated by climate change and vector adaptation. Despite recurrent epidemics in Brazil, genomic surveillance in mosquitoes remains limi…
View article: Uncovering DENV, CHIKV, and ZIKV in Urban Wastewater in Brazil Through Genomic and Molecular Screening
Uncovering DENV, CHIKV, and ZIKV in Urban Wastewater in Brazil Through Genomic and Molecular Screening Open
This study evaluated and compared molecular methods (Whole Genome Sequencing-WGS, MinION, and RT-qPCR) for the detection of arboviruses Dengue (DENV), Chikungunya (CHIKV), and Zika (ZIKV) in 63 hospital and municipal wastewater samples col…
View article: Uncovering DENV, CHIKV, and ZIKV in Urban Wastewater in Brazil Through Genomic and Molecular Screening
Uncovering DENV, CHIKV, and ZIKV in Urban Wastewater in Brazil Through Genomic and Molecular Screening Open
This study evaluated and compared molecular methods for the detection of arboviruses Dengue (DENV), Chikungunya (CHIKV), and Zika (ZIKV) in wastewaters collected from July 2022 to May 2023 in the region of Belo Horizonte, Brazil. Detection…
View article: Understanding the emergence expansion and impact of oropouche virus
Understanding the emergence expansion and impact of oropouche virus Open
Oropouche virus (OROV) is an emerging zoonotic arbovirus that has recently gained attention due to its rapid geographic expansion and increasing public health significance. Traditionally confined to the Amazon region, OROV has now been det…
View article: Establishing a dengue genomic monitoring in Cuba: uncovering virus dynamics to enhance local response
Establishing a dengue genomic monitoring in Cuba: uncovering virus dynamics to enhance local response Open
This study outlines the development of a dengue genomic monitoring system in the country. The system will contribute to Cuba's public health response, facilitating timely interventions and potentially reducing the disease's impact on the l…
View article: Tratamento cirúrgico e aspectos clínicos da polidactilia em pediatria
Tratamento cirúrgico e aspectos clínicos da polidactilia em pediatria Open
A polidactilia é uma malformação congênita frequente na faixa etária pediátrica, caracterizada pela presença de dedos supranumerários nas mãos ou nos pés. Essa condição pode se manifestar de forma isolada ou como parte de síndromes genétic…
View article: Shifting Dynamics of DENV2 in Costa Rica: Emergence of the Cosmopolitan Genotype (2024)
Shifting Dynamics of DENV2 in Costa Rica: Emergence of the Cosmopolitan Genotype (2024) Open
Dengue remains a major public health challenge. In Costa Rica, we implemented the first nationwide genomic surveillance to track the emergence of the DENV2 Cosmopolitan genotype. Phylogenetic and eco-epidemiological analyses revealed early…
View article: Re-emergence of Yellow Fever Virus in Brazil: Evidence from Forest and peri-urban Settings
Re-emergence of Yellow Fever Virus in Brazil: Evidence from Forest and peri-urban Settings Open
Yellow Fever virus (YFV) continues to challenge public health systems across the Americas, despite decades of successful control and the availability of a highly effective vaccine. Following major outbreaks between 2016 and 2022, YFV re-em…
View article: Anellovirus abundance as an indicator for viral metagenomic classifier utility in plasma samples
Anellovirus abundance as an indicator for viral metagenomic classifier utility in plasma samples Open
Our study underscores the critical impact of classifier selection on diversity indices in metagenomic analyses. Kaiju effectively assigned a wide variety of TTV species, demonstrating it did not require a high volume of reads to capture di…
View article: Spatiotemporal disease suitability prediction for Oropouche virus and the role of vectors across the Americas
Spatiotemporal disease suitability prediction for Oropouche virus and the role of vectors across the Americas Open
Summary Oropouche virus (OROV) is an emerging arbovirus with increasing outbreaks in South America, yet its environmental drivers and potential range remain poorly understood. Using ecological niche modeling (ENM) with random forests, we a…
View article: Travel-associated international spread of Oropouche virus beyond the Amazon
Travel-associated international spread of Oropouche virus beyond the Amazon Open
Oropouche virus (OROV), first detected in Trinidad and Tobago in 1955, was historically confined to the Brazilian Amazon Basin. However, since late 2022, an increasing number of OROV cases have been reported across various regions of Brazi…
View article: Surveillance of Resistance Genes and Phages Reveals Divergent Hospital and Community Wastewater Profiles in the Third Largest Urban Region of Brazil
