Fatima S Govani
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View article: Correction: Low Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within Minutes
Correction: Low Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within Minutes Open
[This corrects the article DOI: 10.1371/journal.pone.0147990.].
View article: Transcriptome-wide analysis of primary human endothelial cell responses to 1 hour of protein translation inhibition identify nonsense mediated decay targets and a non-coding<i>SLC11A2</i>exon as an acute biomarker
Transcriptome-wide analysis of primary human endothelial cell responses to 1 hour of protein translation inhibition identify nonsense mediated decay targets and a non-coding<i>SLC11A2</i>exon as an acute biomarker Open
Nonsense mediated decay (NMD) lowers the cellular concentration of spliced RNAs harboring premature termination codons (PTC), and inhibition has been proposed as a potential therapeutic method. Conversely, NMD plays regulatory roles throug…
View article: Updates on diagnostic criteria for hereditary haemorrhagic telangiectasia in the light of whole genome sequencing of ‘gene-negative’ individuals recruited to the 100 000 Genomes Project
Updates on diagnostic criteria for hereditary haemorrhagic telangiectasia in the light of whole genome sequencing of ‘gene-negative’ individuals recruited to the 100 000 Genomes Project Open
Hereditary haemorrhagic telangiectasia (HHT) is diagnosed clinically by the Curaçao Criteria of spontaneous recurrent nosebleeds, mucocutaneous telangiectasia at characteristic sites, visceral involvement (arteriovenous malformations [AVMs…
View article: Low Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within Minutes
Low Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within Minutes Open
These data suggest that low dose iron treatments are sufficient to modify the vascular endothelium, and induce a DNA damage response.