Surveillance of Resistance Genes and Phages Reveals Divergent Hospital and Community Wastewater Profiles in the Third Largest Urban Region of Brazil Open
View article: Genomics-based timely detection of dengue virus type I genotypes I and V in Uruguay
Genomics-based timely detection of dengue virus type I genotypes I and V in Uruguay Open
This study details a genomics-based approach for the early detection of mosquito-borne pathogens, marked by Uruguay's first ever complete genomic sequencing of Dengue Virus type I genotypes I and V. This pioneering effort has facilitated t…
View article: Dynamics and ecology of a multi-stage expansion of Oropouche virus in Brazil
Dynamics and ecology of a multi-stage expansion of Oropouche virus in Brazil Open
In March 2024, the Pan American Health Organization (PAHO) issued an alert in response to a rapid increase in Oropouche fever cases across South America. Brazil has been particularly affected, reporting a novel reassortant lineage of the O…
View article: Unraveling the Complexity of Chikungunya Virus Infection Immunological and Genetic Insights in Acute and Chronic Patients
Unraveling the Complexity of Chikungunya Virus Infection Immunological and Genetic Insights in Acute and Chronic Patients Open
Background: The chikungunya virus (CHIKV), transmitted by infected Aedes mosquitoes, has caused a significant number of infections worldwide. In Brazil, the emergence of the CHIKV-ECSA genotype in 2014 posed a major public health challenge…
View article: Exploring Dengue Infection in a Vaccinated Individual: Preliminary Molecular Diagnosis and Sequencing Insights
Exploring Dengue Infection in a Vaccinated Individual: Preliminary Molecular Diagnosis and Sequencing Insights Open
This study examines a case involving a 7-year-old child who developed dengue symptoms following Qdenga vaccination. Despite initial negative diagnostic results, molecular analysis confirmed an infection with DENV4. Next-generation sequenci…
View article: Integrated analyses of the transmission history of SARS-CoV-2 and its association with molecular evolution of the virus underlining the pandemic outbreaks in Italy, 2019-2023
Integrated analyses of the transmission history of SARS-CoV-2 and its association with molecular evolution of the virus underlining the pandemic outbreaks in Italy, 2019-2023 Open
The changing patterns of viral spread and variant prevalence throughout Italy's pandemic response underscore the continued importance of flexible public health strategies and genomic surveillance, both of which are crucial for tracking the…
View article: Fatal Oropouche Virus Infections in Nonendemic Region, Brazil, 2024
Fatal Oropouche Virus Infections in Nonendemic Region, Brazil, 2024 Open
We report acute Oropouche virus infections in 2 previously healthy women from a nonendemic region of Brazil outside the Amazon Basin. Infections rapidly progressed to hemorrhagic manifestations and fatal outcomes in 4-5 days. These cases h…
View article: A new lineage nomenclature to aid genomic surveillance of dengue virus
A new lineage nomenclature to aid genomic surveillance of dengue virus Open
Dengue virus (DENV) is currently causing epidemics of unprecedented scope in endemic settings and expanding to new geographical areas. It is therefore critical to track this virus using genomic surveillance. However, the complex patterns o…
View article: Exploring Dengue Infection in a Vaccinated Individual: Preliminary Molecular Diagnosis and Sequencing Insights
Exploring Dengue Infection in a Vaccinated Individual: Preliminary Molecular Diagnosis and Sequencing Insights Open
This study examines a case involving a 7-year-old child who developed dengue symptoms following Qdenga vaccination. Despite initial negative diagnostic results, molecular analysis confirmed an infection with DENV4. Next-generation sequenci…
View article: Rapid Viral Expansion Beyond the Amazon Basin: Increased Epidemic Activity of Oropouche Virus Across the Americas
Rapid Viral Expansion Beyond the Amazon Basin: Increased Epidemic Activity of Oropouche Virus Across the Americas Open
Summary Oropouche virus (OROV), initially detected in Trinidad and Tobago in 1955, has been historically confined to the Amazon Basin. However, since late 2022, OROV has been reported in northern Brazil as well as urban centers in Bolivia,…
View article: Corrigendum: Genomic characterization of SARS-CoV-2 from an indigenous reserve in Mato Grosso do Sul, Brazil
Corrigendum: Genomic characterization of SARS-CoV-2 from an indigenous reserve in Mato Grosso do Sul, Brazil Open
[This corrects the article DOI: 10.3389/fpubh.2023.1195779.].
View article: North–south pathways, emerging variants, and high climate suitability characterize the recent spread of dengue virus serotypes 2 and 3 in the Dominican Republic
North–south pathways, emerging variants, and high climate suitability characterize the recent spread of dengue virus serotypes 2 and 3 in the Dominican Republic Open
View article: Clinical profile of Oropouche Fever in Bahia, Brazil: unexpected fatal cases
Clinical profile of Oropouche Fever in Bahia, Brazil: unexpected fatal cases Open
Oropouche virus (OROV) is an arbovirus transmitted to humans by mosquitoes, with the Culicoides paraensis mosquito species as its primary vector, causing Oropouche fever. Records of an outbreak in Brazil have so far been restricted to Cent…
View article: Insights into SARS-CoV-2 Surveillance among Prison Populations in Mato Grosso do Sul, Brazil, in 2022
Insights into SARS-CoV-2 Surveillance among Prison Populations in Mato Grosso do Sul, Brazil, in 2022 Open
This study examines the epidemiological and genomic characteristics, along with the transmission dynamics, of SARS-CoV-2 within prison units I and II in Campo Grande, Mato Grosso do Sul, Brazil. Conducted between May and October 2022, it r…
View article: Detection of Multiple Human Viruses, including Mpox, Using a Wastewater Surveillance Approach in Brazil
Detection of Multiple Human Viruses, including Mpox, Using a Wastewater Surveillance Approach in Brazil Open
Sewage surveillance can be used as an effective complementary tool for detecting pathogens in local communities, providing insights into emerging threats and aiding in the monitoring of outbreaks. In this study using qPCR and whole genomic…
View article: Exploring Microorganisms Associated to Acute Febrile Illness and Severe Neurological Disorders of Unknown Origin: A Nanopore Metagenomics Approach
Exploring Microorganisms Associated to Acute Febrile Illness and Severe Neurological Disorders of Unknown Origin: A Nanopore Metagenomics Approach Open
Acute febrile illness (AFI) and severe neurological disorders (SNDs) often present diagnostic challenges due to their potential origins from a wide range of infectious agents. Nanopore metagenomics is emerging as a powerful tool for identi…
View article: Correction to “Exploring the urban arbovirus landscape in Rio de Janeiro, Brazil: transmission dynamics and patterns of disease spread” The Lancet Regional Health – Americas 2024;35: 100786
Correction to “Exploring the urban arbovirus landscape in Rio de Janeiro, Brazil: transmission dynamics and patterns of disease spread” The Lancet Regional Health – Americas 2024;35: 100786 Open
View article: Tracing the evolution of the chikungunya virus in Argentina, 2016-2023: independent introductions and prominence of Latin American lineages
Tracing the evolution of the chikungunya virus in Argentina, 2016-2023: independent introductions and prominence of Latin American lineages Open
Chikungunya virus (CHIKV) has emerged as a significant public health concern due to its rapid spread and potential for causing debilitating epidemics. In Argentina, the virus has garnered attention since its introduction to the Americas in…
View article: Exploring the urban arbovirus landscape in Rio de Janeiro, Brazil: transmission dynamics and patterns of disease spread
Exploring the urban arbovirus landscape in Rio de Janeiro, Brazil: transmission dynamics and patterns of disease spread Open